Search Results - "Alsehli, Mosa"

Polymeric nanocarriers as stimuli-responsive systems for targeted tumor (cancer) therapy: Recent advances in drug delivery by Alsehli, Mosa

“…In the last decade, considerable attention has been devoted to the use of biodegradable polymeric materials as potential drug delivery carriers. However,…”
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Unimolecular Micelles from Randomly Grafted Arborescent Copolymers with Different Core Branching Densities: Encapsulation of Doxorubicin and In Vitro Release Study by Alsehli, Mosa, Gauthier, Mario

“…A series of amphiphilic arborescent copolymers of generations G1 and G2 with an arborescent poly(γ-benzyl L-glutamate) (PBG) core and poly(ethylene oxide)…”
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Development of Polyvinyl Alcohol/Kaolin Sponges Stimulated by Marjoram as Hemostatic, Antibacterial, and Antioxidant Dressings for Wound Healing Promotion by Tamer, Tamer M, Alsehli, Mosa H, Omer, Ahmed M, Afifi, Tarek H, Sabet, Maysa M, Mohy-Eldin, Mohamed S, Hassan, Mohamed A

“…The predominant impediments to cutaneous wound regeneration are hemorrhage and bacterial infections that lead to extensive inflammation with lethal impact. We…”
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A higher dose of PEGylated gold nanoparticles reduces the accelerated blood clearance phenomenon effect and induces spleen B lymphocytes in albino mice by Abu-Dief, Ahmed M., Alsehli, Mosa, Awaad, Aziz

“…Polyethylene glycol (PEG) is a multifunctional polymer that has many uses in medical and biological applications. Recently, PEG has been mainly used in…”
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Influence of the Core Branching Density on Drug Release from Arborescent Poly(γ-benzyl L-glutamate) End-Grafted with Poly(ethylene oxide) by Alsehli, Mosa, Gauthier, Mario

“…Amphiphilic dendritic copolymers of arborescent poly(γ-benzyl L-glutamate) (PBG) of generations G1 and G2, grafted at their chain ends with poly(ethylene…”
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Progress in Polymeric Nano-Medicines for Theranostic Cancer Treatment by Ali, Imran, Alsehli, Mosa, Scotti, Luciana, Tullius Scotti, Marcus, Tsai, Shang-Ting, Yu, Ruei-Siang, Hsieh, Ming Fa, Chen, Jung-Chih

“…Cancer is a life-threatening disease killing millions of people globally. Among various medical treatments, nano-medicines are gaining importance continuously…”
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DFT and In-silico Investigations, along with In-vitro Antitumor and Antimicrobial Assessments of Pharmacological Molecules by Alsehli, Mosa H, Seth, Daya S, El-Gaby, Mohamed S A, Okasha, Rawda M, Hagar, Mohamed, Afifi, Tarek H, Naqvi, Arshi

“…Molecules bearing an active methylene bridge are one of the most fruitful and remarkable precursors that have been incorporated into the synthetic strategy of…”
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Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, hCAII, and MMP-2 Inhibitors Based on Molecular Docking Assays by Alblewi, Fawzia F., Alsehli, Mosa H., Hritani, Zainab M., Eskandrani, Areej, Alsaedi, Wael H., Alawad, Majed O., Elhenawy, Ahmed A., Ahmed, Hanaa Y., El-Gaby, Mohamed S. A., Afifi, Tarek H., Okasha, Rawda M.

“…In this study, novel selective antitumor compounds were synthesized based on their fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A…”
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The bioreaction and immune responses of PEG-coated silica NPs and the role of the surface density coating after oral administration into mice by Abu-Dief, Ahmed M., Alsehli, Mosa, Awaad, Aziz

“…Silica nanoparticles (SiNPs) have many physical and chemical characteristics that make it useful tools for different medical and biological applications…”
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Exploring of N-phthalimide-linked 1,2,3-triazole analogues with promising -anti-SARS-CoV-2 activity: synthesis, biological screening, and molecular modelling studies by Aljuhani, Ateyatallah, Alsehli, Mosa, Seleem, Mohamed A, Alraqa, Shaya Y, Ahmed, Hany E A, Rezki, Nadjet, Aouad, Mohamed R

“…In this study, a library of phthalimide Schiff base linked to 1,4-disubstituted-1,2,3-triazoles was designed, synthesised, and characterised by different…”
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Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect by Alsehli, Mosa, Aljuhani, Ateyatallah, Ihmaid, Saleh K., El-Messery, Shahenda M., Othman, Dina I. A., El-Sayed, Abdel-Aziz A. A., Ahmed, Hany E. A., Rezki, Nadjet, Aouad, Mohamed R.

“…In this study, an efficient multistep synthesis of novel aromatic tricyclic hybrids incorporating different biological active moieties, such as…”
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Synthesis, Physicochemical Characterization using a Facile Validated HPLC Quantitation Analysis Method of 4-Chloro-phenylcarbamoyl-methyl Ciprofloxacin and Its Biological Investigations by Al-Hakkani, Mostafa F, Ahmed, Nourhan, Abbas, Alaa A, Hassan, Mohammad H. A, Aziz, Hossameldin A, Elshamsy, Ali M, Khalifa, Hazim O, Abdelshakour, Mohamed A, Saddik, Mohammed S, Elsayed, Mahmoud M. A, Sabet, Marwa A, El-Mokhtar, Mohamed A, Alsehli, Mosa, Amin, M. S, Abu-Dief, Ahmed M, Mohammed, Hamada H. H

“…A novel derivative of ciprofloxacin (Cpx) was synthesized and characterized using various analytical techniques, including FT-IR spectroscopy, UV-Vis…”
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Advances in Polymeric Colloids for Cancer Treatment by Ali, Imran, Althakfi, Sara H, Suhail, Mohammad, Locatelli, Marcello, Hsieh, Ming-Fa, Alsehli, Mosa, Hameed, Ahmed M

“…Polymer colloids have remarkable features and are gaining importance in many areas of research including medicinal science. Presently, the innovation of cancer…”
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Synthesis, Cytotoxic Activity, Crystal Structure, DFT, Molecular Docking Study of β-Enaminonitrile Incorporating 1H-Benzo[f]Chromene Moiety by Alsehli, Mosa H., Al-Harbi, Lali M., Okasha, Rawda M., Fouda, Ahmed M., Ghabbour, Hazem A., Amr, Abd El-Galil E., Elhenawy, Ahmed A., El-Agrody, Ahmed M.

“…In this work, we used microwave irradiation conditions to synthesize β-enaminonitrile (4), which was affirmed using single crystal X-ray diffraction and the…”
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Dielectric properties and AC conductivity for (Nix/Bentonite) composites by Abdel-Baset, T. A., Alsehli, Mosa, Bashal, Ali H.

“…We have studied the dielectric properties and electrical conductivity for pure bentonite (Ben) and Ben loaded with 1.0%, 3.0% and 10.0% Ni composition within…”
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Carboxymethyl cellulose/sodium alginate/chitosan biguanidine hydrochloride ternary system for edible coatings by Salama, Hend E., Abdel Aziz, Mohamed S., Alsehli, Mosa

“…Chitosan biguanidine hydrochloride (CBg) was prepared as a novel multifunctional biodegradable polymer with antimicrobial and excellent water-solubility…”
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Discovery of triaromatic flexible agents bearing 1,2,3-Triazole with selective and potent anti-breast cancer activity and CDK9 inhibition supported by molecular dynamics by Ihmaid, Saleh K., Aljuhani, Ateyatallah, Alsehli, Mosa, Rezki, Nadjet, Alawi, Ali, Aldhafiri, Ahmed J., Salama, Samir A., Ahmed, Hany E.A., Aouad, Mohamed R.

“…•Novel chromene-based analogues linked to 1,2,3-triazole fragment were synthesized.•The target components have been screened for anticancer activity and the…”
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Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5‑HT2A Receptor Inverse Agonists by Albujuq, Nader R., Meana, J. Javier, Diez-Alarcia, Rebeca, Muneta-Arrate, Itziar, Naqvi, Arshi, Althumayri, Khalid, Alsehli, Mosa

“…There is concern for important adverse effects with use of second-generation antipsychotics in Parkinson’s disease psychosis (PDP) and dementia-related…”
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Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel Pimavanserin-Based Analogues as Potential Serotonin 5-HT 2A Receptor Inverse Agonists by Albujuq, Nader R, Meana, J Javier, Diez-Alarcia, Rebeca, Muneta-Arrate, Itziar, Naqvi, Arshi, Althumayri, Khalid, Alsehli, Mosa

“…There is concern for important adverse effects with use of second-generation antipsychotics in Parkinson's disease psychosis (PDP) and dementia-related…”
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Tailoring, structural inspection of novel oxy and non-oxy metal-imine chelates for DNA interaction, pharmaceutical and molecular docking studies by Adam, Mohamed Shaker S., Abu-Dief, Ahmed M., Makhlouf, M.M., Shaaban, Saad, Alzahrani, Seraj O., Alkhatib, Fatmah, Masaret, Ghada S., Mohamed, Mamdouh A., Alsehli, Mosa, El-Metwaly, Nashwa M., Mohamad, Ahmad Desoky M.

“…Two mononuclear M(II) complexes (M = Ni2+ and ZrO2+ cations) of the imino-naphthalenol sodium sulfonate ligand (H2Lig) were prepared and characterized via…”
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