Search Results - "Alpar, D"

Evolutionary trajectories of hyperdiploid ALL in monozygotic twins by Bateman, C M, Alpar, D, Ford, A M, Colman, S M, Wren, D, Morgan, M, Kearney, L, Greaves, M

“…Identical twins have provided unique insights on timing or sequence of genetic events in acute lymphoblastic leukaemia (ALL). To date, this has mainly focused…”
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Clonal origins of ETV6-RUNX1+ acute lymphoblastic leukemia: studies in monozygotic twins by Alpar, D, Wren, D, Ermini, L, Mansur, M B, van Delft, F W, Bateman, C M, Titley, I, Kearney, L, Szczepanski, T, Gonzalez, D, Ford, A M, Potter, N E, Greaves, M

“…Studies on twins with concordant acute lymphoblastic leukemia (ALL) have revealed that ETV6-RUNX1 gene fusion is a common, prenatal genetic event with other…”
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Conserved hierarchical gain of chromosome 4 is an independent prognostic factor in high hyperdiploid pediatric acute lymphoblastic leukemia by Vojcek, Á, Pajor, G, Alpár, D, Mátics, R, Pótó, L, Szuhai, K, Pajor, L

“…Highlights • 8 chromosomes defined modal number by iFISH can prognostically stratify B-pALL. • Modal number of ≥ 55 relates significantly to better outcome of…”
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Tumor mutational burden and immune infiltrates in renal cell carcinoma and matched brain metastases by Steindl, A., Alpar, D., Heller, G., Mair, M.J., Gatterbauer, B., Dieckmann, K., Widhalm, G., Hainfellner, J.A., Schmidinger, M., Bock, C., Müllauer, L., Preusser, M., Berghoff, A.S.

“…Tumor mutational burden (TMB) and density of tumor-infiltrating lymphocytes (TIL) have been postulated as predictive biomarkers for immunotherapy. Therefore,…”
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Solution of a nonlinear heat transfer problem based on experimental data by Rysbaiuly, B., Alpar, S. D.

“…The paper develops a method for solving nonlinear equations of heat conduction. Two-layer container complexes have been created, the side faces of which are…”
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871 The Use of Automated Image-cytometry for Improved Non-invasive Bladder Cancer Detection by Multiprobe FISH Assay by Pajor, G, Alpar, D, Knief, B, Sule, N, Kajtar, B, Pajor, L, Somogyi, L, Melegh, B

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878 Novel Eight-target FISH Approach for Profiling Clonality of High-hyperdiploid Paediatric Acute Lymphoblastic Leukemia (HHD-pALL) by Pajor, G, Alpar, D, Szuhai, K, Knief, M, Poto, L, Vojcek, A, Ottoffy, G, Pajor, L

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Dissection of subclonal evolution by temporal mutation profiling in chronic lymphocytic leukemia patients treated with ibrutinib by Gángó, Ambrus, Alpár, Donát, Galik, Bence, Marosvári, Dóra, Kiss, Richárd, Fésüs, Viktória, Aczél, Dóra, Eyüpoglu, Ediz, Nagy, Noémi, Nagy, Ákos, Krizsán, Szilvia, Reiniger, Lilla, Farkas, Péter, Kozma, András, Ádám, Emma, Tasnády, Szabolcs, Réti, Marienn, Matolcsy, András, Gyenesei, Attila, Mátrai, Zoltán, Bödör, Csaba

“…The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib is inducing durable responses in chronic lymphocytic leukemia (CLL) patients with refractory/relapsed…”
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Stable preservation of SARS-COV-2 RNA from gargle samples on FTA cards by Kriegshäuser, G., Berndt, A., Alpar, D., Oberkanins, C.

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Molecular Subtypes and Genomic Profile of Primary Central Nervous System Lymphoma by Bödör, Csaba, Alpár, Donát, Marosvári, Dóra, Galik, Bence, Rajnai, Hajnalka, Bátai, Bence, Nagy, Ákos, Kajtár, Béla, Burján, Adrienn, Deák, Beáta, Schneider, Tamás, Alizadeh, Hussain, Matolcsy, András, Brandner, Sebastian, Storhoff, James, Chen, Ning, Liu, Mingdong, Ghali, Nadeem, Csala, Irén, Bagó, Attila G, Gyenesei, Attila, Reiniger, Lilla

“…Abstract Primary central nervous system lymphomas (PCNSL) are aggressive non-Hodgkin lymphomas affecting the central nervous system (CNS). Although…”
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W101 Stable preservation of SARS-COV-2 RNA from gargle samples on FTA cards by Kriegshäuser, G., Berndt, A., Alpar, D., Oberkanins, C.

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126 (PB114): A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer by Jung, P., Glaser, S.P., Han, J., Popa, A., Pisarsky, L., Feng, N., Geyer, A., Haderk, F., Alpar, D., Bristow, C., Drobits-Handl, B., Kasturirangan, S., Trapani, F., Marszalek, J.R., Tontsch-Grunt, U., Pearson, M., Heffernan, T.P., Kraut, N., Vellano, C.P., García-Martínez, J.M.

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P308: NOVEL COPY NUMBER ABERRATION‐BASED CLASSIFICATION METHODS REFINE RISK ASSESSMENT IN PEDIATRIC B‐CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA by Bedics, G., Egyed, B., Kotmayer, L., Benard‐Slagter, A., Groot, K., Bekő, A., Hegyi, L. L., Krizsán, S., Kriván, G., Erdélyi, D. J., Kovács, G., Kajtár, B., Pajor, L., Vojcek, Á., Ottóffy, G., Ujfalusi, A., Kiss, C., Szegedi, I., Bartyik, K., Péter, G., Sebestyén, E., Jakab, Z., Matolcsy, A., Savola, S., Bödör, C., Alpár, D.

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P615: BCL2 RESISTANCE MUTATIONS IN A REAL‐WORLD COHORT OF PATIENTS WITH VENETOCLAX‐TREATED CHRONIC LYMPHOCYTIC LEUKAEMIA by Kotmayer, L., László, T., Kiss, R., Hegyi, L. L., Mikala, G., Farkas, P., Balogh, A., Masszi, T., Demeter, J., Weisinger, J., Alizadeh, H., Gergely, L., Sulák, A., Egyed, M., Plander, M., Pettendi, P., Lévai, D., Schneider, T., Pauker, Z., Masszi, A., Szász, R., Bödör, C., Alpár, D.

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Tumour mutational burden and immune infiltrates in primary renal cell carcinoma and matched brain metastases by Steindl, A., Bergen, E.S., Alpar, D., Gatterbauer, B., Dieckmann, K., Widhalm, G., Hainfellner, J.A., Schmidinger, M., Bock, C., Müllauer, L., Preusser, M., Berghoff, A.S.

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403PD - Tumour mutational burden and immune infiltrates in primary renal cell carcinoma and matched brain metastases by Steindl, A., Bergen, E.S., Alpar, D., Gatterbauer, B., Dieckmann, K., Widhalm, G., Hainfellner, J.A., Schmidinger, M., Bock, C., Müllauer, L., Preusser, M., Berghoff, A.S.

“…High tumor mutational burden (TMB) as well as high density of tumor infiltrating lymphocytes (TIL) have been postulated as predictive response biomarkers for…”
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403PDTumour mutational burden and immune infiltrates in primary renal cell carcinoma and matched brain metastases by Steindl, A, Bergen, E S, Alpar, D, Gatterbauer, B, Dieckmann, K, Widhalm, G, Hainfellner, J A, Schmidinger, M, Bock, C, Müllauer, L, Preusser, M, Berghoff, A S

“…Abstract Background High tumor mutational burden (TMB) as well as high density of tumor infiltrating lymphocytes (TIL) have been postulated as predictive…”
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Parallel testing of liquid biopsy (ctDNA) and tissue biopsy samples reveals a higher frequency of EZH2 mutations in follicular lymphoma by Nagy, Ákos, Bátai, Bence, Kiss, Laura, Gróf, Stefánia, Király, Péter Attila, Jóna, Ádám, Demeter, Judit, Sánta, Hermina, Bátai, Árpád, Pettendi, Piroska, Szendrei, Tamás, Plander, Márk, Körösmezey, Gábor, Alizadeh, Hussain, Kajtár, Béla, Méhes, Gábor, Krenács, László, Timár, Botond, Csomor, Judit, Tóth, Erika, Schneider, Tamás, Mikala, Gábor, Matolcsy, András, Alpár, Donát, Masszi, András, Bödör, Csaba

“…Background Recent genomic studies revealed enhancer of zeste homolog 2 (EZH2) gain‐of‐function mutations, representing novel therapeutic targets in follicular…”
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Comprehensive profiling of disease-relevant copy number aberrations for advanced clinical diagnostics of pediatric acute lymphoblastic leukemia by Kiss, Richárd, Gángó, Ambrus, Benard-Slagter, Anne, Egyed, Bálint, Haltrich, Irén, Hegyi, Lajos, de Groot, Karel, Király, Péter Attila, Krizsán, Szilvia, Kajtár, Béla, Pikó, Henriett, Pajor, László, Vojcek, Ágnes, Matolcsy, András, Kovács, Gábor, Szuhai, Károly, Savola, Suvi, Bödör, Csaba, Alpár, Donát

“…Acute lymphoblastic leukemia is the most common pediatric cancer characterized by a heterogeneous genomic landscape with copy number aberrations occurring at…”
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Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax by Gángó, Ambrus, Kiss, Richárd, Farkas, Péter, Hanna, Eid, Demeter, Judit, Deák, Beáta, Lévai, Dóra, Kotmayer, Lili, Alpár, Donát, Matolcsy, András, Bödör, Csaba, Mátrai, Zoltán, Timár, Botond

“…Richter syndrome (RS) represents the development of high-grade lymphoma in patients with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma…”
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