Search Results - "Alsalahat, Izzeddin"

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation by Talib, Wamidh H, Alsalahat, Izzeddin, Daoud, Safa, Abutayeh, Reem Fawaz, Mahmod, Asma Ismail

“…Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of…”
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Facile Conversion of the Quinone-Semicarbazone Chromophore of Naftazone into a Fluorescent Quinol-Semicarbazide: Kinetic Study and Analysis of Naftazone in Pharmaceuticals and Human Serum by Gamal, Mohammed, Ali, Hazim M., El-Shaheny, Rania, Naguib, Ibrahim A., Alsalahat, Izzeddin, El-Maghrabey, Mahmoud

“…Naftazone is a quinone-semi carbazone drug that possesses a strong orange color, and hence it was usually analyzed colorimetrically or by HPLC-UV. However,…”
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Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation by Elkomy, Mohammed H, Alruwaili, Nabil K, Elmowafy, Mohammed, Shalaby, Khaled, Zafar, Ameeduzzafar, Ahmad, Naveed, Alsalahat, Izzeddin, Ghoneim, Mohammed M, Eissa, Essam M, Eid, Hussein M

“…Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The characteristic of RA is gradual joint deterioration. Current RA treatment…”
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Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route by Abo El-Enin, Hadel A, Elkomy, Mohammed H, Naguib, Ibrahim A, Ahmed, Marwa F, Alsaidan, Omar A, Alsalahat, Izzeddin, Ghoneim, Mohammed M, Eid, Hussein M

“…This research aimed to design, optimize, and evaluate berberine-laden nanostructured lipid carriers overlaid with chitosan (BER-CTS-NLCs) for efficient brain…”
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Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats by Elkomy, Mohammed H., Eid, Hussein M., Elmowafy, Mohammed, Shalaby, Khaled, Zafar, Ameeduzzafar, Abdelgawad, Mohamed A., Rateb, Mostafa E., Ali, Mohammed R.A., Alsalahat, Izzeddin, Abou-Taleb, Heba A.

“…Diabetes mellitus is a life-threatening metabolic disease. At the moment, there is no effective treatment available to combat it. In this study, we aimed to…”
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Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis by Eissa, Essam M., Elkomy, Mohammed H., Eid, Hussein M., Ali, Adel A., Abourehab, Mohammed A. S., Alsubaiyel, Amal M., Naguib, Ibrahim A., Alsalahat, Izzeddin, Hassan, Amira H.

“…This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate…”
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Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation by Elkomy, Mohammed H., El Menshawe, Shahira F., Kharshoum, Rasha M., Abdeltwab, Amany M., Hussein, Raghda R. S., Hamad, Doaa S., Alsalahat, Izzeddin, Aboud, Heba M.

“…Asthma represents a globally serious non-communicable ailment with significant public health outcomes for both pediatrics and adults triggering vast morbidity…”
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Utilization of Polymeric Micelles as a Lucrative Platform for Efficient Brain Deposition of Olanzapine as an Antischizophrenic Drug via Intranasal Delivery by Abo El-Enin, Hadel A, Ahmed, Marwa F, Naguib, Ibrahim A, El-Far, Shaymaa W, Ghoneim, Mohammed M, Alsalahat, Izzeddin, Abdel-Bar, Hend Mohamed

“…Schizophrenia is a mental disorder characterized by alterations in cognition, behavior and emotions. Oral olanzapine (OZ) administration is extensively…”
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Greenness Assessment of HPLC Analytical Methods with Common Detectors for Assay of Paracetamol and Related Materials in Drug Products and Biological Fluids by Naguib, Ibrahim A, Majed, Meral, Albogami, Maram, Alshehri, Maram, Bukhari, Aseel, Alshabani, Hadeel, Alsalahat, Izzeddin, Abd-ElSalam, Heba-Alla H

“…Paracetamol is one of the most widely consumed analgesic and antipyretic medications worldwide. It is frequently analyzed in many quality control (QC)…”
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Evaluation of Greenness of LC-MS Chromatographic Methods for Simultaneous Analysis of Mixtures of Serotonin, Dopamine, Acetylcholine, GABA and Glutamate: AGREE Tool Application by Almalki, Atiah H., Alsalahat, Izzeddin, Alharthi, Muath A., Panda, Dibya Sundar, Almahri, Albandary, Naguib, Ibrahim A.

“…The analytical GREEnness metric (AGREE) tool is widely used as a reliable greenness assessment method for chromatographic analyses. The AGREE tool has the…”
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Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease by Alsalahat, Izzeddin, Al-Majdoub, Zubida M., Taha, Mutasem O., Barber, Jill, Aojula, Harmesh, Hodson, Nigel, Freeman, Sally

“…The pathogenesis of Alzheimer's disease (AD) is correlated with the misfolding and aggregation of amyloid-beta protein (Aβ). Here we report that the antibiotic…”
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Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats by Arafa, Waleed M., Elkomy, Mohammed H., Aboud, Heba M., Ali, Mona Ibrahim, Abdel Gawad, Samah S., Aboelhadid, Shawky M., Mahdi, Emad A., Alsalahat, Izzeddin, Abdel-Tawab, Heba

“…Hymenolepiasis represents a parasitic infection of common prevalence in pediatrics with intimidating impacts, particularly amongst immunocompromised patients…”
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Greenness Assessment of Chromatographic Methods Used for Analysis of Empagliflozin: A Comparative Study by Santali, Eman Y, Naguib, Ibrahim A, Alshehri, Abdullah M, Alzahrani, Yazeed A, Alharthi, Abdullah E, Alosaimi, Turki S, Alsayali, Bandar D, Alsalahat, Izzeddin, Almahri, Albandary, Abourehab, Mohammed A. S, Abdallah, Fatma F

“…The analytical chemistry community is attempting to incorporate green chemistry concepts in the development of analytical techniques to redefine analytical…”
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Green Assessment of Chromatographic Methods Used for the Analysis of Four Methamphetamine Combinations with Commonly Abused Drugs by Alharthy, Saif A., Alharthi, Muath A., Almalki, Sultan A., Alosaimi, Sattam H., Aqeel, Abdullah H., Altowairqi, Sultan A., Alsalahat, Izzeddin, Panda, Dibya Sundar, Alsheikh, Mona Y., Naguib, Ibrahim A.

“…Numerous agents with anxiolytic or stimulant effects have the potential to be overused, and their misuse is associated with serious side effects. In Saudi…”
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Targeting γ-aminobutyric acid (GABA) carriers to the brain: potential relevance as antiepileptic pro-drugs by Semreen, Mohammad H, El-Shorbagi, Abdel-Nasser, Al-Tel, Taleb H, Alsalahat, Izzeddin M M

“…The search for antiepileptic compounds with more selective activity continues to be an area of intensive investigation in medicinal chemistry…”
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Peppermint Aqueous Extract Counteracts Smooth Muscle Contraction in Rat Ileum by Alnnjeeli , Amal, Abuirmeileh , Amjad, Alkhodari , Abdulrahman, Naddaf , Ahmad, Alsalahat , Izzeddin, Talhouni , Ahmad

“…يستخدم النعناع على نطاق واسع لاضطرابات الجهاز الهضمي. و لم يتم حتى الآن دراسته على لفائف أمعاء الفئران الدقيقة. في هذا البحث، تمت دراسة تأثير مستخلص النعناع…”
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Resveratrol-mediated cleavage of amyloid β1–42 peptide: potential relevance to Alzheimer's disease by Al-Edresi, Sarmad, Alsalahat, Izzeddin, Freeman, Sally, Aojula, Harmesh, Penny, Jeffrey

“…Aggregation of amyloid β1–42 (Aβ1–42) peptide within the brain is considered one of the main causes of the neuropathological changes associated with…”
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A carvedilol analogue, VK‐II‐86, prevents hypokalaemia‐induced ventricular arrhythmia through novel multi‐channel effects by Robinson, Victoria M., Alsalahat, Izzeddin, Freeman, Sally, Antzelevitch, Charles, Barajas‐Martinez, Héctor, Venetucci, Luigi

“…Background and Purpose QT prolongation and intracellular Ca2+ loading with diastolic Ca2+ release via ryanodine receptors (RyR2) are the predominant mechanisms…”
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A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives by Ghoneim, Mohammed M., Abdelgawad, Mohamed A., Elkanzi, Nadia A. A., Parambi, Della Grace Thomas, Alsalahat, Izzeddin, Farouk, Amr, Bakr, Rania B.

“…Quinazoline and quinazolinone derivatives piqued medicinal chemistry interest in developing novel drug candidates owing to their pharmacological potential…”
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Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against IHymenolepis nana/I in Experimentally-Infected Rats by Arafa, Waleed M, Elkomy, Mohammed H, Aboud, Heba M, Ali, Mona Ibrahim, Abdel Gawad, Samah S, Aboelhadid, Shawky M, Mahdi, Emad A, Alsalahat, Izzeddin, Abdel-Tawab, Heba

“…Hymenolepiasis represents a parasitic infection of common prevalence in pediatrics with intimidating impacts, particularly amongst immunocompromised patients…”
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