Search Results - "Alshahrani, Mohammad Y."
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Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications
Published in BioMed research international (2022)“…Plants generally secrete secondary metabolites in response to stress. These secondary metabolites are very useful for humankind as they possess a wide range of…”
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Implementation of a Blockchain System Using Improved Elliptic Curve Cryptography Algorithm for the Performance Assessment of the Students in the E-Learning Platform
Published in Applied sciences (01-01-2022)“…Blockchain technology allows for the decentralized creation of a propagated record of digital events, in which third parties do not control information and…”
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Role of Nanotechnology in Overcoming the Multidrug Resistance in Cancer Therapy: A Review
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Cancer is one of the leading causes of morbidity and mortality around the globe and is likely to become the major cause of global death in the coming years. As…”
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Impacts of sugarcane industrial effluent as an alternate source of irrigation on growth, chlorophyll contents and antioxidants of different canola varieties
Published in Scientific reports (22-01-2024)“…The sugarcane industry often utilizes effluent for irrigation purposes; however, its intricate composition and elevated metal contaminants pose a potential…”
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A dynamical study of SARS-COV-2: A study of third wave
Published in Results in physics (01-10-2021)“…The coronavirus still an epidemic in most countries of the world and put the people in danger with so many infected cases and death. Considering the third wave…”
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Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate
Published in BMC microbiology (14-05-2024)“…Multidrug-resistant (MDR) P. aeruginosa is a rising public health concern, challenging the treatment of such a ubiquitous pathogen with monotherapeutic…”
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Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis
Published in Scientific reports (31-07-2024)“…The Middle East has witnessed a greater spread of infectious Dengue viruses, with serotype 2 (DENV-2) being the most prevalent form. Through this work,…”
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Effects of ginger extract and/or propolis extract on immune system parameters of vaccinated broilers
Published in Poultry science (01-10-2023)“…Newcastle disease (ND), avian influenza (AI, H5N8), and infectious bronchitis (IB) are important diseases in the poultry industry and cause significant losses…”
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Computational Screening of Natural Compounds for Identification of Potential Anti-Cancer Agents Targeting MCM7 Protein
Published in Molecules (Basel, Switzerland) (28-09-2021)“…Minichromosome maintenance complex component 7 (MCM7) is involved in replicative licensing and the synthesis of DNA, and its overexpression is a fascinating…”
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High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma
Published in Journal of computer-aided molecular design (01-12-2021)“…Paradoxical Raf activation via Raf dimerization is a major drawback of wild/mutant B-Raf inhibitors. Herein, we report that CB-1 a novel, potent B-Raf/c-Raf…”
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Quercetin-Ameliorated, Multi-Walled Carbon Nanotubes-Induced Immunotoxic, Inflammatory, and Oxidative Effects in Mice
Published in Molecules (Basel, Switzerland) (25-03-2022)“…The expanding uses of carbon nanotubes (CNTs) in industry and medicine have raised concerns about their toxicity on human and animal health. CNTs, including…”
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Antimicrobial peptide moricin induces ROS mediated caspase-dependent apoptosis in human triple-negative breast cancer via suppression of notch pathway
Published in Cancer cell international (21-06-2023)“…Breast cancer is the world's most prevalent cancer among women. Microorganisms have been the richest source of antibiotics as well as anticancer drugs. Moricin…”
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Combinatorial biosynthesis of novel aminoglycoside antibiotics via pathway engineering
Published in AMB Express (16-09-2024)“…With the current spread of clinically relevant multidrug-resistant (MDR) pathogens, insufficient unearthing of new anti-infectives, and the high cost required…”
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Quercetin alleviated multi-walled carbon nanotubes-induced neurotoxicity in mice through inhibition of oxidation, inflammation, and pyroptosis
Published in Biomedicine & pharmacotherapy (01-07-2022)“…Recently, we reported that quercetin (Que) could alleviate immunotoxicity induced by pristine multi-walled carbon nanotubes (MWCNTs) in mice. In the present…”
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Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System
Published in Gels (28-01-2022)“…Drug instillation via a topical route is preferred since it is desirable and convenient due to the noninvasive and easy drug access to different segments of…”
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Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments
Published in Current issues in molecular biology (27-10-2021)“…The use of pharmaceuticals to treat Major Depressive Disorder (MDD) has several drawbacks, including severe side effects. Natural compounds with great efficacy…”
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Identification of New Mycobacterium tuberculosis Proteasome Inhibitors Using a Knowledge-Based Computational Screening Approach
Published in Molecules (Basel, Switzerland) (16-04-2021)“…(Mtb) is a deadly tuberculosis (TB)-causing pathogen. The proteasome is vital to the survival of Mtb and is therefore validated as a potential target for…”
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Metformin Suppresses Thioacetamide-Induced Chronic Kidney Disease in Association with the Upregulation of AMPK and Downregulation of Oxidative Stress and Inflammation as Well as Dyslipidemia and Hypertension
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Toxic chemicals such as carbon tetrachloride and thioacetamide (TAA) are reported to induce hepato-nephrotoxicity. The potential protective outcome of the…”
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The influence of dietary supplementation with fermented agro-industrial residue of faba bean on Japanese quail performance, immunity, gut microbiota, blood chemistry, and antioxidant status
Published in Poultry science (01-09-2024)“…Antibiotic overuse in poultry feeds has disastrous implications; consequently, long-term alternatives must be developed. As a result, the current study aims to…”
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