Search Results - "Alonso, M.J."
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Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials
Published in Advanced drug delivery reviews (15-11-2016)“…The development of oral dosage forms that allows absorption of therapeutic peptides to the systemic circulation is one of the greatest challenges for the…”
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Nanotherapies for the treatment of ocular diseases
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2015)“…[Display omitted] •Nanosystems can interact with the ocular mucosa upon topical administration.•Improved interactions translate into improved therapeutic…”
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Vaccine delivery carriers: Insights and future perspectives
Published in International journal of pharmaceutics (02-01-2013)“…Vaccination is undoubtedly the most effective health intervention for disease prevention and eradication. Nevertheless, currently there is still a need for…”
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Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction
Published in International journal of pharmaceutics (31-10-2006)“…In this work the production of auto-assembled nanoparticles obtained by the mixing of chitosan and lecithin is presented. The size and surface charge of the…”
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Association between maltreatment and polydrug use among adolescents
Published in Child abuse & neglect (01-01-2016)“…Abstract Different studies have related sexual and physical abuse during childhood and adolescence to the development of substance abuse disorders…”
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P037 Transcranial static magnetic field stimulation-induced modulation of motor cortex excitability in Parkinson’s disease
Published in Clinical neurophysiology (01-03-2017)“…Question tSMS is a new non-pharmacological, low-cost, non-invasive brain stimulation (NIBS) technique that decreases cortical excitability in healthy subjects…”
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Poly(lactic acid)-poly(ethylene glycol) nanoparticles as new carriers for the delivery of plasmid DNA
Published in Journal of controlled release (10-07-2001)“…The purpose of the present work was to produce and characterize poly(lactic acid)-poly(ethylene glycol) (PLA-PEG) nanoparticles (size lower than 300 nm)…”
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The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration
Published in Colloids and surfaces, B, Biointerfaces (01-10-2000)“…The aim of the present work was to evaluate if the presence of a polyethylenglycol (PEG) coating around PLA nanoparticles would affect their interaction with…”
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502 MI130004, an antibody–drug conjugate including a novel payload of marine origin: Evidences of in vivo activity
Published in European journal of cancer (1990) (01-11-2014)Get full text
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Transcranial static magnetic field stimulation modulates motor cortex excitability in off medication PD patients
Published in Brain stimulation (01-03-2017)Get full text
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Design of microencapsulated chitosan microspheres for colonic drug delivery
Published in Journal of controlled release (02-03-1998)“…Among the different approaches to achieve colon-selective drug delivery, the use of polymers, specifically biodegraded by colonic bacteria, holds great…”
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Development and characterization of protein-loaded poly(lactide-co-glycolide) nanospheres
Published in European journal of pharmaceutics and biopharmaceutics (01-06-1997)“…The goal of this work is to develop poly(lactide-co-glycolide) (PLGA) nanospheres designed to deliver proteins for extended periods of time. To accomplish this…”
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669 P21WAF1 Represses Cell Cycle Genes in K562 Cells Acting as a Transcriptional Modulator
Published in European journal of cancer (1990) (01-07-2012)Get full text
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Seasonal variation in chemical constituents of Santolina rosmarinifolia L. ssp. rosmarinifolia
Published in Biochemical systematics and ecology (01-07-2001)“…The seasonal variation of the essential oil extracts from the aerial parts of a Santolina rosmarinifolia population has been studied. Oil yields increased in…”
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Analysis by gas chromatography–mass spectrometry of the essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species to the Canary Islands, Spain
Published in Journal of Chromatography A (18-11-2005)“…The essential oils from the aerial parts of Pimpinella anagodendron Bolle and Pimpinella rupicola Svent., two endemic species growing in Tenerife, Canary…”
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Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma
Published in International journal of pharmaceutics (03-11-2009)“…The purpose of this study was to produce mucoadhesive nanocarriers made from chitosan (CS) and hyaluronic acid (HA), and containing the macromolecular drug…”
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Evaluation of prenatal contingent screening for chromosomal alterations
Published in Clinica chimica acta (01-06-2019)Get full text
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Polysaccharide colloidal particles as delivery systems for macromolecules
Published in Advanced drug delivery reviews (23-03-2001)“…Mucosal delivery of complex molecules such as peptides, proteins, oligonucleotides, and plasmids is one of the most intensively studied subjects. The use of…”
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Glucomannan, a promising polysaccharide for biopharmaceutical purposes
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2009)“…Over the last few decades, polysaccharides have gained increasing attention in the biomedical and drug delivery fields. Among them, glucomannan (GM), has…”
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