Search Results - "Aloke, Chinyere"
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Elemental Composition and Associated Health Risk of Honey Obtained from Apiary Farms in Southeast Nigeria
Published in Journal of food protection (01-10-2020)“…This study investigated the levels of lead, selenium, arsenic, iron, manganese, copper, zinc, chromium, cadmium, and nickel in honey and their potential health…”
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2
Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats
Published in Life sciences (1973) (15-10-2020)“…Cadmium is a persistent ubiquitous environmental toxicant that elicits several biological defects on delicate body organs. Growing evidence suggests that…”
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3
Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine
Published in Molecules (Basel, Switzerland) (31-05-2024)“…There is a myriad of diseases that plague the world ranging from infectious, cancer and other chronic diseases with varying interventions. However, the…”
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Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase
Published in The Protein Journal (01-02-2022)“…Patients in health-care settings develop nosocomial infections due to prolonged hospital stay. The Gram negative Klebsiella pneumoniae ( K. pneumoniae ), is a…”
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5
Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives
Published in Viruses (03-01-2023)“…Lassa fever (LF) is a rodent-borne disease that threatens human health in the sub-region of West Africa where the zoonotic host of Lassa virus (LASV) is…”
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Effect of acetogenin fraction of Annona muricata leaves on antioxidant status and some indices of benign prostatic hyperplasia in rats
Published in Redox report : communications in free radical research (01-01-2020)“…Objectives: This work investigated the effect of acetogenin-rich fraction of Annona muricata leaves (AFAL) on antioxidant status and some markers of benign…”
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Current Advances in the Management of Diabetes Mellitus
Published in Biomedicines (29-09-2022)“…Diabetes mellitus (DM) underscores a rising epidemic orchestrating critical socio-economic burden on countries globally. Different treatment options for the…”
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Engineering a Pseudo-26-kDa Schistosoma Glutathione Transferase from bovis / haematobium for Structure, Kinetics, and Ligandin Studies
Published in Biomolecules (Basel, Switzerland) (07-12-2021)“…Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with…”
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Effects of co-treatment of Plasmodium berghei-infected mice with aqueous extract of Ocimum gratissimum leaves and primaquine on glucose-6-phosphate dehydrogenase activity, hematological, and antioxidant parameters
Published in Journal of ayurveda and integrative medicine (01-10-2022)“…It has been observed that most malaria patients especially G6PD-deficient patients usually experience oxidative stress and severe anemia when treated with…”
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Medicinal plants: A promising source of anti-diabetic agents in sub-Sahara Africa
Published in Current issues in pharmacy and medical sciences (01-06-2023)“…The rising burden of Diabetes mellitus (DM) globally and particularly in sub-Sahara Africa calls for alternative treatment solutions. This is because the…”
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Assessment of the Antimalarial Treatment Failure in Ebonyi State, Southeast Nigeria
Published in Journal of xenobiotics (03-01-2023)“…The fight against malaria is a continuum as the epidemic is not abating. For proper deployment of tools in the fight against malaria, an assessment of the…”
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In Vivo and in Silico Assessment of Ameliorative Effects of Xylopia aethiopica on Testosterone Propionate-Induced Benign Prostatic Hyperplasia
Published in Pharmaceutical fronts (01-06-2023)“…Abstract Xylopia aethiopica (XAE) is a commonly used herbal medicine and contains rich active ingredients for a variety of biological activities. The study…”
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HPLC profiling and studies on Copaifera salikounda methanol leaf extract on phenylhydrazine-induced hematotoxicity and oxidative stress in rats
Published in Arabian journal of chemistry (01-12-2021)“…Anemia is a clinical disorder orchestrated by factors such as drugs, including phenylhydrazine (PHZ). This study explored the protective roles of Copaifera…”
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Antihyperglycemic, antihyperlipidemic and hepatoprotective effects of Ficus ottoniifolia (Miq.) Miq. supplementation in alloxan-induced diabetic rats
Published in Avicenna journal of phytomedicine (01-09-2021)“…Medicinal plants provide better and cheaper alternative therapy for management of several diseases compared to orthodox medicines. This study evaluated the…”
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Impact of Drug Pressure versus Limited Access to Drug in Malaria Control: The Dilemma
Published in Medicines (Basel, Switzerland) (04-01-2022)“…Malaria burden has severe impact on the world. Several arsenals, including the use of antimalarials, are in place to curb the malaria burden. However, the…”
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ANTI-DIABETIC EFFECT OF ETHANOL EXTRACT OF Copaifera salikounda (HECKEL) AGAINST ALLOXAN-INDUCED DIABETES IN RATS
Published in Slovenski veterinarski zbornik (01-01-2021)“…Accumulating evidences have reinforced the use of medicinal plants in the treatment of various ailments as a result of negative side effects associated with…”
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Coping with the ESKAPE pathogens: Evolving strategies, challenges and future prospects
Published in Microbial pathogenesis (01-02-2023)“…Globally, the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and…”
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Glutathione S-transferase: A versatile and dynamic enzyme
Published in Biochemical and biophysical research communications (19-11-2024)“…The dynamic and versatile group of enzymes referred to as glutathione S-transferases (GSTs) play diverse roles in cellular detoxification, safeguarding hosts…”
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Exploring NAD+ metabolism and NNAT: Insights from structure, function, and computational modeling
Published in Biochimie (01-05-2024)“…Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme, is ubiquitously distributed and serves crucial functions in diverse biological processes, encompassing…”
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Exploiting Copaifera salikounda compounds as treatment against diabetes: An insight into their potential targets from a computational perspective
Published in Computational biology and chemistry (01-06-2023)“…Accumulating evidence has shown that medicinal plants have been exploited for treatment purposes since time immemorial. Thus, this study investigated the…”
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