Search Results - "Alpert, Michael H."
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Recovery from cold-induced reproductive dormancy is regulated by temperature-dependent AstC signaling
Published in Current biology (28-03-2022)“…Animals have evolved a variety of behaviors to cope with adverse environmental conditions. Similar to other insects, the fly, Drosophila melanogaster, responds…”
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2
A Circuit Encoding Absolute Cold Temperature in Drosophila
Published in Current biology (22-06-2020)“…Animals react to environmental changes over timescales ranging from seconds to days and weeks. An important question is how sensory stimuli are parsed into…”
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3
A descending dopamine pathway conserved from basal vertebrates to mammals
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2016)“…Dopamine neurons are classically known to modulate locomotion indirectly through ascending projections to the basal ganglia that project down to brainstem…”
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4
Rapid threat assessment in the Drosophila thermosensory system
Published in Nature communications (03-11-2023)“…Neurons that participate in sensory processing often display “ON” responses, i.e., fire transiently at the onset of a stimulus. ON transients are widespread,…”
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5
Robustness and plasticity in Drosophila heat avoidance
Published in Nature communications (06-04-2021)“…Simple innate behavior is often described as hard-wired and largely inflexible. Here, we show that the avoidance of hot temperature, a simple innate behavior,…”
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6
Forebrain dopamine neurons project down to a brainstem region controlling locomotion
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-2013)“…The contribution of dopamine (DA) to locomotor control is traditionally attributed to ascending dopaminergic projections from the substantia nigra pars…”
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7
Synaptic NMDA receptor-dependent Ca²⁺ entry drives membrane potential and Ca²⁺ oscillations in spinal ventral horn neurons
Published in PloS one (30-04-2013)“…During vertebrate locomotion, spinal neurons act as oscillators when initiated by glutamate release from descending systems. Activation of NMDA receptors…”
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8
Sensory biology: The bitter aftertaste
Published in Current biology (20-12-2021)“…Bitter taste signals a potentially toxic food that should be avoided. A new study shows that taste neurons in Drosophila produce distinct responses after a…”
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9
A thermometer circuit for hot temperature adjusts Drosophila behavior to persistent heat
Published in Current biology (26-09-2022)“…Small poikilotherms such as the fruit fly Drosophila depend on absolute temperature measurements to identify external conditions that are above (hot) or below…”
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10
Dynamic labelling of neural connections in multiple colours by trans-synaptic fluorescence complementation
Published in Nature communications (04-12-2015)“…Determining the pattern of activity of individual connections within a neural circuit could provide insights into the computational processes that underlie…”
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11
Descending Dopaminergic Inputs to Reticulospinal Neurons Promote Locomotor Movements
Published in The Journal of neuroscience (28-10-2020)“…Meso-diencephalic dopaminergic neurons are known to modulate locomotor behaviors through their ascending projections to the basal ganglia, which in turn…”
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12
Differential regulation of synaptic transmission by pre- and postsynaptic SK channels in the spinal locomotor network
Published in Journal of neurophysiology (01-06-2013)“…The generation of activity in the central nervous system requires precise tuning of cellular properties and synaptic transmission. Neural networks in the…”
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13
A synaptic mechanism for network synchrony
Published in Frontiers in cellular neuroscience (18-09-2014)“…Within neural networks, synchronization of activity is dependent upon the synaptic connectivity of embedded microcircuits and the intrinsic membrane properties…”
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14
Nitric oxide modulation of the electrically excitable skin of Xenopus laevis frog tadpoles
Published in Journal of experimental biology (01-11-2007)“…Nitric oxide (NO) is a highly diffusible signalling molecule with widespread effects on the integrative electrical properties of a variety of neuronal and…”
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15
Calcium-dependent Dendritic Signaling Properties in Lamprey Spinal Neurons During Locomotion
Published 01-01-2012“…A study was carried out to examine the electrical properties of spinal ventral horn neurons of the lamprey. These neurons generate rhythmic electrical activity…”
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