Search Results - "Alsenaidy, Mohammad A."

Advances in Oral Drug Delivery by Alqahtani, Mohammed S, Kazi, Mohsin, Alsenaidy, Mohammad A, Ahmad, Muhammad Z

“…The oral route is the most common route for drug administration. It is the most preferred route, due to its advantages, such as non-invasiveness, patient…”
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The status of licensed pharmacy workforce in Saudi Arabia: a 2030 economic vision perspective by AlRuthia, Yazed, Alsenaidy, Mohammad A, Alrabiah, Haitham K, AlMuhaisen, Abdullah, Alshehri, Mohammad

“…The economy of Saudi Arabia is currently undergoing a major transformation which will have an impact on employment in the pharmacy sector. However,…”
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Role of site-directed mutagenesis and adjuvants in the stability and potency of anthrax protective antigen by Dahhas, Mohammed Ali, Alsenaidy, Mohammad A.

“…Anthrax is a zoonotic infection caused by the gram-positive, aerobic, spore-forming bacterium Bacillus anthracis. Depending on the origin of the infection,…”
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Aggregation and conformational stability evaluation of myoglobin in the presence of ionic surfactant by Alsenaidy, Mohammad A.

“…Sodium lauroyl sarcosinate (SLS) is frequently used for the solubilization of inclusion bodies in vitro due to its structural similarity to lipid plasma…”
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Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology by Alalaiwe, Ahmed, Alsenaidy, Mohammad A, Almalki, Ziyad S, Fayed, Mohamed H

“…The availability of age-appropriate oral dosage forms for pediatric patients has remained a challenge. Orodispersible mini-tablets (ODMTs) are a promising…”
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Screening and identification of potential MERS-CoV papain-like protease (PLpro) inhibitors; Steady-state kinetic and Molecular dynamic studies by Ali Dahhas, Mohammed, M. Alkahtani, Hamad, Malik, Ajamaluddin, Almehizia, Abdulrahman A, Bakheit, Ahmed H., Akber Ansar, Siddique, AlAbdulkarim, Abdullah S., S.Alrasheed, Lamees, Alsenaidy, Mohammad A.

“…MERS-CoV belongs to the coronavirus group. Recent years have seen a rash of coronavirus epidemics. In June 2012, MERS-CoV was discovered in the Kingdom of…”
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Glycation Induced Generation of Amyloid Fibril Structures by Glucose Metabolites by Khan, Mohammad S, Rabbani, Nayyar, Tabrez, Shams, Islam, Badar Ul, Malik, Ajamaluddin, Ahmed, Anwar, Alsenaidy, Mohammad A, Alsenaidy, Abdulrahman M

“…The non-enzymatic reaction (glycation) of reducing sugars with proteins has received increased interest in dietary and therapeutic research lately. In the…”
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High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation by Alsenaidy, Mohammad A, Kim, Jae Hyun, Majumdar, Ranajoy, Weis, David D, Joshi, Sangeeta B, Tolbert, Thomas J, Middaugh, C Russell, Volkin, David B

“…The structural integrity and conformational stability of an IgG1 monoclonal antibody (mAb), after partial or complete enzymatic removal of the N-linked Fc…”
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Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles by Alsenaidy, Mohammad A, Jain, Nishant K, Kim, Jae H, Middaugh, C Russell, Volkin, David B

“…In this review, some of the challenges and opportunities encountered during protein comparability assessments are summarized with an emphasis on developing new…”
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Expression, Purification and Properties of Redox-Sensitive Eye Lens Zeta-Crystallin of Arabian Camel by Malik, Ajamaluddin, Rabbani, Mohammed, Rabbani, Nayyar, Al-Senaidy, Abdulrahman M, Alsenaidy, Mohammad A

“…The high protein concentration, unique composition and complex geometry of the lens makes it transparent. α-, β-, and γ-crystallins are present in all the…”
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Shortage of psychotropic medications in community pharmacies in Saudi Arabia: Causes and solutions by Al-Ruthia, Yazed Sulaiman, Mansy, Wael, Barasin, Mohammad, Ghawaa, Yazeed Mohammad, AlSultan, Mohammed, Alsenaidy, Mohammad A., Alhawas, Solaiman, AlGhadeer, Sultan

“…Background: Patients with mental disorders, such as depression and anxiety, who seek medical care in private psychiatric clinics in Riyadh, Saudi Arabia, have…”
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Molecular insight into binding behavior of polyphenol (rutin) with beta lactoglobulin: Spectroscopic, molecular docking and MD simulation studies by Al-Shabib, Nasser Abdulatif, Khan, Javed Masood, Malik, Ajamaluddin, Alsenaidy, Mohammad A., Rehman, Md Tabish, AlAjmi, Mohamed F., Alsenaidy, Abdulrahman M., Husain, Fohad Mabood, Khan, Rizwan Hasan

“…The interaction of natural polyphenolic compounds (rutin) with β-lactoglobulin (BLG) was carried out by using several optical spectroscopic (UV–visible…”
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Lignin nanoparticles as a promising vaccine adjuvant and delivery system for ovalbumin by Alqahtani, Mohammed S., Kazi, Mohsin, Ahmad, Muhammad Z., Syed, Rabbani, Alsenaidy, Mohammad A., Albraiki, Salem A.

“…Vaccination is the most effective strategy of preventing and treating infectious diseases and the most significant issue in the development of potent vaccines…”
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Biophysical evaluation of amyloid fibril formation in bovine cytochrome c by sodium lauroyl sarcosinate (sarkosyl) in acidic conditions by Alsenaidy, Mohammad A.

“…Surfactant-induced amyloid fibril formation in protein has a lot of association in the laboratory and industrial application. Sodium lauroyl sarcosinate…”
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Unraveling the molecular mechanism of the effects of sodium dodecyl sulfate, salts, and sugars on amyloid fibril formation in camel IgG by Ismael, Mohamad Alhasan, Khan, Javed Masood, Malik, Ajamaluddin, Alsenaidy, Mohammad A., Hidayathulla, Syed, Khan, Rizwan Hasan, Sen, Priyankar, Irfan, Mohammad, Alsenaidy, Abdulrahman M.

“…[Display omitted] •SDS is promoting amyloid fibril formation in camel IgG at pH 3.5.•SDS was unable to induce amyloid fibril in camel IgG at pH 7.4•Sulphate…”
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Cationic gemini surfactant (16-4-16) interact electrostatically with anionic plant lectin and facilitates amyloid fibril formation at neutral pH by Khan, Javed Masood, Khan, Mohd. Shahnawaz, Qadeer, Atiyatul, Alsenaidy, Mohammad A., Ahmed, Anwar, Al-Shabib, Nasser Abdulatif, Khan, Rizwan Hasan

“…[Display omitted] •Low concentrations of gemini surfactant induces amyloid fibril in Con A protein.•Higher concentrations of Gemini surfactant induces alpha…”
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Unveiling the stimulatory effects of tartrazine on human and bovine serum albumin fibrillogenesis: Spectroscopic and microscopic study by Al-Shabib, Nasser Abdulatif, Khan, Javed Masood, Alsenaidy, Mohammad A., Alsenaidy, Abdulrahman M., Khan, Mohd Shahnawaz, Husain, Fohad Mabood, Khan, Mohammad Rashid, Naseem, Mohammad, Sen, Priyankar, Alam, Parvez, Khan, Rizwan Hasan

“…Amyloid fibrils are playing key role in the pathogenesis of various neurodegenerative diseases. Generally anionic molecules are known to induce amyloid fibril…”
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Negatively charged food additive dye “Allura Red” rapidly induces SDS-soluble amyloid fibril in beta-lactoglobulin protein by Al-Shabib, Nasser Abdulatif, Khan, Javed Masood, Malik, Ajamaluddin, Alsenaidy, Abdulrahman M., Alsenaidy, Mohammad A., Husain, Fohad Mabood, Shamsi, Monis Bilal, Hidayathulla, Syed, Khan, Rizwan Hasan

“…•Allura red dye rapidly induces amyloid-like fibril in bovine beta lactoglobulin at acidic pH.•The electrostatic and hydrophobic interaction is mainly…”
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A quercetin-based flavanoid (rutin) reverses amyloid fibrillation in β-lactoglobulin at pH 2.0 and 358 K by Al-Shabib, Nasser Abdulatif, Khan, Javed Masood, Malik, Ajamaluddin, Sen, Priyankar, Alsenaidy, Mohammad A., Husain, Fohad Mabood, Alsenaidy, Abdulrahman M., Khan, Rizwan Hasan, Choudhry, Hani, Zamzami, Mazin A., Khan, Mohmmad Imran, Shahzad, Syed Ali

“…β-lactoglobulin (BLG) is a well characterized milk protein and a model for folding and aggregation studies. Rutin is a quercetin based-flavanoid and a famous…”
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pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI) by Khan, Javed Masood, Alsenaidy, Mohammad A., Khan, Mohd Shahnawaz, Sen, Priyankar, Khan, Rizwan Hasan, Fatima, Sadaf

“…Lima Bean Trypsin Inhibitor (LBTI) is 83 residues monomeric protein of 9.0 KDa, consisting of six antiparallel β-strands and can undergo concentration…”
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