Search Results - "Alokail, Majed S"

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    Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (Riyadh cohort 2): a decade of an epidemic by Al-Daghri, Nasser M, Al-Attas, Omar S, Alokail, Majed S, Alkharfy, Khalid M, Yousef, Mansour, Sabico, Shaun Louie, Chrousos, George P

    Published in BMC medicine (20-06-2011)
    “…Follow-up epidemiologic studies are needed to assess trends and patterns of disease spread. No follow-up epidemiologic study has been done in the Kingdom of…”
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    Effect of Antihypertensive Drug (Chlorothiazide) on Fibrillation of Lysozyme: A Combined Spectroscopy, Microscopy, and Computational Study by Altwaijry, Nojood, Almutairi, Ghaliah S, Khan, Mohd Shahnawaz, Shaik, Gouse M, Alokail, Majed S

    “…Amyloid fibrils abnormally accumulate together in the human body under certain conditions, which can result in lethal conditions. Thus, blocking this…”
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    Anticancer Potential of Biogenic Silver Nanoparticles: A Mechanistic Study by Khan, Mohd Shahnawaz, Alomari, Alya, Tabrez, Shams, Hassan, Iftekhar, Wahab, Rizwan, Bhat, Sheraz Ahmad, Alafaleq, Nouf Omar, Altwaijry, Nojood, Shaik, Gouse M., Zaidi, Syed Kashif, Nouh, Wessam, Alokail, Majed S., Ismael, Mohamed A.

    Published in Pharmaceutics (12-05-2021)
    “…The continuous loss of human life due to the paucity of effective drugs against different forms of cancer demands a better/noble therapeutic approach. One…”
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    Agitation does not induce fibrillation in reduced hen egg‐white lysozyme at physiological temperature and pH by Malik, Ajamaluddin, Khan, Javed Masood, Alhomida, Abdullah S., Ola, Mohammad Shamsul, Alokail, Majed S., Khan, Mohd Shahnawaz, Alenad, Amal M., Altwaijry, Nojood, Alafaleq, Nouf Omar, Odeibat, Hamza

    Published in Journal of molecular recognition (01-06-2023)
    “…Several proteins and peptides tend to form an amyloid fibril, causing a range of unrelated diseases, from neurodegenerative to certain types of cancer. In the…”
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    Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients by Al-Daghri, Nasser M., Mohammed, Abdul Khader, Al-Attas, Omar S., Ansari, Mohammed Ghouse Ahmed, Wani, Kaiser, Hussain, Syed D., Sabico, Shaun, Tripathi, Gyanendra, Alokail, Majed S.

    Published in Scientific reports (15-08-2017)
    “…There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this…”
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    Vitamin D receptor gene polymorphisms are associated with obesity and inflammosome activity by Al-Daghri, Nasser M, Guerini, Franca R, Al-Attas, Omar S, Alokail, Majed S, Alkharfy, Khalid M, Draz, Hossam M, Agliardi, Cristina, Costa, Andrea S, Saulle, Irma, Mohammed, Abdul Khader, Biasin, Mara, Clerici, Mario

    Published in PloS one (14-07-2014)
    “…To explore the mechanisms underlying the suggested role of the vitamin D/vitamin D receptor (VDR) complex in the pathogenesis of obesity we performed genetic…”
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    Irisin as a predictor of glucose metabolism in children: sexually dimorphic effects by Al-Daghri, Nasser M., Alkharfy, Khalid M., Rahman, Shakilur, Amer, Osama E., Vinodson, Benjamin, Sabico, Shaun, Piya, Milan K., Harte, Alison L., McTernan, Philip G., Alokail, Majed S., Chrousos, George P.

    Published in European journal of clinical investigation (01-02-2014)
    “…Background Irisin, a novel myokine, increases energy expenditure and glucose tolerance and, thus, improves carbohydrate homeostasis in humans. This hormone has…”
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    Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing by Krishnaswamy, Soundararajan, Mohammed, Abdul Khader, Tripathi, Gyanendra, Alokail, Majed S, Al-Daghri, Nasser M

    Published in BMC cancer (09-11-2017)
    “…Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d'origine nantais (RON) receptor is a…”
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    Associations of zinc-α-2-glycoprotein with metabolic syndrome and its components among adult Arabs by Alenad, Amal M., Alkaltham, Lamya F., Sabico, Shaun, Khattak, Malak N. K., Wani, Kaiser, Al-Daghri, Nasser M., Alokail, Majed S.

    Published in Scientific reports (22-03-2022)
    “…Epidemiological studies suggest that the Zinc-α-2-glycoprotein (ZAG) plays significant physiological roles. In this study we investigate whether ZAG could be…”
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    Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes by Wani, Kaiser, Alfawaz, Hanan, Alnaami, Abdullah M, Sabico, Shaun, Khattak, Malak Nawaz Khan, Al-Attas, Omar, Alokail, Majed S, Alharbi, Mohammed, Chrousos, George, Kumar, Sudhesh, Al-Daghri, Nasser M

    Published in Nutrients (12-02-2020)
    “…This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the…”
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    Metabolic Syndrome in Arab Adults with Low Bone Mineral Density by Wani, Kaiser, Yakout, Sobhy M, Ansari, Mohammed Ghouse Ahmed, Sabico, Shaun, Hussain, Syed Danish, Alokail, Majed S, Sheshah, Eman, Aljohani, Naji J, Al-Saleh, Yousef, Reginster, Jean-Yves, Al-Daghri, Nasser M

    Published in Nutrients (21-06-2019)
    “…There are discrepancies in the reports on the association of metabolic syndrome (MetS) and its components with bone mineral density (BMD) and hence more…”
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    Anticancer potential of gold nanoparticles (AuNPs) using a battery of in vitro tests by Alafaleq, Nouf Omar, Alomari, Alya, Khan, Mohd Shahnawaz, Shaik, Gouse M., Hussain, Afzal, Ahmed, Faheem, Hassan, Iftekhar, M. Alhazza, Ibrahim, Alokail, Majed S., Alenad, Amal Majed H., Jabir, Nasimudeen R., Tabrez, Shams

    Published in Nanotechnology reviews (Berlin) (31-12-2022)
    “…This study synthesized gold nanoparticles (AuNPs) using a facile microwave-assisted chemical route and evaluated them as potential anticancer candidates…”
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    Early-Pregnancy Metabolic Syndrome and Subsequent Incidence in Gestational Diabetes Mellitus in Arab Women by Wani, Kaiser, Sabico, Shaun, Alnaami, Abdullah M, Al-Musharaf, Sara, Fouda, Mona A, Turkestani, Iqbal Z, Al-Ajlan, Abdulrahman, Alshingetti, Naemah M, Alokail, Majed S, Al-Daghri, Nasser M

    Published in Frontiers in endocrinology (Lausanne) (27-02-2020)
    “…This study aimed to investigate the association between components of metabolic syndrome (MetS) at first trimester and development of Gestational diabetes…”
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    Association of Vitamin B12 with Pro-Inflammatory Cytokines and Biochemical Markers Related to Cardiometabolic Risk in Saudi Subjects by Al-Daghri, Nasser M, Rahman, Shakilur, Sabico, Shaun, Yakout, Sobhy, Wani, Kaiser, Al-Attas, Omar S, Saravanan, Ponnusamy, Tripathi, Gyanendra, McTernan, Philip G, Alokail, Majed S

    Published in Nutrients (06-09-2016)
    “…This study aimed to examine the relationship between changes in systemic vitamin B12 concentrations with pro-inflammatory cytokines, anthropometric factors and…”
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    Effect of physical activity and sun exposure on vitamin D status of Saudi children and adolescents by Al-Othman, Abdulaziz, Al-Musharaf, Sara, Al-Daghri, Nasser M, Krishnaswamy, Soundararajan, Yusuf, Deqa S, Alkharfy, Khalid M, Al-Saleh, Yousef, Al-Attas, Omar S, Alokail, Majed S, Moharram, Osama, Sabico, Shaun, Chrousos, George P

    Published in BMC pediatrics (03-07-2012)
    “…Accumulating evidence suggests an increased prevalence of vitamin D deficiency in the Middle East. In this context, we aimed to determine whether the…”
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    The effect of novel antihypertensive drug valsartan on lysozyme aggregation: A combined in situ and in silico study by Altwaijry, Nojood, Almutairi, Ghaliah S., Khan, Mohd Shahhnawaz, Alokail, Majed S., Alafaleq, Nouf, Ali, Rizwan

    Published in Heliyon (01-04-2023)
    “…Protein misfolding can result in amyloid fiber aggregation, which is associated with various types of diseases. Therefore, preventing or treating abnormally…”
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    Polycyclic aromatic hydrocarbon exposure and pediatric asthma in children: a case-control study by Al-Daghri, Nasser M, Alokail, Majed S, Abd-Alrahman, Sherif H, Draz, Hossam M, Yakout, Sobhy M, Clerici, Mario

    Published in Environmental health (03-01-2013)
    “…Bronchial asthma is one of the most prevalent diseases in Arab children. Environmental pollution has been suggested to be considered causative of asthma, nasal…”
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    Vitamin D Supplementation Is Associated with Increased Glutathione Peroxidase-1 Levels in Arab Adults with Prediabetes by Ansari, Mohammed Ghouse Ahmed, Sabico, Shaun, Clerici, Mario, Khattak, Malak Nawaz Khan, Wani, Kaiser, Al-Musharaf, Sara, Amer, Osama Emam, Alokail, Majed S, Al-Daghri, Nasser M

    Published in Antioxidants (29-01-2020)
    “…Vitamin D supplementation may be used to lower oxidative stress. This interventional study aimed to investigate the effects of vitamin D supplementation on…”
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