Prevalence and Risk Factors for Hypoparathyroidism Following Total Thyroidectomy in Taif City

Prevalence and Risk Factors for Hypoparathyroidism Following Total Thyroidectomy in Taif City

Background Postoperative hypoparathyroidism has been investigated in health records and surgical cohorts, but the results have been highly variable and imprecise. It is not clear how often endocrinologists encounter this hormone deficit in clinical practice. Thus, the aim of this study is to determi...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) Vol. 14; no. 12; p. e32460
Main Authors: Algethami, Rami F, Algarni, Faisal, Fallatah, Shouq, Almehmadi, Rahaf A, Aljuaid, Hatoon, Alsalem, Abdullah S, Mahfouz, Mohammad Eid M, Alosaimi, Majed
Format: Journal Article
Language:English
Published: United States Cureus Inc 12-12-2022
Cureus
Subjects:
Endocrinology/Diabetes/Metabolism
Females
General Surgery
Histopathology
Hospitals
Hypocalcemia
Lymphatic system
Otolaryngology
Patients
Risk factors
Statistical analysis
Surgeons
Thyroid gland
Thyroidectomy
Tumors
saudi arabia
prevalence
thyroidectomy
hypoparathyroidism
taif city
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Summary:Background Postoperative hypoparathyroidism has been investigated in health records and surgical cohorts, but the results have been highly variable and imprecise. It is not clear how often endocrinologists encounter this hormone deficit in clinical practice. Thus, the aim of this study is to determine the incidence of permanent hypoparathyroidism and the factors associated with it in a group of post-thyroidectomy patients followed at three tertiary care institutions in Taif city. Materials and Methods A retrospective cohort analysis was done to examine patients who had a total thyroidectomy in the city of Taif between January 1, 2015, and December 31, 2019. Patients were eligible for the study if they received total thyroidectomy, were above the age of 18 years, had surgical and pathological data available, and had been monitored in the same institution for at least a year after their thyroidectomy. Patients who did not return for follow-up care following surgery were excluded from the study. Results The incidence of hypoparathyroidism was 10.3%, and females had a higher prevalence (12.1%) than males (3.2%). In patients with two and three parathyroid glands, hypoparathyroidism was found to be more prevalent (33.3% and 25.5%) in permanent histological sections. There was no single independent risk factor for hypoparathyroidism according to a logistic regression model. Conclusion The incidence rate of hypoparathyroidism following total thyroidectomy was about 10.3%. There were no independent risk factors identified for hypoparathyroidism after total thyroidectomy. Permanent hypoparathyroidism severely affects the quality of life, and research should be done to prevent its incidence after thyroidectomy.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.32460