Search Results - "Alqahtani, Ali S."
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Cytotoxic Evaluation and Anti-Angiogenic Effects of Two Furano-Sesquiterpenoids from Commiphora myrrh Resin
Published in Molecules (Basel, Switzerland) (13-03-2020)“…resin (Myrrh) has been used in traditional Arabic medicine to treat various inflammatory diseases. Two furano-sesquiterpenoids, 2-methoxyfuranodiene (CM1) and…”
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In Vitro Alpha-Amylase and Alpha-Glucosidase Inhibitory Activity and In Vivo Antidiabetic Activity of Withania frutescens L. Foliar Extract
Published in Molecules (Basel, Switzerland) (08-01-2021)“…L. is a wild perennial woody plant used by the local population for diverse therapeutic purposes. This work aims to study for the first time the potential…”
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3
Chitosan-Coated Solid Lipid Nanoparticles as an Efficient Avenue for Boosted Biological Activities of Aloe perryi : Antioxidant, Antibacterial, and Anticancer Potential
Published in Molecules (Basel, Switzerland) (19-04-2023)“…(ALP) is an herb that has several biological activities such as antioxidant, antibacterial, and antitumor effects and is frequently used to treat a wide range…”
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4
Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins
Published in Journal of Traditional and Complementary Medicine (01-03-2021)“…Background and aim: COVID-19 emerged by the end of 2019 in Wuhan, China. It spreaded and became a public health emergency all over the world by mid of April…”
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Determination of Phenolic Compounds in Various Propolis Samples Collected from an African and an Asian Region and Their Impact on Antioxidant and Antibacterial Activities
Published in Molecules (Basel, Switzerland) (29-07-2021)“…The biological activities of propolis samples are the result of many bioactive compounds present in the propolis. The aim of the present study was to determine…”
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Alpha-Amylase and Alpha-Glucosidase Enzyme Inhibition and Antioxidant Potential of 3-Oxolupenal and Katononic Acid Isolated from Nuxia oppositifolia
Published in Biomolecules (Basel, Switzerland) (30-12-2019)“…is traditionally used in diabetes treatment in many Arabian countries; however, scientific evidence is lacking. Hence, the present study explored the…”
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One Pot Synthesis, Biological Efficacy of AuNPs and Au-Amoxicillin Conjugates Functionalized with Crude Flavonoids Extract of Micromeria biflora
Published in Molecules (Basel, Switzerland) (09-04-2023)“…Amoxicillin is the most widely used antibiotic in human medicine for treating bacterial infections. However, in the present research, extract mediated gold…”
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Response Surface Methodology (RSM)-Based Optimization of Ultrasound-Assisted Extraction of Sennoside A, Sennoside B, Aloe-Emodin, Emodin, and Chrysophanol from Senna alexandrina (Aerial Parts): HPLC-UV and Antioxidant Analysis
Published in Molecules (Basel, Switzerland) (04-01-2022)“…In this study, ultrasound-assisted extraction conditions were optimized to maximize the yields of sennoside A, sennoside B, aloe-emodin, emodin, and…”
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Posaconazole-hemp seed oil loaded nanomicelles for invasive fungal disease
Published in Scientific reports (18-07-2024)“…Invasive fungal infections (IFI) pose a significant health burden, leading to high morbidity, mortality, and treatment costs. This study aims to develop and…”
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Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles
Published in Materials (30-07-2023)“…Lung cancer is a formidable challenge in clinical practice owing to its metastatic nature and resistance to conventional treatments. The codelivery of…”
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Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line
Published in Molecules (Basel, Switzerland) (01-11-2019)“…is a medicinal plant that is widely used in Saudi folklore medicine for treatment of various diseases. fruit powder was sequentially extracted with -hexane,…”
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Evaluation of Cholinesterase Inhibitory Potential of Different Genotypes of Ziziphus nummularia , Their HPLC-UV, and Molecular Docking Analysis
Published in Molecules (Basel, Switzerland) (29-10-2020)“…is an important source of valuable phytoconstituents, which are widely used in traditional medicine system of Indo-Pak sub-continent. In this study we…”
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Palyno‐morphological investigations of halophytic taxa of Amaranthaceae through SEM from Salt range of Northern Punjab, Pakistan
Published in Microscopy research and technique (01-03-2019)“…The pollen morphology of 11 salt tolerant plant species of family Amaranthaceae from the salt range of Northern Punjab, Pakistan has been studied. The…”
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Assessment of the Anticancer Effect of Chlorojanerin Isolated from Centaurothamnus maximus on A549 Lung Cancer Cells
Published in Molecules (Basel, Switzerland) (29-03-2023)“…The goal of this study was to assess the anticancer efficacy of chlorojanerin against various cancer cells. The effects of chlorojanerin on cell cytotoxicity,…”
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Synthesis of some quinazolinones inspired from the natural alkaloid L-norephedrine as EGFR inhibitors and radiosensitizers
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2021)“…A set of quinazolinones synthesized by the aid of L-norephedrine was assembled to generate novel analogues as potential anticancer and radiosensitizing agents…”
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Cytotoxicity of Newly Synthesized Quinazoline-Sulfonamide Derivatives in Human Leukemia Cell Lines and Their Effect on Hematopoiesis in Zebrafish Embryos
Published in International journal of molecular sciences (25-04-2022)“…Many quinazoline derivatives with pharmacological properties, such as anticancer activity, have been synthesized. Fourteen quinazoline derivatives bearing a…”
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Obtaining New Candidate Peptides for Biological Anticancer Drugs from Enzymatic Hydrolysis of Human and Bovine Hemoglobin
Published in International journal of molecular sciences (01-10-2023)“…Enzymatic hydrolysis of bovine and human hemoglobin generates a diversity of bioactive peptides, mainly recognized for their antimicrobial properties. However,…”
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Janerin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis Involving the MAPK Pathway in THP-1, Leukemic Cell Line
Published in Molecules (Basel, Switzerland) (13-12-2021)“…Janerin is a cytotoxic sesquiterpene lactone that has been isolated and characterized from different species of the genus. In this study, janerin was isolated…”
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The Antiproliferative and Apoptotic Effects of a Novel Quinazoline Carrying Substituted-Sulfonamides: In Vitro and Molecular Docking Study
Published in Molecules (Basel, Switzerland) (01-02-2022)“…In order to investigate for a new effective and safe anticancer drug, we synthesized a novel series of quinazoline containing biologically active…”
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A Polyphenols-Rich Extract from Moricandia sinaica Boiss. Exhibits Analgesic, Anti-Inflammatory and Antipyretic Activities In Vivo
Published in Molecules (Basel, Switzerland) (30-10-2020)“…In this study, the aerial parts of were evaluated for their in vivo analgesic, anti-inflammatory and antipyretic activities. The analgesic activities were…”
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