Search Results - "Alrumaihi, Faris"

A Comprehensive Computational Screening of Phytochemicals Derived from Saudi Medicinal Plants against Human CC Chemokine Receptor 7 to Identify Potential Anti-Cancer Therapeutics by Alrumaihi, Faris

“…Homeostatic trafficking of immune cells by CC chemokine receptor 7 (CCR7) keeps immune responses and tolerance in a balance. The involvement of this protein in…”
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A cheminformatics-biophysics correlate to identify promising lead molecules against matrix metalloproteinase-2 (MMP-2) enzyme: A promising anti-cancer target by Alrumaihi, Faris

“…Matrix metalloproteinase-2 (MMP-2) is an endopeptidase enzyme that is devoted to extracellular matrix proteins degradation. The enzyme is warranted as…”
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The Multi-Functional Roles of CCR7 in Human Immunology and as a Promising Therapeutic Target for Cancer Therapeutics by Alrumaihi, Faris

“…An important hallmark of the human immune system is to provide adaptive immunity against pathogens but tolerance toward self-antigens. The CC-chemokine…”
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Chemoinformatics and machine learning techniques to identify novel inhibitors of the lemur tyrosine kinase-3 receptor involved in breast cancer by Alrumaihi, Faris

“…Breast cancer is still the largest cause of cancer death in women, and around 70% of primary breast cancer patients are estrogen receptor (ER)-positive, which…”
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Putative role of 6-chogaol against tramadol-induced hepatotoxicity in albino rats via anti-inflammatory, antifibrotic, and antiapoptotic effects by Mousa, Ayman M., Alrumaihi, Faris A.

“…Tramadol is a commonly used drug to relieve pain and avoid premature ejaculation in males with hepatotoxic effects, and 6-chogaol has potent anti-inflammatory…”
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6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity by Alsahli, Mohammed A., Almatroodi, Saleh A., Almatroudi, Ahmad, Khan, Amjad Ali, Anwar, Shehwaz, Almutary, Abdulmajeed G., Alrumaihi, Faris, Rahmani, Arshad Husain

“…Diethylnitrosamine (DEN) is a well-known hepatocarcinogen, and its oral administration causes severe liver damage including cancer. DEN induces the…”
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Curcumin, an Active Constituent of Turmeric Spice: Implication in the Prevention of Lung Injury Induced by Benzo(a) Pyrene (BaP) in Rats by Almatroodi, Saleh A, Alrumaihi, Faris, Alsahli, Mohammed A, Alhommrani, Mazen Fahad, Khan, Arif, Rahmani, Arshad Husain

“…Benzo(a)pyrene (BaP) is a well-known carcinogen and enhances oxidative stress and apoptosis and also alters several molecular pathways. Curcumin is an active…”
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Pharmacological and therapeutic potential of neem (Azadirachta indica) by Rahmani, Arshad, Almatroudi, Ahmad, Alrumaihi, Faris, Khan, Amjad

“…Azadirachta indica, a member of the Meliaceae family, is commonly known as neem and its role in disease cure has been documented. Different parts of this tree…”
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Multiple roles for basement membrane proteins in cancer progression and EMT by Banerjee, Samarpita, Lo, Wen-Cheng, Majumder, Payel, Roy, Debleena, Ghorai, Mimosa, Shaikh, Nusrat K., Kant, Nishi, Shekhawat, Mahipal S., Gadekar, Vijaykumar Shivaji, Ghosh, Suchanda, Bursal, Ercan, Alrumaihi, Faris, Dubey, Navneet Kumar, Kumar, Sanjay, Iqbal, Danish, Alturaiki, Wael, Upadhye, Vijay Jagdish, Jha, Niraj Kumar, Dey, Abhijit, Gundamaraju, Rohit

“…Metastasis or the progression of malignancy poses a major challenge in cancer therapy and is the principal reason for increased mortality. The…”
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Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways by Almatroudi, Ahmad, Allemailem, Khaled S, Alwanian, Wanian M, Alharbi, Basmah F, Alrumaihi, Faris, Khan, Amjad Ali, Almatroodi, Saleh A, Rahmani, Arshad Husain

“…Cancer is the principal cause of death and its incidence is increasing continuously worldwide. Various treatment approaches are in practice to treat cancer,…”
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Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis by Sadaqat, Muhammad, Qasim, Muhammad, Tahir ul Qamar, Muhammad, Masoud, Muhammad Shareef, Ashfaq, Usman Ali, Noor, Fatima, Fatima, Kinza, Allemailem, Khaled S., Alrumaihi, Faris, Almatroudi, Ahmad

“…Liver cancer is a malignant tumor that grows on the surface or inside the liver. The leading cause is a viral infection with hepatitis B or C virus. Natural…”
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Pharmacological Potential of Kaempferol, a Flavonoid in the Management of Pathogenesis via Modulation of Inflammation and Other Biological Activities by Alrumaihi, Faris, Almatroodi, Saleh A, Alharbi, Hajed Obaid A, Alwanian, Wanian M, Alharbi, Fadiyah A, Almatroudi, Ahmad, Rahmani, Arshad Husain

“…Natural products and their bioactive compounds have been used for centuries to prevent and treat numerous diseases. Kaempferol, a flavonoid found in…”
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Ginger: A Novel Strategy to Battle Cancer through Modulating Cell Signalling Pathways: A Review by Almatroudi, Ahmad, Alsahli, Mohammed A, Alrumaihi, Faris, Allemailem, Khaled S, Rahmani, Arshad H

“…Numerous studies have been performed in understanding the development of cancer. Though, the mechanism of action of genes in the development of cancer remains…”
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Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management by Allemailem, Khaled S, Almatroodi, Saleh A, Almatroudi, Ahmad, Alrumaihi, Faris, Al Abdulmonem, Waleed, Al-Megrin, Wafa Abdullah I, Aljamaan, Adel Nasser, Rahmani, Arshad Husain, Khan, Amjad Ali

“…The innovative advances in transforming clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) into different variants…”
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Pan-Genome Analysis of Oral Bacterial Pathogens to Predict a Potential Novel Multi-Epitopes Vaccine Candidate by Rida, Tehniyat, Ahmad, Sajjad, Ullah, Asad, Ismail, Saba, Tahir ul Qamar, Muhammad, Afsheen, Zobia, Khurram, Muhammad, Saqib Ishaq, Muhammad, Alkhathami, Ali G., Alatawi, Eid A., Alrumaihi, Faris, Allemailem, Khaled S.

“…Porphyromonas gingivalis is a Gram-negative anaerobic bacterium, mainly present in the oral cavity and causes periodontal infections. Currently, no licensed…”
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Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols by Iftikhar, Arslan, Nausheen, Rimsha, Muzaffar, Humaira, Naeem, Muhammad Ahsan, Farooq, Muhammad, Khurshid, Mohsin, Almatroudi, Ahmad, Alrumaihi, Faris, Allemailem, Khaled S, Anwar, Haseeb

“…Honey is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the…”
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Exploring the role of miR-200 family in regulating CX3CR1 and CXCR1 in lung adenocarcinoma tumor microenvironment: implications for therapeutic intervention by Sharma, Archana, Singh, Prithvi, Jha, Rishabh, Almatroodi, Saleh A., Alrumaihi, Faris, Rahmani, Arshad Husain, Alharbi, Hajed Obaid, Dohare, Ravins, Syed, Mansoor Ali

“…Lung adenocarcinoma (LUAD) is the most common malignant subtype of lung cancer (LC). miR-200 family is one of the prime miR regulators of…”
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In Silico Mining of Terpenes from Red-Sea Invertebrates for SARS-CoV-2 Main Protease (M pro ) Inhibitors by Ibrahim, Mahmoud A A, Abdelrahman, Alaa H M, Mohamed, Tarik A, Atia, Mohamed A M, Al-Hammady, Montaser A M, Abdeljawaad, Khlood A A, Elkady, Eman M, Moustafa, Mahmoud F, Alrumaihi, Faris, Allemailem, Khaled S, El-Seedi, Hesham R, Paré, Paul W, Efferth, Thomas, Hegazy, Mohamed-Elamir F

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for the COVID-19 pandemic, which generated more than 1.82 million deaths in…”
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Bioinspired Green Synthesis of Zinc Oxide Nanoparticles from a Native Bacillus cereus Strain RNT6: Characterization and Antibacterial Activity against Rice Panicle Blight Pathogens Burkholderia glumae and B. gladioli by Ahmed, Temoor, Wu, Zhifeng, Jiang, Hubiao, Luo, Jinyan, Noman, Muhammad, Shahid, Muhammad, Manzoor, Irfan, Allemailem, Khaled S, Alrumaihi, Faris, Li, Bin

“…and are seed-borne rice pathogens that cause bacterial panicle blight (BPB) disease, resulting in huge rice yield losses worldwide. However, the excessive use…”
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Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways by Rahmani, Arshad Husain, Almatroudi, Ahmad, Allemailem, Khaled S, Alwanian, Wanian M, Alharbi, Basmah F, Alrumaihi, Faris, Khan, Amjad Ali, Almatroodi, Saleh A

“…Cancer is a major public health concern worldwide and main burden of the healthcare system. Regrettably, most of the currently used cancer treatment approaches…”
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