Search Results - "Alseth, Ingrun"

Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21 by Yang, Mingyi, Luna, Luisa, Sørbø, Jan Gunnar, Alseth, Ingrun, Johansen, Rune F., Backe, Paul H., Danbolt, Niels C., Eide, Lars, Bjørås, Magnar

“…The oxidation resistance gene 1 (OXR1) prevents oxidative stress-induced cell death by an unknown pathway. Here, depletion of human OXR1 (hOXR1) sensitized…”
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Circular RNA Profile in Atherosclerotic Disease: Regulation during ST-Elevated Myocardial Infarction by Holme, Fredric A, Huse, Camilla, Kong, Xiang Yi, Broch, Kaspar, Gullestad, Lars, Anstensrud, Anne Kristine, Andersen, Geir Ø, Amundsen, Brage H, Kleveland, Ola, Quiles-Jimenez, Ana, Holm, Sverre, Aukrust, Pål, Alseth, Ingrun, Halvorsen, Bente, Dahl, Tuva B

“…Circular (circ) RNAs are non-coding RNAs with important functions in the nervous system, cardiovascular system, and cancer. Their role in atherosclerosis and…”
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ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA by Greiner-Tollersrud, Ole Kristian, Krausz, Máté, Boehler, Vincent, Polyzou, Aikaterini, Seidl, Maximilian, Spahiu, Ambra, Abdullah, Zeinab, Andryka-Cegielski, Katarzyna, Dominick, Felix Immunuel, Huebscher, Katrin, Goschin, Andreas, Smulski, Cristian R., Trompouki, Eirini, Link, Regina, Ebersbach, Hilmar, Srinivas, Honnappa, Marchant, Martine, Sogkas, Georgios, Staab, Dieter, Vågbø, Cathrine, Guerini, Danilo, Baasch, Sebastian, Latz, Eicke, Hartmann, Gunther, Henneke, Philippe, Geiger, Roger, Peng, Xiao P., Grimbacher, Bodo, Bartok, Eva, Alseth, Ingrun, Warncke, Max, Proietti, Michele

“…Although adenosine deaminase 2 (ADA2) is considered an extracellular ADA, evidence questions the physiological relevance of this activity. Our study reveals…”
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Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform by Berges, Natalia, Nawaz, Meh Sameen, Børresdatter Dahl, Tuva, Hagen, Lars, Bjørås, Magnar, Laerdahl, Jon K, Alseth, Ingrun

“…Endonuclease V (ENDOV) is a ribonuclease with affinity for inosine which is the deamination product of adenosine. The genomes of most organisms, including…”
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Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V by Dalhus, Bjørn, Alseth, Ingrun, Bjørås, Magnar

“…Deamination of the exocyclic amines in adenine, guanine and cytosine forms base lesions that may lead to mutations if not removed by DNA repair proteins…”
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Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules by Nawaz, Meh Sameen, Vik, Erik Sebastian, Berges, Natalia, Fladeby, Cathrine, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun

“…Endonuclease V (EndoV) is an enzyme with specificity for inosines in nucleic acids. Whereas the bacterial homologs are active on both DNA and RNA, the…”
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The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside by Grøsvik, Kristin, Tesfahun, Almaz Nigatu, Muruzábal-Lecumberri, Izaskun, Haugland, Gyri Teien, Leiros, Ingar, Ruoff, Peter, Kvaløy, Jan Terje, Knævelsrud, Ingeborg, Ånensen, Hilde, Alexeeva, Marina, Sato, Kousuke, Matsuda, Akira, Alseth, Ingrun, Klungland, Arne, Bjelland, Svein

“…The cellular methyl donor -adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with…”
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The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures by Fladeby, Cathrine, Vik, Erik Sebastian, Laerdahl, Jon K, Gran Neurauter, Christine, Heggelund, Julie E, Thorgaard, Eirik, Strøm-Andersen, Pernille, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun

“…Loss of amino groups from adenines in DNA results in the formation of hypoxanthine (Hx) bases with miscoding properties. The primary enzyme in Escherichia coli…”
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Structural Basis of DNA Loop Recognition by Endonuclease V by Rosnes, Ida, Rowe, Alexander D., Vik, Erik S., Forstrøm, Rune Johansen, Alseth, Ingrun, Bjørås, Magnar, Dalhus, Bjørn

“…The DNA repair enzyme endonuclease V (EndoV) recognizes and cleaves DNA at deaminated adenine lesions (hypoxanthine). In addition, EndoV cleaves DNA containing…”
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Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones by Korvald, Hanne, Mølstad Moe, Anne Margrethe, Cederkvist, F Henning, Thiede, Bernd, Laerdahl, Jon K, Bjørås, Magnar, Alseth, Ingrun

“…2-Oxoglutarate (2OG) dependent dioxygenases are ubiquitous iron containing enzymes that couple substrate oxidation to the conversion of 2OG to succinate and…”
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The Saccharomyces cerevisiae Homologues of Endonuclease III from Escherichia coli, Ntg1 and Ntg2, Are Both Required for Efficient Repair of Spontaneous and Induced Oxidative DNA Damage in Yeast by Alseth, Ingrun, Eide, Lars, Pirovano, Manuela, Rognes, Torbjørn, Seeberg, Erling, Bjørås, Magnar

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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new protein superfamily includes two novel 3‐methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD by Alseth, Ingrun, Rognes, Torbjørn, Lindbäck, Toril, Solberg, Inger, Robertsen, Kristin, Kristiansen, Knut Ivan, Mainieri, Davide, Lillehagen, Lucy, Kolstø, Anne‐Brit, Bjørås, Magnar

“…Soil bacteria are heavily exposed to environmental methylating agents such as methylchloride and may have special requirements for repair of alkylation damage…”
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Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis by Mol, Clifford D, Arvai, Andrew S, Slupphaug, Geir, Kavli, Bodil, Alseth, Ingrun, Krokan, Hans E, Tainer, John A

“…Crystal structures of the DNA repair enzyme human uracil-DNA glycosylase (UDG), combined with mutational analysis, reveal the structural basis for the…”
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Inosine in DNA and RNA by Alseth, Ingrun, Dalhus, Bjørn, Bjørås, Magnar

“…Deamination of the nucleobases in DNA and RNA is a result of spontaneous hydrolysis, endogenous or environmental factors as well as deaminase enzymes…”
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A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage by Osman, Fekret, Bjørås, Magnar, Alseth, Ingrun, Morland, Ingrid, McCready, S., Seeberg, Erling, Tsaneva, Irina

“…Summary Endonuclease III (Nth) enzyme from Escherichia coli is involved in base excision repair of oxidised pyrimidine residues in DNA. The Schizosaccharomyces…”
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Circular RNA profile in atherosclerosis and myocardial infarction by Holme, Fredric, Huse, Camilla, Kong, Xiang, Alseth, Ingrun, Broch, Kaspar, Gullestad, Lars, Aukrust, Pål, Halvorsen, Bente, Dahl, Tuva

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N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis by Quiles-Jiménez, Ana, Gregersen, Ida, Mittelstedt Leal de Sousa, Mirta, Abbas, Azhar, Kong, Xiang Yi, Alseth, Ingrun, Holm, Sverre, Dahl, Tuva B., Skagen, Karolina, Skjelland, Mona, Aukrust, Pål, Bjørås, Magnar, Halvorsen, Bente

“…More than 170 post-transcriptional RNA modifications regulate the localization, processing and function of cellular RNAs, and aberrant RNA modifications have…”
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Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies by Quiles-Jiménez, Ana, Dahl, Tuva B., Bjørås, Magnar, Alseth, Ingrun, Halvorsen, Bente, Gregersen, Ida

“…The global risk of cardiovascular disease, including ischemic disease such as stroke, remains high, and cardiovascular disease is the cause of one-third of all…”
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Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity by Herrera, Maria C, Chymkowitch, Pierre, Robertson, Joseph M, Eriksson, Jens, Bøe, Stig Ove, Alseth, Ingrun, Enserink, Jorrit M

“…Abstract tRNA genes are transcribed by RNA polymerase III (RNAPIII). During recent years it has become clear that RNAPIII activity is strictly regulated by the…”
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Endonuclease V cleaves at inosines in RNA by Sebastian Vik, Erik, Sameen Nawaz, Meh, Strøm Andersen, Pernille, Fladeby, Cathrine, Bjørås, Magnar, Dalhus, Bjørn, Alseth, Ingrun

“…Endonuclease V orthologues are highly conserved proteins found in all kingdoms of life. While the prokaryotic enzymes are DNA repair proteins for removal of…”
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