Search Results - "Alred, Erik J"

Mutations Alter RNA-Mediated Conversion of Human Prions by Alred, Erik J, Lodangco, Izra, Gallaher, Jennifer, Hansmann, Ulrich H.E

“…Prion diseases are connected with self-replication and self-propagation of misfolded proteins. The rate-limiting factor is the formation of the initial seed…”
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Molecular dynamics simulations of early steps in RNA‐mediated conversion of prions by Alred, Erik J., Nguyen, Michael, Martin, Maggie, Hansmann, Ulrich H. E.

“…The rate‐limiting step in prion diseases is the initial transition of a prion protein from its native form into a mis‐folded state in which the protein not…”
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On the lack of polymorphism in Aβ‐peptide aggregates derived from patient brains by Alred, Erik J., Phillips, Malachi, Berhanu, Workalemahu M., Hansmann, Ulrich H. E.

“…The amyloid beta (Aβ) oligomers and fibrils that are found in neural tissues of patients suffering from Alzheimer's disease may either cause or contribute to…”
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On the lack of polymorphism in A[beta]-peptide aggregates derived from patient brains by Alred, Erik J, Phillips, Malachi, Berhanu, Workalemahu M, Hansmann, Ulrich H E

“…The amyloid beta (A[beta]) oligomers and fibrils that are found in neural tissues of patients suffering from Alzheimer's disease may either cause or contribute…”
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Stability of Osaka Mutant and Wild-Type Fibril Models by Berhanu, Workalemahu M, Alred, Erik J, Hansmann, Ulrich H. E

“…Single amino acid mutations in amyloid-beta (Aβ) peptides can lead to early onset and increased severity of Alzheimer’s disease. An example is the Osaka…”
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Stability of Iowa mutant and wild type Aβ-peptide aggregates by Alred, Erik J, Scheele, Emily G, Berhanu, Workalemahu M, Hansmann, Ulrich H E

“…Recent experiments indicate a connection between the structure of amyloid aggregates and their cytotoxicity as related to neurodegenerative diseases. Of…”
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COMPARATIVE STABILITY ANALYSIS OF D23N MUTATED Aβ by ERIK J. ALRED, EMILY G. SCHEELE, WORKALEMAHU M. BERHANU, ULRICH H. E. HANSMANN

“…Amyloid β (Aβ) is the subject of numerous studies due to its link to the devastating Alzheimer’s disease and it exists in a parallel structure in fibril…”
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