Search Results - "Alokail, Majed S"
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Effects of a multi-strain probiotic supplement for 12 weeks in circulating endotoxin levels and cardiometabolic profiles of medication naïve T2DM patients: a randomized clinical trial
Published in Journal of translational medicine (11-12-2017)“…The present randomized clinical trial characterized the beneficial effects of a multi-strain probiotics supplementation on improving circulating endotoxin…”
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Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (Riyadh cohort 2): a decade of an epidemic
Published in BMC medicine (20-06-2011)“…Follow-up epidemiologic studies are needed to assess trends and patterns of disease spread. No follow-up epidemiologic study has been done in the Kingdom of…”
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3
Binding Studies of Caffeic and p-Coumaric Acid with α-Amylase: Multispectroscopic and Computational Approaches Deciphering the Effect on Advanced Glycation End Products (AGEs)
Published in Molecules (Basel, Switzerland) (21-06-2022)“…Alpha-amylase (α-amylase) is a key player in the management of diabetes and its related complications. This study was intended to have an insight into the…”
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Effect of Antihypertensive Drug (Chlorothiazide) on Fibrillation of Lysozyme: A Combined Spectroscopy, Microscopy, and Computational Study
Published in International journal of molecular sciences (01-02-2023)“…Amyloid fibrils abnormally accumulate together in the human body under certain conditions, which can result in lethal conditions. Thus, blocking this…”
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5
Anticancer Potential of Biogenic Silver Nanoparticles: A Mechanistic Study
Published in Pharmaceutics (12-05-2021)“…The continuous loss of human life due to the paucity of effective drugs against different forms of cancer demands a better/noble therapeutic approach. One…”
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Agitation does not induce fibrillation in reduced hen egg‐white lysozyme at physiological temperature and pH
Published in Journal of molecular recognition (01-06-2023)“…Several proteins and peptides tend to form an amyloid fibril, causing a range of unrelated diseases, from neurodegenerative to certain types of cancer. In the…”
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Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients
Published in Scientific reports (15-08-2017)“…There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this…”
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Vitamin D receptor gene polymorphisms are associated with obesity and inflammosome activity
Published in PloS one (14-07-2014)“…To explore the mechanisms underlying the suggested role of the vitamin D/vitamin D receptor (VDR) complex in the pathogenesis of obesity we performed genetic…”
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Irisin as a predictor of glucose metabolism in children: sexually dimorphic effects
Published in European journal of clinical investigation (01-02-2014)“…Background Irisin, a novel myokine, increases energy expenditure and glucose tolerance and, thus, improves carbohydrate homeostasis in humans. This hormone has…”
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10
Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing
Published in BMC cancer (09-11-2017)“…Altered expression of receptor tyrosine kinases (RTKs) is a major driver of growth and metastasis of cancers. Recepteur d'origine nantais (RON) receptor is a…”
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Associations of zinc-α-2-glycoprotein with metabolic syndrome and its components among adult Arabs
Published in Scientific reports (22-03-2022)“…Epidemiological studies suggest that the Zinc-α-2-glycoprotein (ZAG) plays significant physiological roles. In this study we investigate whether ZAG could be…”
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Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes
Published in Nutrients (12-02-2020)“…This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the…”
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13
Metabolic Syndrome in Arab Adults with Low Bone Mineral Density
Published in Nutrients (21-06-2019)“…There are discrepancies in the reports on the association of metabolic syndrome (MetS) and its components with bone mineral density (BMD) and hence more…”
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14
Anticancer potential of gold nanoparticles (AuNPs) using a battery of in vitro tests
Published in Nanotechnology reviews (Berlin) (31-12-2022)“…This study synthesized gold nanoparticles (AuNPs) using a facile microwave-assisted chemical route and evaluated them as potential anticancer candidates…”
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15
Early-Pregnancy Metabolic Syndrome and Subsequent Incidence in Gestational Diabetes Mellitus in Arab Women
Published in Frontiers in endocrinology (Lausanne) (27-02-2020)“…This study aimed to investigate the association between components of metabolic syndrome (MetS) at first trimester and development of Gestational diabetes…”
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Association of Vitamin B12 with Pro-Inflammatory Cytokines and Biochemical Markers Related to Cardiometabolic Risk in Saudi Subjects
Published in Nutrients (06-09-2016)“…This study aimed to examine the relationship between changes in systemic vitamin B12 concentrations with pro-inflammatory cytokines, anthropometric factors and…”
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Effect of physical activity and sun exposure on vitamin D status of Saudi children and adolescents
Published in BMC pediatrics (03-07-2012)“…Accumulating evidence suggests an increased prevalence of vitamin D deficiency in the Middle East. In this context, we aimed to determine whether the…”
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The effect of novel antihypertensive drug valsartan on lysozyme aggregation: A combined in situ and in silico study
Published in Heliyon (01-04-2023)“…Protein misfolding can result in amyloid fiber aggregation, which is associated with various types of diseases. Therefore, preventing or treating abnormally…”
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Polycyclic aromatic hydrocarbon exposure and pediatric asthma in children: a case-control study
Published in Environmental health (03-01-2013)“…Bronchial asthma is one of the most prevalent diseases in Arab children. Environmental pollution has been suggested to be considered causative of asthma, nasal…”
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Vitamin D Supplementation Is Associated with Increased Glutathione Peroxidase-1 Levels in Arab Adults with Prediabetes
Published in Antioxidants (29-01-2020)“…Vitamin D supplementation may be used to lower oxidative stress. This interventional study aimed to investigate the effects of vitamin D supplementation on…”
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