Search Results - "Alrasheed, M M"
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Sitagliptin Mitigates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Type 2 Diabetes: Possible Role of PTP1B/JAK-STAT Pathway
Published in International journal of molecular sciences (31-03-2023)“…Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus. This study examined the therapeutic effects of sitagliptin, a dipeptidyl…”
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Sleep disturbances during the COVID-19 pandemic: A systematic review, meta-analysis, and meta-regression
Published in Sleep medicine reviews (01-04-2022)“…This systematic review and meta-analysis evaluated the extent of sleep disturbances during the COVID-19 pandemic. Eleven databases and six preprint…”
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TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study
Published in Saudi pharmaceutical journal (01-11-2022)“…The role of thyroid-stimulating hormone in the pathogenesis of thyroid cancer is not yet fully explored. This study aimed to evaluate the role of the TSH-β…”
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α1A Adrenoreceptor blockade attenuates myocardial infarction by modulating the integrin-linked kinase/TGF-β/Smad signaling pathways
Published in BMC cardiovascular disorders (24-03-2023)“…Myocardial infarction (MI) is considered a public health problem. According to the World Health Organization, MI is a leading cause of death and comorbidities…”
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The Prevalence of Psychological Distress and Its Relationship to Sleep Quality in Saudi Arabia's General Population During the COVID-19 Pandemic
Published in Frontiers in psychiatry (03-02-2022)“…We aimed to examine the effect of the COVID-19 pandemic and associated mitigation measures on sleep quality and psychological distress in Saudi Arabia…”
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Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
Published in Epidemiology and infection (01-01-2019)“…The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors…”
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Liraglutide Attenuates Diabetic Cardiomyopathy via the ILK/PI3K/AKT/PTEN Signaling Pathway in Rats with Streptozotocin-Induced Type 2 Diabetes Mellitus
Published in Pharmaceuticals (Basel, Switzerland) (01-03-2024)“…One of the possible candidates for the treatment of diabetic cardiomyopathy is liraglutide, a glucagon-like peptide-1 receptor (GLP1R) agonist. In this study,…”
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Prevalence and Pattern of Mandibular Condensing Osteitis Lesions in Saudi Population at Qassim Region
Published in Journal of pharmacy & bioallied science (01-07-2024)“…Condensing osteitis (CO) is a common radiopaque lesion observed in the jaws, often detected incidentally on panoramic radiographs. Understanding the prevalence…”
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Role of the integrin-linked kinase/TGF-β/SMAD pathway in sitagliptin-mediated cardioprotective effects in a rat model of diabetic cardiomyopathy
Published in Journal of pharmacy and pharmacology (06-01-2024)“…Abstract Objectives Diabetic cardiomyopathy is a known complication of diabetes mellitus. Herein, we aimed to determine whether glycemic control mediated by…”
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Quality of Life, Fatigue, and Physical Symptoms Post-COVID-19 Condition: A Cross-Sectional Comparative Study
Published in Healthcare (Basel) (05-06-2023)“…The magnitude of post-COVID-19 syndrome was not thoroughly investigated. This study evaluated the quality of life and persistence of fatigue and physical…”
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Analysis of the molecular and behavioral effects of acute social isolation on rats
Published in Behavioural brain research (13-01-2020)“…The mechanism underlying depression, anxiety, and stress-related psychiatric disorders is far from understood. The utilization of animal models of anxiety and…”
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Medication adherence, depression and disease activity among patients with systemic lupus erythematosus
Published in Lupus (01-02-2018)“…Introduction Medication non-adherence is an important cause of treatment failure among patients with systemic lupus erythematosus (SLE). Depression is a common…”
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Examining bedtime procrastination, study engagement, and studyholism in undergraduate students, and their association with insomnia
Published in Frontiers in psychology (17-01-2023)“…Compulsive overstudying, known as studyholism, is an emerging behavioral addiction. In this study, we examine the prevalence of, and the relationships between,…”
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Cardioprotective Effects of the GRK2 Inhibitor Paroxetine on Isoproterenol-Induced Cardiac Remodeling by Modulating NF-κB Mediated Prohypertrophic and Profibrotic Gene Expression
Published in International journal of molecular sciences (08-12-2023)“…Pathological cardiac remodeling is associated with cardiovascular disease and can lead to heart failure. Nuclear factor-kappa B (NF-κB) is upregulated in the…”
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Feasibility, and barriers to use escitalopram in functional gastrointestinal disorders
Published in Frontiers in pharmacology (22-05-2023)“…The feasibility and barriars of escitalopram use in patients with functional gastrointestinal disorders (FGIDs) are still debated. We aimed to evaluate the…”
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The role of CDKN2B in cardiovascular risk in ethnic Saudi Arabs: A validation study
Published in Gene (05-10-2018)“…Genome-wide association studies (GWASs) have yielded a wealth of information furnishing support for the variability in genetic predisposition to disease…”
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Arab Women Adherence to the Mediterranean Diet and Insomnia
Published in Medicina (Kaunas, Lithuania) (23-12-2021)“…Sleeping difficulties affect the overall health, nutrition, and wellbeing. The Mediterranean diet has proven effective in improving the quality of life and…”
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Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 Cells
Published in International journal of molecular sciences (01-06-2020)“…Accumulating evidence indicates that statins reduce the risk of different cancers and inhibit the proliferation of liver cancer cells. This study aims to…”
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Recording type 2 diabetes mellitus in a standardised central Saudi database: a retrospective validation study
Published in BMJ open (21-03-2023)“…ObjectivesThis study was conducted to assess the validity of recording (and the original diagnostic practice) of type 2 diabetes mellitus at a hospital whose…”
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A study of the role of DIO1 and DIO2 polymorphism in thyroid cancer and drug response to therapy in the Saudi population
Published in Saudi pharmaceutical journal (01-09-2019)“…Deiodinases comprise a group of selenoproteins that regulate the bioavailability of active thyroid hormones (TH) in a time and tissue specific fashion. They…”
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