Search Results - "Alqurshi, Abdulmalik"

Investigating the impact of COVID-19 lockdown on pharmaceutical education in Saudi Arabia – A call for a remote teaching contingency strategy by Alqurshi, Abdulmalik

“…COVID-19 lockdown has forced pharmacy education to be conducted remotely for approximately half of the second semester in the year 2019/2020. This sudden shift…”
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Household storage of pharmaceutical products in Saudi Arabia; A call for utilising smart packaging solutions by Alqurshi, Abdulmalik

“…Limited information is known about the storage conditions of medicinal products post-dispensing in Saudi Arabia (SA). The particularly hot and humid climate in…”
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Boosting Tadalafil Bioavailability via Sono-Assisted Nano-Emulsion-Based Oral Jellies: Box-Behnken Optimization and Assessment by Ali, Hany S M, Ahmed, Sameh A, Alqurshi, Abdulmalik A, Alalawi, Ali M, Shehata, Ahmed M, Alahmadi, Yaser M

“…Tadalafil (TAD) is a poorly soluble, phosphodiesterase inhibitor used to treat erectile dysfunction. The primary goal of this project was to prepare…”
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In-situ freeze-drying - forming amorphous solids directly within capsules: An investigation of dissolution enhancement for a poorly soluble drug by Alqurshi, Abdulmalik, Chan, K. L. Andrew, Royall, Paul G.

“…Conversion into the amorphous form enhances the dissolution of poorly soluble drugs, however the barrier to market for medicines containing an amorphous drug…”
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Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing by Ali, Hany S M, Ahmed, Sameh A, Alqurshi, Abdulmalik A, Alalawi, Ali M, Shehata, Ahmed M, Alahmadi, Yaser M

“…This research aimed to develop innovative self-nanoemulsifying chewable tablets (SNECT) to increase oral bioavailability of tadalafil (TDL), a nearly insoluble…”
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Fabric phase sorptive extraction coupled with UPLC-ESI-MS/MS method for fast and sensitive quantitation of tadalafil in a bioequivalence study by Ahmed, Sameh A., Alalawi, Ali M., Shehata, Ahmed M., Alqurshi, Abdulmalik A., Alahmadi, Yaser M., S. M. Ali, Hany

“…The current study coupled fabric phase sorptive extraction (FPSE) with ultraperformance liquid chromatography method with electrospray ionization and tandem…”
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Engineering of solidified glyburide nanocrystals for tablet formulation via loading of carriers: downstream processing, characterization, and bioavailability by Ali, Hany S M, Hanafy, Ahmed F, Alqurshi, Abdulmalik

“…Presenting poorly water-soluble drugs as nanoparticles has shown to be an effective technique in enhancing drug dissolution rate, intrinsic solubility, and…”
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Development of a chromatographic method with multi-criteria decision making design for simultaneous determination of nifedipine and atenolol in content uniformity testing by Ahmed, Sameh, Alqurshi, Abdulmalik, Mohamed, Abdel-Maaboud Ismail

“…A new robust and reliable high-performance liquid chromatography (HPLC) method with multi-criteria decision making (MCDM) approach was developed to allow…”
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In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles by Hashem, Fahima M, Nasr, Mohamed, Khairy, Ahmed, Alqurshi, Abdulmalik

“…Purpose: The objective of this work was to formulate a delivery system of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate (CS-DS) nanoparticles, and…”
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Naloxone without the needle − systematic review of candidate routes for non-injectable naloxone for opioid overdose reversal by Strang, John, McDonald, Rebecca, Alqurshi, Abdulmalik, Royall, Paul, Taylor, David, Forbes, Ben

“…Highlights • Deaths from opioid overdose can be prevented by prompt injection of the opiate antagonist naloxone. • After 40 years of injection-based naloxone,…”
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Digital Image Disintegration Analysis: a Novel Quality Control Method for Fast Disintegrating Tablets by Malallah, Osamah, Rashid, Zara, Li, Chee Lok, Alqurshi, Abdulmalik, Alhanan, Mohamed A., Forbes, Ben, Royall, Paul G.

“…Measuring tablet disintegration is essential for quality control purposes; however, no established method adequately accounts for the timeframe or small…”
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Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles by Hanafy, Ahmed F, Abdalla, Ahmed M, Guda, Tawheda K, Gabr, Khairy E, Royall, Paul G, Alqurshi, Abdulmalik

“…Conventional topical ophthalmic aqueous solutions and suspensions are often associated with low bioavailability and high administration frequency, pulsatile…”
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Antibacterial, antibiofilm and molecular modeling study of some antitumor thiazole based chalcones as a new class of DHFR inhibitors by Alrohily, Waad D., Habib, Mahmoud E., El-Messery, Shahenda M., Alqurshi, Abdulmalik, El-Subbagh, Hussein, Habib, El-Sayed E.

“…Some synthesized antitumor derivatives of thiazole based chalcones including thiazolo[2,3-b]quinazoline and pyrido[4,3-d]thiazolo[3,2-a]pyrimidine analogues…”
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Solid-state epimerisation and disproportionation of pilocarpine HCl: Why we need a 5-stage approach to validate melting point measurements for heat-sensitive drugs by Malallah, Osamah S., Hammond, Basilia, Al-Adhami, Taha, Buanz, Asma, Alqurshi, Abdulmalik, Carswell, William D., Rahman, Khondaker Miraz, Forbes, Ben, Royall, Paul G.

“…[Display omitted] Melting points for new drugs are reported in regulatory documents, e.g. investigational brochures, and frequently in published research;…”
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In vitro cytotoxicity and transfection efficiency of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate nanoparticles by Hashem, Fahima M, Nasr, Mohamed, Khairy, Ahmed, Alqurshi, Abdulmalik

“…The objective of this work was to formulate a delivery system of pDNA encoded p53 gene-loaded chitosan-sodium deoxycholate (CS-DS) nanoparticles, and to…”
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Amorphous Formulation and in Vitro Performance Testing of Instantly Disintegrating Buccal Tablets for the Emergency Delivery of Naloxone by Alqurshi, Abdulmalik, Kumar, Zahrae, McDonald, Rebecca, Strang, John, Buanz, Asma, Ahmed, Shagufta, Allen, Elizabeth, Cameron, Peter, Rickard, James A, Sandhu, Verity, Holt, Chris, Stansfield, Rebecca, Taylor, David, Forbes, Ben, Royall, Paul G

“…The aim of this study was to develop a freeze-dried buccal tablet for the rapid delivery of naloxone in opioid overdose. The tablet composition was optimized…”
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Design of freeze-dried formulations for the enhancement of drug release by Alqurshi, Abdulmalik Abdulrahman M

“…A commonly used approach for the improvement of dissolution and disintegration is to render a poorly soluble drug into its amorphous or disordered form…”
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