Search Results - "Alshareeda, Alaa"

Scaffold-Free 3-D Cell Sheet Technique Bridges the Gap between 2-D Cell Culture and Animal Models by Alghuwainem, Ayidah, Alshareeda, Alaa T, Alsowayan, Batla

“…Various tissue engineering techniques have been created in research spanning two centuries, resulting in new opportunities for growing cells in culture and the…”
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Differential expression and regulation of ADAD1, DMRTC2, PRSS54, SYCE1, SYCP1, TEX101, TEX48, and TMPRSS12 gene profiles in colon cancer tissues and their in vitro response to epigenetic drugs by Almutairi, Mikhlid H, Alrubie, Turki M, Alshareeda, Alaa T, Albarakati, Nada, Almotiri, Alhomidi, Alamri, Abdullah M, Almutairi, Bader O, Alanazi, Mohammad

“…Colon cancer (CC) is a significant cause of death worldwide, particularly in Saudi Arabia. To increase the accuracy of diagnosis and treatment, it is important…”
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Preparing the Bone Tissue Regeneration Ground by Exosomes: From Diagnosis to Therapy by Al-Sowayan, Batla, Alammari, Farah, Alshareeda, Alaa

“…Bone tissue engineering employs acellular scaffolds or scaffolds, along with cells and growth factors, to provide the mechanical support needed, as well as…”
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Homologous recombination mRNAs (RAD21, RAD50 and BARD1) have a potentially poor prognostic role in ERBB2-low bladder cancer patients by Albarakati, Nada, Al-Ghamdi, Hanin, Al-Sowayan, Batla, Alshareeda, Alaa

“…Human epidermal growth factor receptor 2 (HER2/ ERBB2 ) factor is known to be implicated in many malignancies and the potential of it as a prognostic biomarker…”
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The effect of human placental chorionic villi derived mesenchymal stem cell on triple-negative breast cancer hallmarks by Alshareeda, Alaa T, Rakha, Emad, Alghwainem, Ayidah, Alrfaei, Bahauddeen, Alsowayan, Batla, Albugami, Abdullah, Alsubayyil, Abdullah M, Abomraee, Mohmed, Mohd Zin, Nur Khatijah

“…Mesenchymal stem cells (MSCs) can influence the tumour microenvironment (TEM) and play a major role in tumourigenesis. Triple-negative [Ostrogen receptor…”
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The potential of cell sheet technique on the development of hepatocellular carcinoma in rat models by Alshareeda, Alaa T, Sakaguchi, Katsuhisa, Abumaree, Mohammed, Mohd Zin, Nur Khatijah, Shimizu, Tatsuya

“…Hepatocellular carcinoma (HCC) is considered the 3rd leading cause of death by cancer worldwide with the majority of patients were diagnosed in the late…”
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Hidden regulators: the emerging roles of lncRNAs in brain development and disease by Alammari, Farah, Al-Hujaily, Ensaf M, Alshareeda, Alaa, Albarakati, Nada, Al-Sowayan, Batla S

“…Long non-coding RNAs (lncRNAs) have emerged as critical players in brain development and disease. These non-coding transcripts, which once considered as…”
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Nanotechnology: A revolutionary approach to prevent breast cancer recurrence by Alshareeda, Alaa T., Nur Khatijah, M.Z., Al-Sowayan, Batla S.

“…Breast cancer is the most prevalent malignancy in women worldwide and one of the deadliest after lung cancer. Currently, standard treatment approaches for…”
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Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer by Arora, Arvind, Abdel-Fatah, Tarek M A, Agarwal, Devika, Doherty, Rachel, Moseley, Paul M, Aleskandarany, Mohammed A, Green, Andrew R, Ball, Graham, Alshareeda, Alaa T, Rakha, Emad A, Chan, Stephen Y T, Ellis, Ian O, Madhusudan, Srinivasan

“…Bloom syndrome helicase (BLM) has key roles in homologous recombination repair, telomere maintenance, and DNA replication. Germ-line mutations in the BLM gene…”
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Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer by Alshareeda, Alaa T., Negm, Ola H., Albarakati, Nada, Green, Andrew R., Nolan, Christopher, Sultana, Rebeka, Madhusudan, Srinivasan, benHasouna, Ahmed, Tighe, Paddy, Ellis, Ian O., Rakha, Emad A.

“…Although the role of BRCA1 and the homologous recombination (HR) pathway in breast cancer (BC) has been extensively studied, the alternative repair pathway for…”
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Cancer of Unknown Primary Site: Real Entity or Misdiagnosed Disease? by Alshareeda, Alaa T, Al-Sowayan, Batla S, Alkharji, Reem R, Aldosari, Sahar M, Al Subayyil, Abdullah M, Alghuwainem, Ayidah

“…Metastasis is a late event in the progression of any tumour. However, invasive cancers are occasionally detected in the form of metastatic lesions without a…”
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Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo by Alshareeda, Alaa T, Alsowayan, Batla, Almubarak, Abdullah, Alghuwainem, Ayidah, Alshawakir, Yasser, Alahmed, Mohammed

“…An in vivo animal model that mimics human cancer could have various applications that deliver significant clinical information. The currently used techniques…”
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FTHL17, PRM2, CABYR, CPXCR1, ADAM29, and CABS1 are highly expressed in colon cancer patients and are regulated in vitro by epigenetic alterations by Alrubie, Turki M., Shaik, Jilani P., Alamri, Abdullah M., Alanazi, Mohammad, Alshareeda, Alaa T., alqarni, Ayyob, Alawfi, Homoud G., Almaiman, Sarah M., Almutairi, Mikhlid H.

“…Colon cancer is a serious public health issue and a major cause of cancer-related mortality worldwide, including Saudi Arabia. Knowledge of genes associated…”
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SUMOylation proteins in breast cancer by Alshareeda, Alaa T., Negm, Ola H., Green, Andrew R., Nolan, Christopher, Tighe, Paddy, Albarakati, Nada, Sultana, Rebeka, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.

“…Small Ubiquitin-like Modifier proteins (or SUMO) modify the function of protein substrates involved in various cellular processes including DNA damage response…”
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Characteristics of basal cytokeratin expression in breast cancer by Alshareeda, Alaa T., Soria, Daniele, Garibaldi, Jonathan M., Rakha, Emad, Nolan, Christopher, Ellis, Ian O., Green, Andrew R.

“…Breast cancer is recognised to be a heterogeneous disease and the second most common cause of morbidity and mortality worldwide in women. Basal-like breast…”
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Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer by Alshareeda, Alaa T., Rakha, Emad A., Nolan, Christopher C., Ellis, Ian O., Green, Andrew R.

“…FABP7 is a member of the multi-gene fatty acid binding protein family. It is expressed in the mammary gland and has been shown to function as inhibitor of…”
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Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein by Alshareeda, Alaa Tarig, Negm, Ola H., Aleskandarany, Mohammed A., Green, Andrew R., Nolan, Christopher, TigHhe, Patrick J., Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.

“…Impaired DNA damage response (DDR) may play a fundamental role in the pathogenesis of breast cancer (BC). RAD51 is a key player in DNA double-strand break…”
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Biological and clinical significance of PARP1 protein expression in breast cancer by Green, Andrew R., Caracappa, Daniela, Benhasouna, Ahmed A., Alshareeda, Alaa, Nolan, Christopher C., Macmillan, R. Douglas, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.

“…Poly(ADP-ribose) polymerase-1 (PARP1) is a key facilitator of DNA repair. PARP inhibitors have gained recent attention as promising therapeutic agents for the…”
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Exploring the Potential of Mesenchymal Stem Cell Sheet on The Development of Hepatocellular Carcinoma In Vivo by Alshareeda, Alaa T, Alsowayan, Batla, Almubarak, Abdullah, Alghuwainem, Ayidah, Alshawakir, Yasser, Alahmed, Mohammed

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Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer by Jerjees, Dena A., Alabdullah, M., Green, Andrew R., Alshareeda, Alaa, Macmillan, R. D., Ellis, Ian O., Rakha, Emad A.

“…The definition of Luminal-B subclass of breast cancer (BC) varies in literature. In this study, we have compared the proliferation status; assessed using KI67…”
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