Search Results - "Alotaibi, Ohoud J"

Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights by Sabt, Ahmed, Eldehna, Wagdy M., Al-Warhi, Tarfah, Alotaibi, Ohoud J., Elaasser, Mahmoud M., Suliman, Howayda, Abdel-Aziz, Hatem A.

“…Human health in the current medical era is facing numerous challenges, especially cancer. So, the therapeutic arsenal for cancer should be unremittingly…”
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Identification of Novel Cyanopyridones and Pyrido[2,3-d]Pyrimidines as Anticancer Agents with Dual VEGFR-2/HER-2 Inhibitory Action: Synthesis, Biological Evaluation and Molecular Docking Studies by Al-Warhi, Tarfah, Sallam, Al-Aliaa M, Hemeda, Loah R, El Hassab, Mahmoud A, Aljaeed, Nada, Alotaibi, Ohoud J, Doghish, Ahmed S, Noshy, Mina, Eldehna, Wagdy M, Ibrahim, Mona H

“…In the current work, we designed and synthesized three families of non-fused and fused compounds based on cyanopyridone: derivatives of…”
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Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII by Al-Warhi, Tarfah, Elbadawi, Mostafa M., Bonardi, Alessandro, Nocentini, Alessio, Al-Karmalawy, Ahmed A., Aljaeed, Nada, Alotaibi, Ohoud J., Abdel-Aziz, Hatem A., Supuran, Claudiu T., Eldehna, Wagdy M.

“…In this work, different series of benzothiazole-based sulphonamides 8a-c, 10, 12, 16a-b and carboxylic acids 14a-c were developed as novel SLC-0111 analogues…”
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Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies by Al-Warhi, Tarfah, Abo-Ashour, Mahmoud F., Almahli, Hadia, Alotaibi, Ohoud J., Al-Sanea, Mohammad M., Al-Ansary, Ghada H., Ahmed, Hanaa Y., Elaasser, Mahmoud M., Eldehna, Wagdy M., Abdel-Aziz, Hatem A.

“…As a continuation for our previous work, a novel set of N-alkylindole-isatin conjugates (7, 8a-c, 9 and 10a-e) is here designed and synthesised with the prime…”
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Discovery of 2,4-thiazolidinedione-tethered coumarins as novel selective inhibitors for carbonic anhydrase IX and XII isoforms by Eldehna, Wagdy M., Taghour, Mohammed S., Al-Warhi, Tarfah, Nocentini, Alessio, Elbadawi, Mostafa M., Mahdy, Hazem A., Abdelrahman, Mohamed A., Alotaibi, Ohoud J., Aljaeed, Nada, Elimam, Diaaeldin M., Afarinkia, Kamyar, Abdel-Aziz, Hatem A., Supuran, Claudiu T.

“…Different 2,4-thiazolidinedione-tethered coumarins 5a-b, 10a-n and 11a-d were synthesised and evaluated for their inhibitory action against the…”
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1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights by Al-Warhi, Tarfah, Almahli, Hadia, Maklad, Raed M, Elsayed, Zainab M, El Hassab, Mahmoud A, Alotaibi, Ohoud J, Aljaeed, Nada, Ayyad, Rezk R, Ghabour, Hazem A, Eldehna, Wagdy M, El-Ashrey, Mohamed K

“…Human health is experiencing several obstacles in the modern medical era, particularly cancer. As a result, the cancer therapeutic arsenal should be…”
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Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling by Al-Sanea, Mohammad M, Abelyan, Narek, Abdelgawad, Mohamed A, Musa, Arafa, Ghoneim, Mohammed M, Al-Warhi, Tarfah, Aljaeed, Nada, Alotaibi, Ohoud J, Alnusaire, Taghreed S, Abdelwahab, Sayed F, Helmy, Aya, Abdelmohsen, Usama Ramadan, Youssif, Khayrya A

“…SARS-CoV-2 (COVID-19), a novel coronavirus causing life-threatening pneumonia, caused a pandemic starting in 2019 and caused unprecedented economic and health…”
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New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation by Abdelgawad, Mohamed A., Al-Sanea, Mohammad M., Zaki, Mohamed A., Mohamed, Enas I. A., Khan, Shabana I., Tekwani, Babu L., Chittiboyina, Amar G, Khan, Ikhlas A, Al-Warhi, Tarfah, Aljaeed, Nada, Alotaibi, Ohoud J., Alkhaldi, Abdulsalam A. M., Elshemy, Heba A. H.

“…Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial…”
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Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer by Eldehna, Wagdy M, Nocentini, Alessio, Elsayed, Zainab M, Al-Warhi, Tarfah, Aljaeed, Nada, Alotaibi, Ohoud J, Al-Sanea, Mohammad M, Abdel-Aziz, Hatem A, Supuran, Claudiu T

“…Pursuing our effort for developing effective inhibitors of the cancer-related hCA IX isoform, here we describe the synthesis of novel benzofuran-based…”
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