Search Results - "Alsallaq, Ramzi"

Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier by Cortez, Valerie, Boyd, David F., Crawford, Jeremy Chase, Sharp, Bridgett, Livingston, Brandi, Rowe, Hannah M., Davis, Amy, Alsallaq, Ramzi, Robinson, Camenzind G., Vogel, Peter, Rosch, Jason W., Margolis, Elisa, Thomas, Paul G., Schultz-Cherry, Stacey

“…Astroviruses are a global cause of pediatric diarrhea, but they are largely understudied, and it is unclear how and where they replicate in the gut. Using an…”
Get full text

Quantitative assessment of the impact of partially protective anti-schistosomiasis vaccines by Alsallaq, Ramzi A, Gurarie, David, Ndeffo Mbah, Martial, Galvani, Alison, King, Charles

“…Mass drug administration (MDA) of praziquantel has been the intervention of choice against schistosomiasis but with limited success in interrupting the…”
Get full text

The potential impact and cost of focusing HIV prevention on young women and men: A modeling analysis in western Kenya by Alsallaq, Ramzi A, Buttolph, Jasmine, Cleland, Charles M, Hallett, Timothy, Inwani, Irene, Agot, Kawango, Kurth, Ann E

“…We compared the impact and costs of HIV prevention strategies focusing on youth (15-24 year-old persons) versus on adults (15+ year-old persons), in a high-HIV…”
Get full text

Electrostatic rate enhancement and transient complex of protein-protein association by Alsallaq, Ramzi, Zhou, Huan-Xiang

“…The association of two proteins is bounded by the rate at which they, via diffusion, find each other while in appropriate relative orientations. Orientational…”
Get full text

Improved yield and accuracy for DNA extraction in microbiome studies with variation in microbial biomass by Davis, Amy, Kohler, Christina, Alsallaq, Ramzi, Hayden, Randall, Maron, Gabriela, Margolis, Elisa

“…A major challenge for microbiome studies is maintaining an even and accurate DNA extraction in the presence of samples with a wide range of bacterial content…”
Get full text

Towards an improved investment approach for an effective response to HIV/AIDS by Schwartländer, Bernhard, Dr, Stover, John, MA, Hallett, Timothy, PhD, Atun, Rifat, Prof, Avila, Carlos, MD, Gouws, Eleanor, PhD, Bartos, Michael, MEd, Ghys, Peter D, MD, Opuni, Marjorie, PhD, Barr, David, JD, Alsallaq, Ramzi, PhD, Bollinger, Lori, PhD, de Freitas, Marcelo, MD, Garnett, Geoffrey, Prof, Holmes, Charles, MD, Legins, Ken, MPH, Pillay, Yogan, PhD, Stanciole, Anderson Eduardo, PhD, McClure, Craig, PGCE, Hirnschall, Gottfried, MD, Laga, Marie, Prof, Padian, Nancy, PhD

“…Summary Substantial changes are needed to achieve a more targeted and strategic approach to investment in the response to the HIV/AIDS epidemic that will yield…”
Get full text

The design of schistosomiasis monitoring and evaluation programmes: The importance of collecting adult data to inform treatment strategies for Schistosoma mansoni by Toor, Jaspreet, Turner, Hugo C, Truscott, James E, Werkman, Marleen, Phillips, Anna E, Alsallaq, Ramzi, Medley, Graham F, King, Charles H, Anderson, Roy M

“…Monitoring and evaluation (M&E) programmes are used to collect data which are required to assess the impact of current interventions on their progress towards…”
Get full text

Understanding the potential impact of a combination HIV prevention intervention in a hyper-endemic community by Alsallaq, Ramzi A, Baeten, Jared M, Celum, Connie L, Hughes, James P, Abu-Raddad, Laith J, Barnabas, Ruanne V, Hallett, Timothy B

“…Despite demonstrating only partial efficacy in preventing new infections, available HIV prevention interventions could offer a powerful strategy when combined…”
Get full text

HIV treatment as prevention: considerations in the design, conduct, and analysis of cluster randomized controlled trials of combination HIV prevention by Boily, Marie-Claude, Mâsse, Benoît, Alsallaq, Ramzi, Padian, Nancy S, Eaton, Jeffrey W, Vesga, Juan F, Hallett, Timothy B

“…The rigorous evaluation of the impact of combination HIV prevention packages at the population level will be critical for the future of HIV prevention. In this…”
Get full text

Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventions by Hallett, Timothy B, Alsallaq, Ramzi A, Baeten, Jared M, Weiss, Helen, Celum, Connie, Gray, Ron, Abu-Raddad, Laith

“…Mathematical modelling has indicated that expansion of male circumcision services in high HIV prevalence settings can substantially reduce population-level HIV…”
Get more information

Population Level Impact of an Imperfect Prophylactic Vaccine for Herpes Simplex Virus-2 by Alsallaq, Ramzi A., Schiffer, Joshua T., Jr, Ira M. Longini, Wald, Anna, Corey, Lawrence, Abu-Raddad, Laith J.

“…Background: The continuation of developing Herpes simplex viras type-2 (HSV-2) prophylactic vaccines requires parallel mathematical modeling to quantify the…”
Get full text

HSV-2 serology can be predictive of HIV epidemic potential and hidden sexual risk behavior in the Middle East and North Africa by Abu-Raddad, Laith J, Schiffer, Joshua T, Ashley, Rhoda, Mumtaz, Ghina, Alsallaq, Ramzi A, Akala, Francisca Ayodeji, Semini, Iris, Riedner, Gabriele, Wilson, David

“…Abstract Background HIV prevalence is low in the Middle East and North Africa (MENA) region, though the risk or potential for further spread in the future is…”
Get full text

Quantitative assessment of the role of male circumcision in HIV epidemiology at the population level by Alsallaq, Ramzi A, Cash, Brianna, Weiss, Helen A, Longini, Ira M, Omer, Saad B, Wawer, Maria J, Gray, Ronald H, Abu-Raddad, Laith J

“…Abstract Objective Three recent randomized trials have shown that male circumcision (circumcision) reduces HIV incidence in heterosexual men by about 60%…”
Get full text

Are We on Our Way to Achieving the 2020 Goals for Schistosomiasis Morbidity Control Using Current World Health Organization Guidelines? by Toor, Jaspreet, Alsallaq, Ramzi, Truscott, James E, Turner, Hugo C, Werkman, Marleen, Gurarie, David, King, Charles H, Anderson, Roy M

“…Schistosomiasis remains an endemic parasitic disease affecting millions of people around the world. The World Health Organization (WHO) has set goals of…”
Get full text

Integrative Genome and Transcriptome Sequencing Analysis Indicates Genetic and Epigenetic Dysregulation in DS-AML by Ma, Xiaotu, Ries, Rhonda E, Tran, Quang, Liu, Yanling, Kolekar, Pandurang, Alsallaq, Ramzi, Liang, Zhikai, Shaw, Timothy, Devineni, Meghana, Deslattes Mays, Anne, Lau, Ching, Hitzler, Johann K., Meshinchi, Soheil

“…Down Syndrome related AML is driven by GATA1 alterations in patients with trisomy 21. Using exome or targeted sequencing, prior studies identified GATA1…”
Get full text

The new role of antiretrovirals in combination HIV prevention: a mathematical modelling analysis by CREMIN, Ide, ALSALLAQ, Ramzi, DYBUL, Mark, PIOT, Peter, GARNETT, Geoffrey, HALLETT, Timothy B

“…Antiretroviral drugs can reduce HIV acquisition among uninfected individuals (as pre-exposure prophylaxis: PrEP) and reduce onward transmission among infected…”
Get full text

13 ASTROVIRUS ALTERS THE GUT MUCUS BARRIER AND REDUCES COLONIZATION TO ENTEROPATHOGENIC E. COLI by Cortez, Valerie, Sharp, Bridgett, Livingston, Brandi, Rowe, Hannah, Alsallaq, Ramzi, Rosch, Jason, Margolis, Elisa, Schultz-Cherry, Stacey

Get full text

Application of Schistosomiasis Consortium for Operational Research and Evaluation Study Findings to Refine Predictive Modeling of Schistosoma mansoni and Schistosoma haematobium Control in Sub-Saharan Africa by King, Charles H, Yoon, Nara, Wang, Xiaoxia, Lo, Nathan C, Alsallaq, Ramzi, Ndeffo-Mbah, Martial, Li, Emily, Gurarie, David

“…An essential mission of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was to help inform global health practices related to…”
Get full text

13 ASTROVIRUS ALTERS THE GUT MUCUS BARRIER AND REDUCES COLONIZATION TO ENTEROPATHOGENIC E. COLI by Cortez, Valerie, Sharp, Bridgett, Livingston, Brandi, Rowe, Hannah, Alsallaq, Ramzi, Rosch, Jason, Margolis, Elisa, Schultz-Cherry, Stacey

“…Abstract Goblet cells, specialized epithelial cells that produce mucus, are essential for gut health. Dysfunctional goblet cell secretion can weaken the mucus…”
Get full text

Vancomycin Heteroresistance and Clinical Outcomes in Bloodstream Infections Caused by Coagulase-Negative Staphylococci by Dao, Tina H, Alsallaq, Ramzi, Parsons, Joshua B, Ferrolino, Jose, Hayden, Randall T, Rubnitz, Jeffrey E, Rafiqullah, Iftekhar M, Robinson, D Ashley, Margolis, Elisa B, Rosch, Jason W, Wolf, Joshua

“…Coagulase-negative staphylococci (CoNS) are a common etiology of serious and recurrent infections in immunocompromised patients. Although most isolates appear…”
Get full text