Search Results - "Alomar, Fadhel A."
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Impact of SLCO1B15 on Flucloxacillin and Co-Amoxiclav–Related Liver Injury
Published in Frontiers in pharmacology (08-06-2022)“…Background: Idiosyncratic drug-induced liver injury (DILI) is a serious uncommon disease that may develop as a result of the intake of certain drugs such as…”
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Development of surface modified bilosomes for the oral delivery of quercetin: optimization, characterization in-vitro antioxidant, antimicrobial, and cytotoxicity study
Published in Drug delivery (01-12-2022)“…Quercetin (QT) is a flavonoid that exhibits anti-oxidant and chemo-preventive activity. This research work aimed to develop surface-modified bilosomes (BS) of…”
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HIV-Tat Exacerbates the Actions of Atazanavir, Efavirenz, and Ritonavir on Cardiac Ryanodine Receptor (RyR2)
Published in International journal of molecular sciences (23-12-2022)“…The incidence of sudden cardiac death (SCD) in people living with HIV infection (PLWH), especially those with inadequate viral suppression, is high and the…”
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Rosinidin Protects Streptozotocin-Induced Memory Impairment-Activated Neurotoxicity by Suppressing Oxidative Stress and Inflammatory Mediators in Rats
Published in Medicina (Kaunas, Lithuania) (26-07-2022)“…Background and Objectives: To assess the antioxidant and neuroprotective role of rosinidin on rat memory impairment that is induced by streptozotocin…”
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The prevalence of polypharmacy and hyper-polypharmacy among middle-aged vs . older patients in Saudi Arabia: a cross-sectional study
Published in Frontiers in pharmacology (12-06-2024)“…Polypharmacy, the use of multiple medications, is a growing concern among middle-aged and older patients, posing potential risks and challenges in healthcare…”
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Impact of telemedicine on glycemic control in type 2 diabetes mellitus during the COVID-19 lockdown period
Published in Frontiers in endocrinology (Lausanne) (03-02-2023)“…The lockdown at the start of coronavirus disease 2019 (COVID-19) pandemic in Saudi Arabia (March 2020 to June 2020) shifted routine in-person care for patients…”
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Elevated plasma level of the glycolysis byproduct methylglyoxal on admission is an independent biomarker of mortality in ICU COVID-19 patients
Published in Scientific reports (09-06-2022)“…Biomarkers to identify ICU COVID-19 patients at high risk for mortality are urgently needed for therapeutic care and management. Here we found plasma levels of…”
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Arabinoxylan-Carboxymethylcellulose Composite Films for Antibiotic Delivery to Infected Wounds
Published in Polymers (27-04-2022)“…Modern dressings should provide for local delivery of antibiotics and protect the wound from bacterial infection, dehydration and environmental factors to…”
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Anti-Huntington's Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
Published in Biomolecules (Basel, Switzerland) (23-07-2022)“…Rosiridin is a compound extracted from ; water extracts of root elicit positive effects on the human central nervous system and improve brain function. They…”
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Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats
Published in Antioxidants (06-07-2020)“…Accumulation of methylglyoxal (MG) arising from downregulation of its primary degrading enzyme glyoxalase-1 (Glo1) is an underlying cause of diabetic…”
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A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection
Published in Frontiers in cardiovascular medicine (14-12-2021)“…Early-onset heart failure (HF) continues to be a major cause of morbidity and mortality in people living with human immunodeficiency virus type one (HIV-1)…”
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Efavirenz, atazanavir, and ritonavir disrupt sarcoplasmic reticulum Ca2+ homeostasis in skeletal muscles
Published in Antiviral research (01-03-2021)“…While muscle fatigue, pain and weakness are common co-morbidities in HIV-1 infected people, their underlying cause remain poorly defined. To this end, we…”
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HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice
Published in Scientific reports (16-06-2020)“…The molecular cause(s) for early onset heart failure in people living with HIV-1 infection (PLWH) remains poorly defined. Herein, longitudinal echocardiography…”
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Pattern of Prescribing Proton Pump Inhibitors: Evaluating Appropriateness and Factors Contributing to Their Adverse Effect Reaction Risk
Published in Journal of clinical medicine (17-10-2024)“…: Proton pump inhibitors (PPIs) are amongst the most commonly prescribed classes of medication. However, inappropriate PPI use can lead to several adverse drug…”
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Elevated Vulnerability of Chronic Leukemia Patients to COVID-19 Infection: A Systems Biology Approach
Published in Dr. Sulaiman Al Habib medical journal (2022)“…Background Emerging evidence has shown that SARS-CoV-2 may affect the circulatory system in addition to the human respiratory system. However, no study has…”
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Europinidin Enhances Healing through Modulating Antioxidant Processes in Experimentally Induced-Stomach Ulcer Condition
Published in International journal of pharmacology (15-07-2022)Get full text
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Efavirenz, atazanavir, and ritonavir disrupt sarcoplasmic reticulum Ca 2+ homeostasis in skeletal muscles
Published in Antiviral research (01-03-2021)“…While muscle fatigue, pain and weakness are common co-morbidities in HIV-1 infected people, their underlying cause remain poorly defined. To this end, we…”
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