Search Results - "Alsharidah, Mansour"
-
1
Biomedical Applications of Quantum Dots: Overview, Challenges, and Clinical Potential
Published in International journal of nanomedicine (01-05-2022)“…Despite the massive advancements in the nanomedicines and their associated research, their translation into clinically-applicable products is still below…”
Get full text
Journal Article -
2
Rosuvastatin-Induced Oral Ulcer: A Case Report and Review of Literature
Published in Case reports in dentistry (29-03-2022)“…Background. The benefits of prescribing statins are well published in the treatment of hypercholesterolemia. With such widespread usage of statins, physicians…”
Get full text
Journal Article -
3
Modification of SWCNTs with hybrid materials ZnO–Ag and ZnO–Au for enhancing bactericidal activity of phagocytic cells against Escherichia coli through NOX2 pathway
Published in Scientific reports (13-10-2022)“…Zinc oxide-silver (ZnO–Ag), and zinc oxide-gold (ZnO–Au) nano-composites were prepared through wet chemical process and laced into single-walled carbon…”
Get full text
Journal Article -
4
Phytochemical Profiling, In Vitro and In Silico Anti-Microbial and Anti-Cancer Activity Evaluations and Staph GyraseB and h -TOP-IIβ Receptor-Docking Studies of Major Constituents of Zygophyllum coccineum L. Aqueous-Ethanolic Extract and Its Subsequent Fractions: An Approach to Validate Traditional Phytomedicinal Knowledge
Published in Molecules (Basel, Switzerland) (22-01-2021)“…, an edible halophytic plant, is part of the traditional medicine chest in the Mediterranean region for symptomatic relief of diabetes, hypertension, wound…”
Get full text
Journal Article -
5
Silver Nanoparticle-Coated Ethyl Cellulose Inhibits Tumor Necrosis Factor-α of Breast Cancer Cells
Published in Drug design, development and therapy (01-01-2021)“…Cancer is one of the leading causes of death worldwide. In many cases, cancer is related to the elevated expression of a significant cytokine known as tumor…”
Get full text
Journal Article -
6
Mesenchymal Stem Cell–Conditioned Media Modulate HUVEC Response to H2O2: Impact on Gene Expression and Potential for Atherosclerosis Intervention
Published in BioMed research international (17-07-2024)“…Through the analysis of the gene expression of critical inflammation-related markers including transforming growth factor-beta 1 (TGF-β1), activating…”
Get full text
Journal Article -
7
Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7
Published in International journal of nanomedicine (01-01-2020)“…The nuclear factor kappa-B (NF-κB) is a major transcription factor responsible for the production of numerous inflammatory mediators, including the tumor…”
Get full text
Journal Article -
8
Targeting the PI3K/pAKT/mTOR/NF‐κB/FOXO3a signaling pathway for suppressing the development of hepatocellular carcinoma in rats: Role of the natural remedic Suaeda vermiculata forssk
Published in Environmental toxicology (01-06-2024)“…Liver malignancy is well recognized as a prominent health concern, with numerous treatment options available. Natural products are considered a renewable…”
Get full text
Journal Article -
9
Octreotide-conjugated silver nanoparticles for active targeting of somatostatin receptors and their application in a nebulized rat model
Published in Nanotechnology reviews (Berlin) (01-01-2022)“…Drug uptake and distribution through cell–receptor interactions are of prime interest in reducing the adverse effects and increasing the therapeutic…”
Get full text
Journal Article -
10
Thymoquinone Lowers Blood Glucose and Reduces Oxidative Stress in a Rat Model of Diabetes
Published in Molecules (Basel, Switzerland) (17-04-2021)“…The aim of the present study was to assess the short-term effects of Thymoquinone (TQ) on oxidative stress, glycaemic control, and renal functions in diabetic…”
Get full text
Journal Article -
11
Formulation of polymeric nanoparticles loaded sorafenib; evaluation of cytotoxicity, molecular evaluation, and gene expression studies in lung and breast cancer cell lines
Published in Nanotechnology reviews (Berlin) (28-02-2022)“…Sorafenib (SFB) is an anticancer drug with sparingly water solubility and reduced bioavailability. Nanoformulation of SFB can increase its dissolution rate and…”
Get full text
Journal Article -
12
Smart Injectable Chitosan Hydrogels Loaded with 5-Fluorouracil for the Treatment of Breast Cancer
Published in Pharmaceutics (17-03-2022)“…The treatment of breast cancer requires long chemotherapy management, which is accompanied by severe side effects. Localized delivery of anticancer drugs helps…”
Get full text
Journal Article -
13
Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs
Published in Biomedicine & pharmacotherapy (01-04-2022)“…Pulmonary fibrosis (PF) is a chronic progressive disease that portends a very poor prognosis. It has been suggested that STAT3 is a potential target in PF…”
Get full text
Journal Article -
14
Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture
Published in Aging cell (01-06-2013)“…Summary The myogenic behaviour of primary human muscle precursor cells (MPCs) obtained from young (aged 20–25 years) and elderly people (aged 67–82 years) was…”
Get full text
Journal Article -
15
Hedgehog signaling is a promising target for the treatment of hepatic fibrogenesis: a new management strategy using itraconazole-loaded nanoparticles
Published in Frontiers in pharmacology (14-05-2024)“…Liver fibrosis is a disease with a great global health and economic burden. Existing data highlights itraconazole (ITRCZ) as a potentially effective…”
Get full text
Journal Article -
16
Comparative Phytochemical Profile and Biological Activity of Four Major Medicinal Halophytes from Qassim Flora
Published in Plants (Basel) (18-10-2021)“…Four halophytic plants, Lycium shawii, Anabasis articulata, Rumex vesicarius, and Zilla spinosa, growing in the central Qassim area, Saudi Arabia, were…”
Get full text
Journal Article -
17
Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer
Published in Bioinorganic chemistry and applications (2022)“…Tumor necrosis factor (TNF-α) and inflammatory cytokine (IL-6) play a vital role in various cellular incidents such as the proliferation and death of cells…”
Get full text
Journal Article -
18
Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients
Published in Saudi pharmaceutical journal (01-01-2018)“…Type 2 diabetes is a chronic condition that requires pharmacotherapy interventions. Metformin and gliclazide are widely used drugs in monotherapy. However,…”
Get full text
Journal Article -
19
Retardation of Bacterial Biofilm Formation by Coating Urinary Catheters with Metal Nanoparticle-Stabilized Polymers
Published in Microorganisms (Basel) (27-06-2022)“…Urinary catheter infections remain an issue for many patients and can complicate their health status, especially for individuals who require long-term…”
Get full text
Journal Article -
20
Antimicrobial, Antibiofilm, and Antioxidant Potentials of Four Halophytic Plants, Euphorbia chamaesyce , Bassia arabica , Fagonia mollis , and Haloxylon salicornicum , Growing in Qassim Region of Saudi Arabia: Phytochemical Profile and In Vitro and In Silico Bioactivity Investigations
Published in Antibiotics (Basel) (02-03-2023)“…The current study aimed to investigate the phytochemical contents and antioxidant, antimicrobial, and antibiofilm activities of four halophytic plants, namely,…”
Get full text
Journal Article