Search Results - "Alonso Montes"
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Fibrosis in Chronic Kidney Disease: Pathogenesis and Consequences
Published in International journal of molecular sciences (02-01-2021)“…Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix as a response to different types of tissue injuries, which leads…”
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Chronic Kidney Disease—Mineral and Bone Disorders: Pathogenesis and Management
Published in Calcified tissue international (01-04-2021)“…The key players of the chronic kidney disease-mineral and bone disorders (CKD-MBD) are calcium, phosphate, PTH, FGF23, and the vitamin D hormonal system. The…”
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Direct inhibition of osteoblastic Wnt pathway by fibroblast growth factor 23 contributes to bone loss in chronic kidney disease
Published in Kidney international (01-07-2016)“…Bone loss and increased fractures are common complications in chronic kidney disease. Because Wnt pathway activation is essential for normal bone…”
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Variants in cardiac GATA genes associated with bicuspid aortic valve
Published in European journal of clinical investigation (01-12-2018)“…Background Bicuspid aortic valve (BAV) is a heterogeneous and still not fully understood condition, with diverse genetic aetiology and associated phenotypes…”
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5
Experimental Models to Study Diabetes Mellitus and Its Complications: Limitations and New Opportunities
Published in International journal of molecular sciences (01-06-2023)“…Preclinical biomedical models are a fundamental tool to improve the knowledge and management of diseases, particularly in diabetes mellitus (DM) since,…”
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RANKL, but Not R-Spondins, Is Involved in Vascular Smooth Muscle Cell Calcification through LGR4 Interaction
Published in International journal of molecular sciences (01-06-2024)“…Vascular calcification has a global health impact that is closely linked to bone loss. The Receptor Activator of Nuclear Factor Kappa B (RANK)/RANK ligand…”
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Role of Klotho and AGE/RAGE-Wnt/β-Catenin Signalling Pathway on the Development of Cardiac and Renal Fibrosis in Diabetes
Published in International journal of molecular sciences (01-03-2023)“…Fibrosis plays an important role in the pathogenesis of long-term diabetic complications and contributes to the development of cardiac and renal dysfunction…”
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Soluble Klotho, a Potential Biomarker of Chronic Kidney Disease-Mineral Bone Disorders Involved in Healthy Ageing: Lights and Shadows
Published in International journal of molecular sciences (01-02-2024)“…Shortly after the discovery of Klotho, interest grew in its potential role in chronic kidney disease (CKD). There are three isoforms of the Klotho protein:…”
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Novel Biomarkers of Bone Metabolism
Published in Nutrients (22-02-2024)“…Bone represents a metabolically active tissue subject to continuous remodeling orchestrated by the dynamic interplay between osteoblasts and osteoclasts. These…”
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Serum and Urinary Soluble α-Klotho as Markers of Kidney and Vascular Impairment
Published in Nutrients (01-03-2023)“…This study was designed to investigate the controversy on the potential role of sKlotho as an early biomarker in Chronic Kidney Disease-Mineral Bone Disorder…”
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Phosphorus May Induce Phenotypic Transdifferentiation of Vascular Smooth Muscle Cells through the Reduction of microRNA-145
Published in Nutrients (27-06-2023)“…Phosphorus is a vital element for life found in most foods as a natural component, but it is also one of the most used preservatives added during food…”
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Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure
Published in Nutrients (01-04-2023)“…Drugs providing antihypertensive and protective cardiovascular actions are of clinical interest in controlling cardiovascular events and slowing the…”
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13
Group-Level Progressive Alterations in Brain Connectivity Patterns Revealed by Diffusion-Tensor Brain Networks across Severity Stages in Alzheimer's Disease
Published in Frontiers in aging neuroscience (07-07-2017)“…Alzheimer's disease (AD) is a chronically progressive neurodegenerative disease highly correlated to aging. Whether AD originates by targeting a localized…”
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Redox Metabolism and Vascular Calcification in Chronic Kidney Disease
Published in Biomolecules (Basel, Switzerland) (01-09-2023)“…Vascular calcification (VC) is a common complication in patients with chronic kidney disease which increases their mortality. Although oxidative stress is…”
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15
Fast retinal vessel tree extraction: A pixel parallel approach
Published in International journal of circuit theory and applications (01-07-2008)“…Early ocular disease diagnosis is an important field in medical research. From the image processing point of view, many strategies and algorithms have been…”
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Retinoids during the in vitro transition from bovine morula to blastocyst
Published in Human reproduction (Oxford) (01-08-2006)“…The conversion of retinol (ROH) to retinoic acid (RA) is crucial during development but has been not studied during blastocyst formation. METHODS AND RESULTS:…”
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Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease
Published in Journal of Alzheimer's disease (01-04-2008)“…Impaired mitochondrial function and an increased number of mutations in mitochondrial DNA (mtDNA) has been found in brains of patients with late-onset…”
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Oocytes recovered from cows treated with retinol become unviable as blastocysts produced in vitro
Published in Reproduction (Cambridge, England) (01-04-2005)“…Retinoids have been shown to enhance developmental competence of the oocyte in cattle, sheep and pigs. In this study we investigated whether exogenous retinol…”
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Screening of the endothelin1 gene (EDN1) in a cohort of patients with essential left ventricular hypertrophy
Published in Annals of human genetics (01-09-2007)“…Summary Our objective was to analyse the role of endothelin1 gene (EDN1) variation in essential left ventricular hypertrophy (LVH). We searched for EDN1…”
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Knowledge, Attitudes and Practice Regarding Antibiotic Prescription by Medical Interns: A Qualitative Study in Spain
Published in Antibiotics (Basel) (24-02-2023)“…Antibiotic resistance is an issue of growing importance in the public health sphere. Medical interns are of great relevance when it comes to the source of this…”
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