Search Results - "Alsaggaf, Azhaar"

Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review-Dedicated to the Memory of Professor Hanaa M. Rady by Radwan, Mohamed O, Abd-Alla, Howaida I, Alsaggaf, Azhaar T, El-Mezayen, Hatem, Abourehab, Mohammed A S, El-Beeh, Mohamed E, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako

“…In the last decade, gypsogenin has attracted widespread attention from medicinal chemists by virtue of its prominent anti-cancer potential. Despite its late…”
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Design and cytotoxic activity of thiazolidinones via one-pot, three component reaction under microwave and traditional method by Salah, Hanan, Elkanzi, Nadia A.A, Alsaggaf, Azhaar T, Moustafa, Alaa Y, Alkorbi, Faeza, Ali, Ali M

“…Treatment of sulfamethoxazole (SMZ ) (1) with different aromatic aldehydes 2a-f within few minutes (5-8 min) afforded the corresponding Schiff bases 3a-f which…”
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Design and evaluation of sulfadiazine derivatives as potent dual inhibitors of EGFRWT and EGFRT790M: integrating biological, molecular docking, and ADMET analysis by Abd El-Lateef, Hany M, Ezelarab, Hend A A, Ali, Ali M, Alsaggaf, Azhaar T, Mahdi, Wael A, Alshehri, Sultan, El Hamd, Mohamed A, Aboelez, Moustafa O

“…A series of derivatives (5–14) were synthesized through the diazotization of sulfadiazine with active methylene compounds. The chemical structures of these…”
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Design and evaluation of sulfadiazine derivatives as potent dual inhibitors of EGFR WT and EGFR T790M : integrating biological, molecular docking, and ADMET analysis by Abd El-Lateef, Hany M, Ezelarab, Hend A A, Ali, Ali M, Alsaggaf, Azhaar T, Mahdi, Wael A, Alshehri, Sultan, El Hamd, Mohamed A, Aboelez, Moustafa O

“…A series of derivatives (5-14) were synthesized through the diazotization of sulfadiazine with active methylene compounds. The chemical structures of these…”
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A New Family of Benzo[ h ]Chromene Based Azo Dye: Synthesis, In-Silico and DFT Studies with In Vitro Antimicrobial and Antiproliferative Assessment by Abd-El-Aziz, Alaa S, Alsaggaf, Azhaar, Assirey, Eman, Naqvi, Arshi, Okasha, Rawda M, Afifi, Tarek H, Hagar, Mohamed

“…The high biological activity of the chromene compounds coupled with the intriguing optical features of azo chromophores prompted our desire to construct novel…”
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Design, spectroscopic characterizations, and biological investigation of oxospiro[chromine-4,3-indolene]-based compounds as promising antiproliferative EGFR inhibitors and antimicrobial agents by Alzahrani, Abdullah Yahya Abdullah, Aboelez, Moustafa O, Kamel, Moumen S, Selim, Heba Mohammed Refat M, Alsaggaf, Azhaar T, Hamd, Mohammed A El, El-Remaily, Mahmoud Abd El Aleem Ali Ali

“…Utilizing microwave heating and an aqueous saturated solution of K CO as a catalyst, a rapidone-pot synthesis of oxospiro[chromene-4.3-indoline] derivatives…”
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Synthesis, Biological Assessment, and Structure Activity Relationship Studies of New Flavanones Embodying Chromene Moieties by Assirey, Eman, Alsaggaf, Azhaar, Naqvi, Arshi, Moussa, Ziad, Okasha, Rawda M, Afifi, Tarek H, Abd-El-Aziz, Alaa S

“…Novel flavanones that incorporate chromene motifs are synthesized via a one-step multicomponent reaction. The structures of the new chromenes are elucidated by…”
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Guanidine dicycloamine-based analogs: green chemistry synthesis, biological investigation, and molecular docking studies as promising antibacterial and antiglycation leads by El-Remaily, Mahmoud Abd El Aleem A A, Aboelez, Moustafa O, Ezelarab, Hend A A, Selim, Heba Mohammed Refat M, Taha, Enas A, Mohamed, Shaaban K, Soliman, Ahmed M, Abdallah, Mohamed S, Fawy, Mariam A, Hassany, Mohamed A, Ahmed, Nessar, Alsaggaf, Azhaar T, El Hamd, Mohamed A, Kamel, Moumen S

“…Dicyandiamide (DCD) reacted with amino acids 1a-f to produce biguanides 2 and 4 and guanidine pyrazolones 3, 5, 6, 7, and 8, according to the reaction. DCD…”
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Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity by McKenzie, Jordan A, Barghash, Reham F, Alsaggaf, Azhaar T, Kulkarni, Omkar, Boudreau, Kalun, Menard, Frederic, Neeland, Edward G, Klegeris, Andis

“…Neuroinflammation and microglia-mediated neurotoxicity contribute to the pathogenesis of a broad range of neurodegenerative diseases; therefore, identifying…”
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Antimicrobial and Antitumor Screening of Fluorescent 5,7‐Dihydroxy‐4‐Propyl‐2H‐Chromen‐2‐One Derivatives with Docking Studies by Abd‐El‐Aziz, Alaa S., Alsaggaf, Azhaar T, Okasha, Rawda M., Ahmed, Hany E. A., Bissessur, Rabin, Abdelghani, Amani A., Afifi, Tarek H.

“…A series of novel fluorescent 5,7‐dihydroxy‐4‐propyl‐2H‐chromen‐2‐one derivatives (2a–j) were synthesized and were found to absorb around 322 and 410 nm.All…”
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Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes IGame of Thrones/I on Anti-Cancer Therapy: A Critical Review—Dedicated to the Memory of Professor Hanaa M. Rady by Radwan, Mohamed O, Abd-Alla, Howaida I, Alsaggaf, Azhaar T, El-Mezayen, Hatem, Abourehab, Mohammed A. S, El-Beeh, Mohamed E, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako

“…In the last decade, gypsogenin has attracted widespread attention from medicinal chemists by virtue of its prominent anti-cancer potential. Despite its late…”
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Design, spectroscopic characterizations, and biological investigation of oxospirochromine-4,3-indolene-based compounds as promising antiproliferative EGFR inhibitors and antimicrobial agents by Alzahrani, Abdullah Yahya Abdullah, Aboelez, Moustafa O, Kamel, Moumen S, Selim, Heba Mohammed Refat M, Alsaggaf, Azhaar T, Hamd, Mohammed A El, El-Remaily, Mahmoud Abd El Aleem Ali Ali

“…Utilizing microwave heating and an aqueous saturated solution of K2CO3 as a catalyst, a rapidone-pot synthesis of oxospiro[chromene-4.3-indoline] derivatives…”
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