Search Results - "Alpert, Eric J."

Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia by Laukkanen, Saara, Veloso, Alexandra, Yan, Chuan, Oksa, Laura, Alpert, Eric J., Do, Daniel, Hyvärinen, Noora, McCarthy, Karin, Adhikari, Abhinav, Yang, Qiqi, Iyer, Sowmya, Garcia, Sara P., Pello, Annukka, Ruokoranta, Tanja, Moisio, Sanni, Adhikari, Sadiksha, Yoder, Jeffrey A., Gallagher, Kayleigh, Whelton, Lauren, Allen, James R., Jin, Alex H., Loontiens, Siebe, Heinäniemi, Merja, Kelliher, Michelle, Heckman, Caroline A., Lohi, Olli, Langenau, David M.

“…•Temsirolimus mTORC1 inhibitor and dasatinib kinase inhibitor synergize to kill a large fraction of xenograft and primary human T-ALL.•The LCK kinase, which is…”
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Single-cell imaging of T cell immunotherapy responses in vivo by Yan, Chuan, Yang, Qiqi, Zhang, Songfa, Millar, David G, Alpert, Eric J, Do, Daniel, Veloso, Alexandra, Brunson, Dalton C, Drapkin, Benjamin J, Stanzione, Marcello, Scarfò, Irene, Moore, John C, Iyer, Sowmya, Qin, Qian, Wei, Yun, McCarthy, Karin M, Rawls, John F, Dyson, Nick J, Cobbold, Mark, Maus, Marcela V, Langenau, David M

“…T cell immunotherapies have revolutionized treatment for a subset of cancers. Yet, a major hurdle has been the lack of facile and predicative preclinical…”
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