Search Results - "Alshamrani, Ali"

Enhancing pyramid solar still performance using suspended v-steps, reflectors, Peltier cooling, forced condensation, and thermal storing materials by Alshamrani, Ali

“…This work aims at enhancing the thermal efficiency of pyramid distiller solar still (PDSS). A modified version (MPDSS) was developed, featuring suspended…”
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Roles of microRNAs in Ovarian Cancer Tumorigenesis: Two Decades Later, What Have We Learned? by Alshamrani, Ali A.

“…Ovarian cancer is one of the top gynecological malignancies that cause deaths among females in the United States. At the molecular level, significant progress…”
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Membrane Depolarization Inhibits BIMEL Upregulation but Prevents Neuronal Apoptosis Primarily by Increasing Cellular GSH Levels by Alshamrani, Ali A., Franklin, James L.

“…Sympathetic neurons deprived of nerve growth factor (NGF) die by apoptosis. Chronic depolarization with elevated concentrations of extracellular potassium ([K…”
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Potential Antioxidant Activity of Apigenin in the Obviating Stress-Mediated Depressive Symptoms of Experimental Mice by Alghamdi, Adel, Almuqbil, Mansour, Alrofaidi, Mohammad A, Burzangi, Abdulhadi S, Alshamrani, Ali A, Alzahrani, Abdullah R, Kamal, Mehnaz, Imran, Mohd, Alshehri, Sultan, Mannasaheb, Basheerahmed Abdulaziz, Alomar, Nasser Fawzan, Asdaq, Syed Mohammed Basheeruddin

“…This study aimed to examine the antidepressant properties of apigenin in an experimental mouse model of chronic mild stress (CMS). Three weeks following CMS,…”
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Coronavirus disease 2019 pandemic stress and its effects on irritable bowel syndrome patients in Saudi Arabia by Alzahrani, Mohammed A., Alshamrani, Ali S., Ahmasani, Ibrahim M., Alahmari, Fahad S., Asiri, Ali H., Alshehri, Abdullah M., Alsamghan, Awad S., Awadalla, Nabil J.

“…Coronavirus disease 2019 (COVID-19 pandemic has affected the psychological health of people, causing a higher level of stress. Stress can exaggerate the…”
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Plumbagin Alleviates Intracerebroventricular-Quinolinic Acid Induced Depression-like Behavior and Memory Deficits in Wistar Rats by Kumar Arora, Mandeep, Ratra, Anish, Asdaq, Syed Mohammed Basheeruddin, Alshamrani, Ali A, Alsalman, Abdulkhaliq J, Kamal, Mehnaz, Tomar, Ritu, Sahoo, Jagannath, Ashok, Jangra, Imran, Mohd

“…Plumbagin, a hydroxy-1,4-naphthoquinone, confers neuroprotection via antioxidant and anti-inflammatory properties. The present study aimed to assess the effect…”
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MAP kinase inhibitor PD98059 regulates Th1, Th9, Th17, and natural T regulatory cells in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis by Ahmad, Sheikh F., Ansari, Mushtaq A., Nadeem, Ahmed, Bakheet, Saleh A., Alasmari, Abdullah F., Shahid, Mudassar, Al-Mazroua, Haneen A., Alomar, Hatun A., AsSobeai, Homood M., Alshamrani, Ali A., Attia, Sabry M.

“…Experimental autoimmune encephalitis (EAE), an animal model of multiple sclerosis (MS), provides significant insights into the mechanisms that initiate and…”
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Comprehensive evaluation of six interventions for hospitalized patients with COVID-19: A propensity score matching study by Alshamrani, Ali A., Assiri, Ahmed M., Almohammed, Omar A.

“…The purpose of this study was to evaluate the effectiveness of either hydroxychloroquine, triple combination therapy (TCT), favipiravir, dexamethasone,…”
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miR-122-5p Expression and Secretion in Melanoma Cells Is Amplified by the LPAR3 SH3-Binding Domain to Regulate Wnt1 by Byrnes, Charnel C, Jia, Wei, Alshamrani, Ali A, Kuppa, Sudeepti S, Murph, Mandi M

“…The lysophosphatidic acid receptor-3 (LPAR3) is a G protein-coupled receptor that mediates viability among malignant cells and aggressiveness among certain…”
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Dulaglutide rescues the elevated testicular dysfunction in a mouse model of high-fat diet-induced obesity by Attia, Sabry M., Alshamrani, Ali A., Ahmad, Sheikh F., Albekairi, Norah A., Nadeem, Ahmed, Attia, Mohamed S.M., Ansari, Mushtaq A., Alqahtani, Faleh, Bakheet, Saleh A., Harisa, Gamaleldin I.

“…Obesity is a well-known risk factor for testicular function; however, dulaglutide's effect on the testis in obesity has received little attention. Currently,…”
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Dapagliflozin suppresses diabetes-induced oxidative DNA damage and hypermethylation in mouse somatic cells by Attia, Sabry M., Albekairi, Norah A., Alshamrani, Ali A., Ahmad, Sheikh F., Almutairi, Faris, Attia, Mohamed S.M., Ansari, Mushtaq A., Bakheet, Saleh A., Harisa, Gamaleldin I., Nadeem, Ahmed

“…Diabetes mellitus is a complex metabolic disorder resulting from the interplay of environmental, genetic, and epigenetic factors that increase the risk of…”
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CXCR3 antagonist NBI-74330 mitigates joint inflammation in Collagen-Induced arthritis model in DBA/1J mice by Ahmad, Sheikh F., Nadeem, Ahmed, Ansari, Mushtaq A., Bakheet, Saleh A., Alomar, Hatun A., Al-Mazroua, Haneen A., Ibrahim, Khalid E., Alshamrani, Ali A., Al-Hamamah, Mohammed A., Alfardan, Ali S., Attia, Sabry M.

“…•We investigated the possible anti-arthritic effects of the NBI-74330.•We investigated the effect of NBI-74330 on the inflammatory mediators of RA.•NBI-74330…”
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A Rare Abdominal Pain Associated With Chronic Intestinal Schistosomiasis Diagnosed Endoscopically: A Case Study From Saudi Arabia by Nasser Alsharif, Saeed, Saleh Alshamrani, Ali, Hadi Asiri, Dawlah, Yahya Al-Mani, Salihah

“…Chronic intestinal schistosomiasis (CIS) refers to the long-term effects of infection with Schistosoma parasites in the intestines. This condition typically…”
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Saxagliptin, a selective dipeptidyl peptidase-4 inhibitor, alleviates somatic cell aneugenicity and clastogenicity in diabetic mice by Attia, Sabry M., Ahmad, Sheikh F., Nadeem, Ahmed, Attia, Mohamed S.M., Ansari, Mushtaq A., Ashour, Abdelkader E., Albekairi, Norah A., Al-Hamamah, Mohammed A., Alshamrani, Ali A., Bakheet, Saleh A.

“…Diabetes-related complications are becoming increasingly common as the global prevalence of diabetes increases. Diabetes is also linked to a high risk of…”
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Development and Evaluation of a Physiologically Based Pharmacokinetic Model of Labetalol in Healthy and Diseased Populations by Hafsa, Hafsa, Zamir, Ammara, Rasool, Muhammad Fawad, Imran, Imran, Saeed, Hamid, Ahmad, Tanveer, Alsanea, Sary, Alshamrani, Ali A, Alruwaili, Abdullah H, Alqahtani, Faleh

“…Labetalol is a drug that exhibits both alpha and beta-adrenergic receptor-blocking properties. The American Heart Association/American Stroke Association…”
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miRNA-driven sensitization of breast cancer cells to Doxorubicin treatment following exposure to low dose of Zinc Oxide nanoparticles by Alshamrani, Ali A., Bin Salman, Sami B., Alsaleh, Nasser B., Assiri, Mohammed A., Almutairi, Mohammed M., Almudimeegh, Sultan, Alwhaibi, Abdulrahman, As Sobeai, Homood M.

“…The impact of Engineered nanomaterials (ENMs) (i.e., Zinc Oxide nanoparticles (ZnO NPs)) on human health has been investigated at high and unrealistic exposure…”
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Effect of Apremilast on LPS-induced immunomodulation and inflammation via activation of Nrf2/HO-1 pathways in rat lungs by Al-Harbi, Naif O., Imam, Faisal, Al-Harbi, Mohammad Matar, Qamar, Wajhul, Aljerian, Khaldoon, Khalid Anwer, Md, Alharbi, Mohammed, Almudimeegh, Sultan, Alhamed, Abdullah S., Alshamrani, Ali A

“…•Lipopolysaccharides induces inflammation and immunomodulation.•Lipopolysaccharides decreases CD161+ T cells population while decreases CD31b/c+ Cells…”
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Bruton’s tyrosine kinase inhibition suppresses neutrophilic inflammation and restores histone deacetylase 2 expression in myeloid and structural cells in a mixed granulocytic mouse model of asthma by Nadeem, Ahmed, Alshehri, Samiyah, Al-Harbi, Naif O., Ahmad, Sheikh F., Albekairi, Norah A., Alqarni, Saleh A., Ibrahim, Khaild E., Alfardan, Ali S., Alshamrani, Ali A., Bin Salman, Sami B., Attia, Sabry M.

“…•CD11c+ cells, neutrophils and AECs, and lung have decreased HDAC2 and increased p-NFkB levels in mice with mixed granulocytic asthma.•CD11c+ cells,…”
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Tricho-hepato-enteric syndrome: Retrospective multicenter experience in Saudi Arabia by Alsaleem, Badr, Hasosah, Mohammed, Ahmed, Amna, Al Hatlani, Maher, Alanazi, Aziz, Al-Hussaini, Abdulrahman, Asery, Ali, Alghamdi, Khalid, AlRuwaithi, Muhanad, Khormi, Musa, Al Sarkhy, Ahmed, Alshamrani, Ali

“…Background: Trichohepatoenteric syndrome (THES) is a very rare disorder that is characterized by intractable congenital diarrhea, woolly hair, intrauterine…”
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Dulaglutide reduces oxidative DNA damage and hypermethylation in the somatic cells of mice fed a high‐energy diet by restoring redox balance, inflammatory responses, and DNA repair gene expressions by Attia, Sabry M., Alshamrani, Ali A., Ahmad, Sheikh F., Albekairi, Norah A., Nadeem, Ahmed, Attia, Mohamed S. M., Ansari, Mushtaq A., Almutairi, Faris, Bakheet, Saleh A.

“…Obesity is an established risk factor for numerous malignancies, although it remains uncertain whether the disease itself or weight‐loss drugs are responsible…”
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