Search Results - "Alshahrani, Mohammad"
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Current trends and future perspectives of nanomedicine for the management of colon cancer
Published in European journal of pharmacology (05-11-2021)“…Colon cancer (CC) kills countless people every year throughout the globe. It persists as one of the highly lethal diseases to be treated because the overall…”
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Flavonoids a Bioactive Compound from Medicinal Plants and Its Therapeutic Applications
Published in BioMed research international (2022)“…Plants generally secrete secondary metabolites in response to stress. These secondary metabolites are very useful for humankind as they possess a wide range of…”
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Waste biomass based potential bioadsorbent for lead removal from simulated wastewater
Published in Bioresource technology (01-04-2022)“…[Display omitted] •Bioadsorbent prepared with seed kernel with cover of mango (M) and jamun (JP)•The maximum lead adsorption capacities ̃39.15 mg/g for M and…”
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Implementation of a Blockchain System Using Improved Elliptic Curve Cryptography Algorithm for the Performance Assessment of the Students in the E-Learning Platform
Published in Applied sciences (01-01-2022)“…Blockchain technology allows for the decentralized creation of a propagated record of digital events, in which third parties do not control information and…”
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Role of Nanotechnology in Overcoming the Multidrug Resistance in Cancer Therapy: A Review
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Cancer is one of the leading causes of morbidity and mortality around the globe and is likely to become the major cause of global death in the coming years. As…”
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Prevalence of obesity and overweight among type 2 diabetic patients in Bisha, Saudi Arabia
Published in Journal of family medicine and primary care (01-01-2021)“…Context: Obesity is a significant worldwide public health issue and one of the significant risk factors for type 2 diabetes and cardiovascular diseases. Aims:…”
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A detailed insight of the tumor targeting using nanocarrier drug delivery system
Published in Drug delivery (01-12-2023)“…Human struggle against the deadly disease conditions is continued since ages. The contribution of science and technology in fighting against these diseases…”
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Insilco and Invitro approaches identify novel dual PI3K/AKT pathway inhibitors to control acute myeloid leukemia cell proliferations
Published in Medical oncology (Northwood, London, England) (08-10-2022)“…Acute myeloid leukemia (AML) is characterized by disruption of intracellular signaling due to aberration of extracellular signaling pathways, namely PI3K/AKT…”
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Machine learning investigation of tuberculosis with medicine immunity impact
Published in Diagnostic microbiology and infectious disease (01-11-2024)“…Tuberculosis (T.B.) remains a prominent global cause of health challenges and death, exacerbated by drug-resistant strains such as multidrug-resistant…”
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Investigation of dual inhibition of antibacterial and antiarthritic drug candidates using combined approach including molecular dynamics, docking and quantum chemical methods
Published in Computational biology and chemistry (01-12-2024)“…Emerging antibiotic resistance in bacteria threatens immune efficacy and increases susceptibility to bone degradation and arthritic disorders. In our current…”
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Coconut waste valorization to produce biochar catalyst and its application in cellulose-degrading enzymes production via SSF
Published in International journal of biological macromolecules (15-06-2023)“…Solid waste management and waste valorization are key concerns and challenges around the globe. Solid wastes generated by food industries are found in a…”
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Mitigating effect of pomegranate peel extract against the furan induced testicular injury by apoptosis, steroidogenic enzymes and oxidative stress
Published in Chemosphere (Oxford) (01-06-2024)“…Furan is generated in a wide array of heat-treated foods through thermal degradation, leading to severe impairments in the male reproductive system. The main…”
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Identification of ZINC08101049 as a potential IL1β inhibitor through molecular docking and MD simulations for cancer therapeutics
Published in Journal of biomolecular structure & dynamics (19-01-2024)“…Cancer is a significant global health concern that has a major impact on morbidity and mortality worldwide. Research has demonstrated the involvement of…”
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Impacts of sugarcane industrial effluent as an alternate source of irrigation on growth, chlorophyll contents and antioxidants of different canola varieties
Published in Scientific reports (22-01-2024)“…The sugarcane industry often utilizes effluent for irrigation purposes; however, its intricate composition and elevated metal contaminants pose a potential…”
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A dynamical study of SARS-COV-2: A study of third wave
Published in Results in physics (01-10-2021)“…The coronavirus still an epidemic in most countries of the world and put the people in danger with so many infected cases and death. Considering the third wave…”
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Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate
Published in BMC microbiology (14-05-2024)“…Multidrug-resistant (MDR) P. aeruginosa is a rising public health concern, challenging the treatment of such a ubiquitous pathogen with monotherapeutic…”
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High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma
Published in Journal of computer-aided molecular design (01-12-2021)“…Paradoxical Raf activation via Raf dimerization is a major drawback of wild/mutant B-Raf inhibitors. Herein, we report that CB-1 a novel, potent B-Raf/c-Raf…”
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Multi-epitope peptide vaccines targeting dengue virus serotype 2 created via immunoinformatic analysis
Published in Scientific reports (31-07-2024)“…The Middle East has witnessed a greater spread of infectious Dengue viruses, with serotype 2 (DENV-2) being the most prevalent form. Through this work,…”
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High-throughput screening and in vitro evaluation of CSB-0914; a novel small molecule NF-κB inhibitor attenuating inflammatory responses through NF-κB, Nrf2 and HO-1 cross-talk
Published in Journal of biomolecular structure & dynamics (21-12-2023)“…Unpleasant side effects of standard inflammatory drugs urges search for novel therapeutic candidates. This study aims in identifying novel anti-inflammatory…”
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Effects of ginger extract and/or propolis extract on immune system parameters of vaccinated broilers
Published in Poultry science (01-10-2023)“…Newcastle disease (ND), avian influenza (AI, H5N8), and infectious bronchitis (IB) are important diseases in the poultry industry and cause significant losses…”
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