Search Results - "Alsahli, Mohammed A"
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Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer
Published in Molecules (Basel, Switzerland) (09-07-2020)“…Epigallocatechin-3-gallate (EGCG), an active compound of green tea and its role in diseases cure and prevention has been proven. Its role in diseases…”
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Potential Therapeutic Targets of Resveratrol, a Plant Polyphenol, and Its Role in the Therapy of Various Types of Cancer
Published in Molecules (Basel, Switzerland) (21-04-2022)“…Cancer is among the most prominent causes of mortality worldwide. Different cancer therapy modes employed, including chemotherapy and radiotherapy, have been…”
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3
Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Cancer is the most commonly diagnosed type of disease and a major cause of death worldwide. Despite advancement in various treatment modules, there has been…”
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4
Myeloperoxidase as an Active Disease Biomarker: Recent Biochemical and Pathological Perspectives
Published in Medical sciences (Basel) (18-04-2018)“…Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is…”
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Potential Therapeutic Targets of Quercetin, a Plant Flavonol, and Its Role in the Therapy of Various Types of Cancer through the Modulation of Various Cell Signaling Pathways
Published in Molecules (Basel, Switzerland) (01-03-2021)“…Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most commonly derived from plants, fruits, and vegetables. Most of these…”
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The Potential Role of Apigenin in Cancer Prevention and Treatment
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Cancer is the leading cause of death worldwide. In spite of advances in the treatment of cancer, currently used treatment modules including chemotherapy,…”
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6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity
Published in Mediators of inflammation (2021)“…Diethylnitrosamine (DEN) is a well-known hepatocarcinogen, and its oral administration causes severe liver damage including cancer. DEN induces the…”
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8
A review on mechanism of inhibition of advanced glycation end products formation by plant derived polyphenolic compounds
Published in Molecular biology reports (2021)“…Advanced glycation end products (AGEs) are naturally occurring biomolecules formed by interaction of reducing sugars with biomolecules such as protein and…”
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Protective Effects of Thymoquinone, an Active Compound of Nigella sativa, on Rats with Benzo(a)pyrene-Induced Lung Injury through Regulation of Oxidative Stress and Inflammation
Published in Molecules (Basel, Switzerland) (27-05-2021)“…Benzopyrene [B(a)P] is a well-recognized environmental carcinogen, which promotes oxidative stress, inflammation, and other metabolic complications. In the…”
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Curcumin, an Active Constituent of Turmeric Spice: Implication in the Prevention of Lung Injury Induced by Benzo(a) Pyrene (BaP) in Rats
Published in Molecules (Basel, Switzerland) (07-02-2020)“…Benzo(a)pyrene (BaP) is a well-known carcinogen and enhances oxidative stress and apoptosis and also alters several molecular pathways. Curcumin is an active…”
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Garlic and its Active Compounds: A Potential Candidate in The Prevention of Cancer by Modulating Various Cell Signalling Pathways
Published in Anti-cancer agents in medicinal chemistry (01-01-2019)“…Cancer is a multi-factorial disease including alterations in the cell signalling pathways. Currently, several drugs are in use to treat cancer but such drugs…”
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Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression
Published in Molecules (Basel, Switzerland) (20-06-2020)“…Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are serious clinical complications with a high frequency of morbidity and mortality. The…”
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Regulation of Pro-Inflammatory Macrophage Polarization via Lipid Nanoparticles Mediated Delivery of Anti-Prostaglandin-E2 siRNA
Published in Current issues in molecular biology (20-12-2022)“…Pro-inflammatory macrophage polarization is crucial in acute inflammatory diseases like Acute lung injury (ALI), and acute respiratory distress syndrome…”
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Quercetin, a Plant Flavonol Attenuates Diabetic Complications, Renal Tissue Damage, Renal Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats
Published in Metabolites (15-01-2023)“…Diabetes mellitus is a metabolic syndrome characterized by increased glucose levels, oxidative stress, hyperlipidemia, and frequently decreased insulin levels…”
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Ginger: A Novel Strategy to Battle Cancer through Modulating Cell Signalling Pathways: A Review
Published in Current pharmaceutical biotechnology (2019)“…Numerous studies have been performed in understanding the development of cancer. Though, the mechanism of action of genes in the development of cancer remains…”
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Endoplasmic Reticulum Stress Provocation by Different Nanoparticles: An Innovative Approach to Manage the Cancer and Other Common Diseases
Published in Molecules (Basel, Switzerland) (16-11-2020)“…A proper execution of basic cellular functions requires well-controlled homeostasis including correct protein folding. Endoplasmic reticulum (ER) implements…”
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Therapeutic potential of thymoquinone liposomes against the systemic infection of Candida albicans in diabetic mice
Published in PloS one (27-12-2018)“…The present study was aimed to develop a liposomal formulation of thymoquinone (Lip-TQ) to treat Candida albicans infection in diabetic mice. Streptozotocin…”
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Tamarix articulata Induced Prevention of Hepatotoxicity Effects of In Vivo Carbon Tetrachloride by Modulating Pro-Inflammatory Serum and Antioxidant Enzymes to Reverse the Liver Fibrosis
Published in Antioxidants (15-09-2022)“…This study evaluates the hepatoprotective activity of a Tamarix articulata extract against carbon tetrachloride-mediated hepatotoxicity in Wistar rats. Our…”
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Comparison of the release of microRNAs and extracellular vesicles from platelets in response to different agonists
Published in Platelets (Edinburgh) (04-07-2018)“…On activation platelets release microRNAs and extracellular vesicles (EV) into circulation. The release of EV from platelets has been shown to be dependent on…”
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Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis
Published in Scientific reports (13-07-2022)“…Sepsis has affected millions of populations of all age groups, locations, and sexes worldwide. Immune systems, either innate or adaptive are dysregulated due…”
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