Search Results - "Alshaer, Walhan"

Liposomes: structure, composition, types, and clinical applications by Nsairat, Hamdi, Khater, Dima, Sayed, Usama, Odeh, Fadwa, Al Bawab, Abeer, Alshaer, Walhan

“…Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high…”
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siRNA: Mechanism of action, challenges, and therapeutic approaches by Alshaer, Walhan, Zureigat, Hadil, Al Karaki, Arwa, Al-Kadash, Abdulfattah, Gharaibeh, Lobna, Hatmal, Ma'mon M., Aljabali, Alaa A.A., Awidi, Abdalla

“…Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to become an essential approach in treating a variety of infectious,…”
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Aptamers Chemistry: Chemical Modifications and Conjugation Strategies by Odeh, Fadwa, Nsairat, Hamdi, Alshaer, Walhan, Ismail, Mohammad A, Esawi, Ezaldeen, Qaqish, Baraa, Bawab, Abeer Al, Ismail, Said I

“…Soon after they were first described in 1990, aptamers were largely recognized as a new class of biological ligands that can rival antibodies in various…”
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Synergistic combination of doxorubicin with hydralazine, and disulfiram against MCF-7 breast cancer cell line by Lafi, Zainab, Alshaer, Walhan, Gharaibeh, Lobna, Alqudah, Dana A, AlQuaissi, Baidaa, Bashaireh, Banan, Ibrahim, Abed Alqader

“…Disulfiram and hydralazine have recently been reported to have anti-cancer action, and repositioned to be used as adjuvant in cancer therapy. Chemotherapy…”
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Quality by Design Approach in Liposomal Formulations: Robust Product Development by Alshaer, Walhan, Nsairat, Hamdi, Lafi, Zainab, Hourani, Omar M, Al-Kadash, Abdulfattah, Esawi, Ezaldeen, Alkilany, Alaaldin M

“…Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal formulations are a major platform in nanomedicine, with more than…”
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Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2 by Hatmal, Ma'mon M, Alshaer, Walhan, Al-Hatamleh, Mohammad A I, Hatmal, Malik, Smadi, Othman, Taha, Mutasem O, Oweida, Ayman J, Boer, Jennifer C, Mohamud, Rohimah, Plebanski, Magdalena

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has recently emerged in China and caused a disease called coronavirus disease 2019 (COVID-19)…”
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Noncovalent functionalization of carbon nanotubes as a scaffold for tissue engineering by Assali, Mohyeddin, Kittana, Naim, Alhaj-Qasem, Sahar, Hajjyahya, Muna, Abu-Rass, Hanood, Alshaer, Walhan, Al-Buqain, Rula

“…Tissue engineering is one of the hot topics in recent research that needs special requirements. It depends on the development of scaffolds that allow tissue…”
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Preparation, Characterization, and Anticancer Effects of Capsaicin-Loaded Nanoliposomes by Al-Samydai, Ali, Alshaer, Walhan, Al-Dujaili, Emad A S, Azzam, Hanan, Aburjai, Talal

“…Medicinal plants have proven their value as a source of molecules with therapeutic potential, and recent studies have shown that capsaicin has profound…”
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Aptamer-Aptamer Chimera for Targeted Delivery and ATP-Responsive Release of Doxorubicin into Cancer Cells by Esawi, Ezaldeen, Alshaer, Walhan, Mahmoud, Ismail Sami, Alqudah, Dana A, Azab, Bilal, Awidi, Abdalla

“…Aptamers offer a great opportunity to develop innovative drug delivery systems that can deliver cargos specifically into targeted cells. In this study, a…”
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Synthesis, Characterization, and Assessment of Anti-Cancer Potential of ZnO Nanoparticles in an In Vitro Model of Breast Cancer by Aljabali, Alaa A A, Obeid, Mohammad A, Bakshi, Hamid A, Alshaer, Walhan, Ennab, Raed M, Al-Trad, Bahaa, Al Khateeb, Wesam, Al-Batayneh, Khalid M, Al-Kadash, Abdulfattah, Alsotari, Shrouq, Nsairat, Hamdi, Tambuwala, Murtaza M

“…Advanced innovations for combating variants of aggressive breast cancer and overcoming drug resistance are desired. In cancer treatment, ZnO nanoparticles…”
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Selection and targeting of EpCAM protein by ssDNA aptamer by Alshaer, Walhan, Ababneh, Nida, Hatmal, Mamon, Izmirli, Heba, Choukeife, Moujab, Shraim, Alaa, Sharar, Nour, Abu-Shiekah, Aya, Odeh, Fadwa, Al Bawab, Abeer, Awidi, Abdalla, Ismail, Said

“…Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and…”
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Editorial: Anti-cancer drug delivery: lipid-based nanoparticles by Alkilany, Alaaldin M, Elhissi, Abdelbary, Alshaer, Walhan, Kunwar, Amit, Giri, Jyotsnendu

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Cinnamaldehyde-cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity by Al Tbakhi, Bayan, Nsairat, Hamdi, Alshaer, Walhan, Al-Kadash, Abdulfattah, Helal, Wissam, Alrawashdeh, Lubna, Day, Anthony, Assaf, Khaleel I, Hassouneh, Rola, Odeh, Fadwa, Al Bawab, Abeer

“…This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes (CB[7]-Cinn) and their…”
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Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review by Khater, Dima, Nsairat, Hamdi, Odeh, Fadwa, Saleh, Mais, Jaber, Areej, Alshaer, Walhan, Al Bawab, Abeer, Mubarak, Mohammad S.

“…Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles…”
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Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin by Alshaer, Walhan, Alqudah, Dana A, Wehaibi, Suha, Abuarqoub, Duaa, Zihlif, Malek, Hatmal, Ma'mon M, Awidi, Abdalla

“…Combinatorial therapeutic strategies using siRNA and small molecules to eradicate tumors are emerging. Targeting multiple signaling pathways decreases the…”
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Gold Nanoparticles Ameliorate Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats by Aljabali, Alaa A A, Al-Trad, Bahaa, Gazo, Lina Al, Alomari, Ghada, Al Zoubi, Mazhar, Alshaer, Walhan, Al-Batayneh, Khalid, Kanan, Bahja, Pal, Kaushik, Tambuwala, Murtaza M.

“…•Gold nanoparticles (AuNPs) have anti-hyperglycemic effects in animal models of streptozotocin (STZ)-induced diabetes.•This study was designed to address the…”
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Gold-coated plant virus as computed tomography imaging contrast agent by Aljabali, Alaa A A, Zoubi, Mazhar S Al, Al-Batanyeh, Khalid M, Al-Radaideh, Ali, Obeid, Mohammad A, Al Sharabi, Abeer, Alshaer, Walhan, AbuFares, Bayan, Al-Zanati, Tasnim, Tambuwala, Murtaza M, Akbar, Naveed, Evans, David J

“…Chemical modification of the surface of viruses, both the interior and the exterior, imparts new functionalities, that have potential applications in…”
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Synthesis of novel benzothieno-[3,2’-f][1,3] oxazepines and their isomeric 2-oxo-2H-spiro[benzothiophene-3,3’-pyrrolines] via 1,4-dipolar cycloaddition reaction and their evaluation as cytotoxic anticancer leads by Al-Mahadeen, Mohammed M., Jaber, Areej M., Zahra, Jalal A., El-Abadelah, Mustafa M., Alshaer, Walhan, Taha, Mutasem O.

“…This study introduces a novel class of hybrid compounds, namely, benzothieno[3,2’- f ][1,3]oxazepines and their isomeric 2-oxo-2 H…”
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Downregulation of aquaporins and PI3K/AKT and upregulation of PTEN expression induced by the flavone scutellarein in human colon cancer cell lines by Tarawneh, Noor, Hamadneh, Lama, Alshaer, Walhan, Al Bawab, Abdel Qader, Bustanji, Yasser, Abdalla, Shtaywy

“…Scutellarein has an anticancer potential, but the pathway of its action has not been elucidated. This study investigated scutellarein efficacy against human…”
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Investigating the association of CD36 gene polymorphisms (rs1761667 and rs1527483) with T2DM and dyslipidemia: Statistical analysis, machine learning based prediction, and meta-analysis by Hatmal, Ma'mon M, Alshaer, Walhan, Mahmoud, Ismail S, Al-Hatamleh, Mohammad A. I, Al-Ameer, Hamzeh J, Abuyaman, Omar, Zihlif, Malek, Mohamud, Rohimah, Darras, Mais, Al Shhab, Mohammad, Abu-Raideh, Rand, Ismail, Hilweh, Al-Hamadi, Ali, Abdelhay, Ali

“…CD36 (cluster of differentiation 36) is a membrane protein involved in lipid metabolism and has been linked to pathological conditions associated with…”
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