Search Results - "Alonso, Lais"

Photoinactivation of Salmonella enterica (serovar Typhimurium) by tetra-cationic porphyrins containing peripheral [Ru(bpy)2Cl]+ units by Gonçalves, Pablo J., Bezzerra, Fabio C., Teles, Amanda V., Menezes, Lucas B., Alves, Kamilla M., Alonso, Lais, Alonso, Antonio, Andrade, Maria A., Borissevitch, Iouri E., Souza, Guilherme R.L., Iglesias, Bernardo A.

“…[Display omitted] •Cationic tetra-ruthenaed porphyrins were used to photoinactivation of Salmonella.•meso-tetra-ruthenaed(4-pyridyl)porphyrin free-base and its…”
Get full text

Proteomic alterations in Paracoccidioides brasiliensis caused by exposure to curcumin by Rocha, Olivia Basso, Freitas e Silva, Kleber Santiago, de Carvalho Junior, Marcos Antônio Batista, Moraes, Dayane, Alonso, Antônio, Alonso, Laís, do Carmo Silva, Lívia, Soares, Celia Maria Almeida, Pereira, Maristela

“…Paracoccidioides spp. are the etiological agent of paracoccidioidomycosis, a disease that causes skin lesions and affect the lungs and other organs. The…”
Get full text

Synthesis, Antileishmanial Activity and Spin Labeling EPR Studies of Novel β-Carboline-Oxazoline and β-Carboline-Dihydrooxazine Derivatives by Baréa, Paula, de Paula, Jéssica, Alonso, Laís, de Oliveira, Aline, da Costa, Willian, Alonso, Antonio, Nakamura, Celso, Sarragiotto, Maria

“…A series of novel 1-(substituted-phenyl)-3-(4,5-dihydro-1,3-oxazol-2-yl)-9H-β-carboline (8a-8i) and…”
Get full text

Synergistic antifungal interaction of N -(butylcarbamothioyl) benzamide and amphotericin B against Cryptococcus neoformans by Andriani, Gabriella Maria, Spoladori, Lais Fernanda de Almeida, Fabris, Marciéli, Camargo, Priscila Goes, Pereira, Patrícia Morais Lopes, Santos, Jussevania Pereira, Bartolomeu-Gonçalves, Guilherme, Alonso, Lais, Lancheros, Cesar Armando Contreras, Alonso, Antonio, Nakamura, Celso Vataru, Macedo, Jr, Fernando, Pinge-Filho, Phileno, Yamauchi, Lucy Megumi, Bispo, Marcelle de Lima Ferreira, Tavares, Eliandro Reis, Yamada-Ogatta, Sueli Fumie

“…is one of the leading causes of invasive fungal infections worldwide. Cryptococcal meningoencephalitis is the main challenge of antifungal therapy due to high…”
Get full text

Antiprotozoal Activity of Benzoylthiourea Derivatives against Trypanosoma cruzi: Insights into Mechanism of Action by Pereira, Patrícia Morais Lopes, Fernandes, Bruna Terci, dos Santos, Vitória Ribeiro, Cabral, Weslei Roberto Correia, Lovo-Martins, Maria Isabel, Alonso, Lais, Lancheros, César Armando Contreras, de Paula, Jéssica Carreira, Camargo, Priscila Goes, Suzukawa, Helena Tiemi, Alonso, Antônio, Macedo, Fernando, Nakamura, Celso Vataru, Tavares, Eliandro Reis, de Lima Ferreira Bispo, Marcelle, Yamauchi, Lucy Megumi, Pinge-Filho, Phileno, Yamada-Ogatta, Sueli Fumie

“…For decades, only two nitroheterocyclic drugs have been used as therapeutic agents for Chagas disease. However, these drugs present limited effectiveness…”
Get full text

Hemolytic potential of miltefosine is dependent on cell concentration: Implications for in vitro cell cytotoxicity assays and pharmacokinetic data by Alonso, Lais, Alonso, Antonio

“…Miltefosine possesses antiparasitic, antibacterial, antifungal and antitumor activities; however, its mechanism of action is not well established. In the…”
Get full text

Antileishmanial activity of 3,4,5-trisubstituted isoxazoles by interaction with Leishmania amazonensis plasma membrane by Alonso, Lais, Pianoski, Karlos Eduardo, Alonso, Antonio, Rosa, Fernanda Andreia

“…•Neglected Tropical diseases have developed into a serious public health problem.•Negligence in the treatment contributes to high morbidity and mortality…”
Get full text

Plasma membrane rigidity effects of 4-hydroxy-2-nonenal in Leishmania, erythrocyte and macrophage by Alonso, Lais, Menegatti, Ricardo, Dorta, Miriam Leandro, Alonso, Antonio

“…4-hydroxy-2-nonenal (HNE) is a reactive aldehyde produced by cells under conditions of oxidative stress, which has been shown to react with proteins and…”
Get full text

Analysis of the Interactions of Amphotericin B with the Leishmania Plasma Membrane Using EPR Spectroscopy by Alonso, Lais, Mendanha, Sebastião Antônio, Dorta, Miriam Leandro, Alonso, Antonio

“…Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the interactions of amphotericin B (AmB) with the plasma membrane of…”
Get full text

Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol by Alonso, Lais, Pimenta, Laryssa Ketelyn Lima, Kipnis, André, Alonso, Antonio

“…Spin label electron paramagnetic resonance (EPR) spectroscopy was used to characterize the components of the Mycobacterium abscessus massiliense cell envelope…”
Get more information

Comparative EPR spectroscopy analysis of amphotericin B and miltefosine interactions with Leishmania, erythrocyte and macrophage membranes by Alonso, Lais, Mendanha, Sebastião Antônio, Gomes, Rodrigo Saar, Dorta, Miriam Leandro, Alonso, Antonio

“…•Amphotericin B (AmB) reduced the membrane probe dynamics in Leishmania parasite.•AmB membrane concentration was assessed in terms of its antiproliferative…”
Get full text

Combination of lipid nanoparticles and iontophoresis for enhanced lopinavir skin permeation: Impact of electric current on lipid dynamics by Moura, Rayssa Barbary Pedroza, Andrade, Lígia Marquez, Alonso, Lais, Alonso, Antonio, Marreto, Ricardo Neves, Taveira, Stephânia Fleury

“…Nanostructured lipid carriers (NLC)-loaded with lopinavir (LPV) were developed for its iontophoretic transdermal delivery. Electronic paramagnetic resonance…”
Get full text

Interactions of miltefosine with erythrocyte membrane proteins compared to those of ionic surfactants by Alonso, Lais, Cardoso, Éder Jéferson Souza, Mendanha, Sebastião Antônio, Alonso, Antonio

“…[Display omitted] •The zwitterionic compounds miltefosine and HPS showed similar results in this study.•SDS was the least effective compound for increasing…”
Get full text

Antileishmanial activity of the chalcone derivative LQFM064 associated with reduced fluidity in the parasite membrane as assessed by EPR spectroscopy by Alonso, Lais, Menegatti, Ricardo, Gomes, Rodrigo Saar, Dorta, Miriam Leandro, Luzin, Rangel Magalhães, Lião, Luciano Morais, Alonso, Antonio

“…•LQFM064 causes cell membrane rigidity, as detected by EPR spectroscopy.•EPR spectroscopy suggests that LQFM064 causes peroxidation of membrane…”
Get full text

In vitro antileishmanial and cytotoxic activities of nerolidol are associated with changes in plasma membrane dynamics by Alonso, Lais, Fernandes, Kelly Souza, Mendanha, Sebastião Antônio, Gonçalves, Pablo José, Gomes, Rodrigo Saar, Dorta, Miriam Leandro, Alonso, Antonio

“…The sesquiterpene nerolidol is a membrane-active compound that has demonstrated antitumor, antibacterial, antifungal and antiparasitic activities. In this…”
Get full text

Membrane dynamics in Leishmania amazonensis and antileishmanial activities of β-carboline derivatives by Alonso, Lais, de Paula, Jéssica Carreira, Baréa, Paula, Sarragiotto, Maria Helena, Ueda-Nakamura, Tânia, Alonso, Antonio, de Souza Fernandes, Nilma, Lancheros, César Armando Contreras, Volpato, Hélito, Lazarin-Bidóia, Danielle, Nakamura, Celso Vataru

“…Two β-carboline compounds, 8i and 6d, demonstrated in vitro antileishmanial activity against Leishmania (L.) amazonensis promastigotes similar to that of…”
Get full text

Antileishmanial and cytotoxic activities of ionic surfactants compared to those of miltefosine by Alonso, Lais, Cardoso, Éder Jeferson Souza, Gomes, Rodrigo Saar, Mendanha, Sebastião Antônio, Dorta, Miriam Leandro, Alonso, Antonio

“…[Display omitted] •The IC50 of miltefosine on Leishmania was cell-concentration dependent.•Ionic surfactants increased the dynamics of the parasite membrane…”
Get full text

Miltefosine Increases Lipid and Protein Dynamics in Leishmania amazonensis Membranes at Concentrations Similar to Those Needed for Cytotoxicity Activity by ALVES MOREIRA, Rodrigo, MENDANHA, Sebastião Antonio, FERNANDES, Kelly Souza, GUIMARES MATOS, Grazzielle, ALONSO, Lais, DORTA, Miriam Leandro, ALONSO, Antonio

“…Miltefosine (MT) is a membrane-active alkylphospholipid licensed for the topical treatment of breast cancer skin metastases and the oral treatment of…”
Get full text

Antileishmanial activities of three chalcone derivatives and their association with plasma membrane rigidity as assessed by EPR spectroscopy by Borges, Ellyêssa Nascimento, Alonso, Lais, Silveira, Murilo Barros, Balbinot, Rodolfo Bento, Nakamura, Celso V., da Rocha, André Luis Batista, Arruda, Evilanna Lima, dos Santos, Gabriel Franco, Vaz, Boniek G., Gomides, Christian Dias, Lião, Luciano Morais, Menegatti, Ricardo, Alonso, Antonio

“…•LQFM332 causes cell membrane rigidity, as detected by EPR spectroscopy.•Membrane rigidity was associated with antileishmanial activity.•EPR spectra suggest…”
Get full text

Paracoccidioides brasiliensis plasma membrane characterization by EPR spectroscopy and interactions with amphotericin B, miltefosine and nerolidol by Alonso, Lais, Rocha, Olivia Basso, de Carvalho Junior, Marcos Antônio Batista, Soares, Célia Maria de Almeida, Pereira, Maristela, Alonso, Antonio

“…Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to characterize the interactions of amphotericin B (AmB), miltefosine (MIL) and…”
Get full text