Search Results - "Alobaida, Ahmed"

Anti-Cancer Drug Solubility Development within a Green Solvent: Design of Novel and Robust Mathematical Models Based on Artificial Intelligence by Huwaimel, Bader, Alobaida, Ahmed

“…Nowadays, supercritical CO2(SC-CO2) is known as a promising alternative for challengeable organic solvents in the pharmaceutical industry. The mathematical…”
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Delafloxacin-Capped Gold Nanoparticles (DFX-AuNPs): An Effective Antibacterial Nano-Formulation of Fluoroquinolone Antibiotic by Abu Lila, Amr Selim, Huwaimel, Bader, Alobaida, Ahmed, Hussain, Talib, Rafi, Zeeshan, Mehmood, Khalid, Abdallah, Marwa H, Hagbani, Turki Al, Rizvi, Syed Mohd Danish, Moin, Afrasim, Ahmed, Abobakr F

“…New antibiotics are seen as ‘drugs of last resort’ against virulent bacteria. However, development of resistance towards new antibiotics with time is a…”
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Manganese chloride (MnCl2) induced novel model of Parkinson’s disease in adult Zebrafish; Involvement of oxidative stress, neuroinflammation and apoptosis pathway by Nadig, Abhishek.P.R., Huwaimel, Bader, Alobaida, Ahmed, Khafagy, El-Sayed, Alotaibi, Hadil Faris, Moin, Afrasim, Lila, Amr Selim Abu, Suman, M, Sahyadri, Krishna, K.L.

“…Parkinson’s disease (PD) is a progressive neurodegenerative disorder imposing a severe health and socioeconomic burden worldwide. Existing pharmacological…”
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Development a novel robust method to enhance the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug based on machine-learning by Abdelbasset, Walid Kamal, Elkholi, Safaa M., Ismail, Khadiga Ahmed, Alshehri, Sameer, Alobaida, Ahmed, Huwaimel, Bader, Alatawi, Ahmed D., Alsubaiyel, Amal M., Venkatesan, Kumar, Abourehab, Mohammed A. S.

“…Accurate specification of the drugs’ solubility is known as an important activity to appropriately manage the supercritical impregnation process. Over the last…”
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Phytochemical composition, in vitro cytotoxicity, and in silico docking properties of Tamarix tetragyna L by Huwaimel, Bader, Younes, Kareem M., Abouzied, Amr S., Elkashlan, Akram M., Alheibshy, Fawaz N., Alobaida, Ahmed, Turki, Abdullah, Alquwaiay, Saleh A., Alqahatani, Naif, Alsuwayagh, Sulaiman A.

“…Tamarix tetragyna is a plant grows in Mediterranean area and some Arab countries. It possesses numerous medicinal values. Purpose of our study is to explore…”
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Development of GBRT Model as a Novel and Robust Mathematical Model to Predict and Optimize the Solubility of Decitabine as an Anti-Cancer Drug by Abdelbasset, Walid Kamal, Elsayed, Shereen H, Alshehri, Sameer, Huwaimel, Bader, Alobaida, Ahmed, Alsubaiyel, Amal M, Alqahtani, Abdulsalam A, El Hamd, Mohamed A, Venkatesan, Kumar, AboRas, Kareem M, Abourehab, Mohammed A. S

“…The efficient production of solid-dosage oral formulations using eco-friendly supercritical solvents is known as a breakthrough technology towards developing…”
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Ceftriaxone Mediated Synthesized Gold Nanoparticles: A Nano-Therapeutic Tool to Target Bacterial Resistance by Alshammari, Farhan, Alshammari, Bushra, Moin, Afrasim, Alamri, Abdulwahab, Al Hagbani, Turki, Alobaida, Ahmed, Baker, Abu, Khan, Salman, Rizvi, Syed Mohd Danish

“…Ceftriaxone has been a part of therapeutic regime for combating some of the most aggressive bacterial infections in the last few decades. However, increasing…”
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University Students' Self-Medication Practices and Pharmacists' Role: A Cross-Sectional Survey in Hail, Saudi Arabia by Alshammari, Farhan, Alobaida, Ahmed, Alshammari, Abdulhadi, Alharbi, Atheer, Alrashidi, Adel, Almansour, Asma, Alremal, Amal, Khan, Kashif Ullah

“…Self-medication is an important issue for health authorities around the world. It is also a common practice among university students. This study aimed to…”
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Dithymoquinone Analogues as Potential Candidate(s) for Neurological Manifestation Associated with COVID-19: A Therapeutic Strategy for Neuro-COVID by Moin, Afrasim, Huwaimel, Bader, Alobaida, Ahmed, Break, Mohammed Khaled Bin, Iqbal, Danish, Unissa, Rahamat, Jamal, Qazi Mohammad Sajid, Hussain, Talib, Sharma, Dinesh C., Rizvi, Syed Mohd Danish

“…The COVID-19 era has prompted several researchers to search for a linkage between COVID-19 and its associated neurological manifestation. Toll-like receptor 4…”
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Bioactive principles, anti-diabetic, and anti-ulcer activities of Ducrosia anethifolia Boiss leaves from the Hail region, Saudi Arabia by Unissa Syed, Rahamat, Moni, Sivakumar S., Huwaimel, Bader, Alobaida, Ahmed, Abdulkareem Almarshdi, Afnan, S. Abouzied, Amr, S.Abu Lila, Amr, Abdallah, Marwa H., Banu, Humera, Abdul Hadi, Mohd, E. El-Horany, Hemat, Ibrahim Abdelwahab, Siddig, Taha, Manal Mohamed Elhassan

“…This work aimed to identify the bioactive constituents of Ducrosia anethifolia Boiss eaves through cold methanolic extract. The GC–MS study of cold methanolic…”
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Analysis of enhancing drug bioavailability via nanomedicine production approach using green chemistry route: Systematic assessment of drug candidacy by Alobaida, Ahmed, Huwaimel, Bader

“…•Model-based analysis of drug solubility in supercritical CO2.•Comparisons of several machine learning performance in description of solubility.•Validation of…”
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Newer approaches and novel drugs for inhalational therapy for pulmonary arterial hypertension by Keshavarz, Ali, Kadry, Hossam, Alobaida, Ahmed, Ahsan, Fakhrul

“…: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by remodeling of small pulmonary arteries leading to increased pulmonary…”
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Targeting endothelial permeability in the EPR effect by Lahooti, Behnaz, Akwii, Racheal G., Zahra, Fatema Tuz, Sajib, Md Sanaullah, Lamprou, Margarita, Alobaida, Ahmed, Lionakis, Michail S., Mattheolabakis, George, Mikelis, Constantinos M.

“…The characteristics of the primary tumor blood vessels and the tumor microenvironment drive the enhanced permeability and retention (EPR) effect, which confers…”
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A review on taste masked multiparticulate dosage forms for paediatric by AL-Japairai, Khater, Hamed Almurisi, Samah, Almonem Doolaanea, Abd, Mahmood, Syed, Alheibshy, Fawaz, Alobaida, Ahmed, Abdul-Halim, Nadiya, Chatterjee, Bappaditya

“…[Display omitted] Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the…”
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Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects by Al-Hilal, Taslim A., Hossain, Mohammad Anwar, Alobaida, Ahmed, Alam, Farzana, Keshavarz, Ali, Nozik-Grayck, Eva, Stenmark, Kurt R., German, Nadezhda A., Ahsan, Fakhrul

“…ROCK, one of the downstream regulators of Rho, controls actomyosin cytoskeleton organization, stress fiber formation, smooth muscle contraction, and cell…”
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CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil by Keshavarz, Ali, Alobaida, Ahmed, McMurtry, Ivan F, Nozik-Grayck, Eva, Stenmark, Kurt R, Ahsan, Fakhrul

“…Here, we sought to elucidate the role of CAR (a cyclic peptide) in the accumulation and distribution of fasudil, a drug for pulmonary arterial hypertension…”
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Analyzing energetics and dynamics of hepatitis C virus polymerase interactions with marine bacterial compounds: a computational study by Alobaida, Ahmed, Abouzied, Amr S, Younes, Kareem M, Alzhrani, Rami M, Alsaab, Hashem O, Huwaimel, Bader

“…Hepatitis C Virus (HCV) is a significant health concern affecting a large portion of the global population and is a major cause of acute liver diseases,…”
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Formulation and evaluation of inhaled Sildenafil-loaded PLGA microparticles for treatment of pulmonary arterial hypertension (PAH): A novel high drug loaded formulation and scalable process via hot melt extrusion technology (Part Ⅰ) by Almutairi, Mashan, Hefnawy, Amr, Almotairy, Ahmed, Alobaida, Ahmed, Alyahya, Mohammed, Althobaiti, Abdulmajeed, Adel Ali Youssef, Ahmed, Elkanayati, Rasha M., Ashour, Eman A., Smyth, Hugh D.C., Repka, Michael A.

“…[Display omitted] In recent years, several techniques were employed to develop a local sustained pulmonary delivery of sildenafil citrate (SC) as an…”
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Synthesis of novel series of heterocyclic compounds having two azoles against Methicillin-sensitive Staphylococcus aureus by Alamri, Abdulwahab, Alafnan, Ahmed, Huwaimel, Bader, Abouzied, Amr S., Alanazi, Jowaher, Alghamdi, Adel, Alrofaidi, Mohammad A, Alanazi, Muteb S, Alshehri, Ahmed, Hagbani, Turki Al, Alobaida, Ahmed, Younes, Kareem M., Farghaly, Thoraya A.

“…•Thiazole-linked-thiadiazoles and dithiazoles were prepared from the reaction of thiazolethiosemicarbazone derivatives with α-haloketones.•All structures of…”
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Enhancing drugs bioavailability using nanomedicine approach: Predicting solubility of Tolmetin in supercritical solvent via advanced computational techniques by Abourehab, Mohammed A.S., Alshehri, Sameer, Huwaimel, Bader, Alamri, Ali H., Alzhrani, Rami M., Alobaida, Ahmed, Kotb, Hossam, Alsubaiyel, Amal M., Yasmin, Sabina, Venkatesan, Kumar, Salah Al-Shati, Ahmed

“…•Developing advanced models for estimation of pharmaceutical solubility.•Understanding the role of pressure and temperature on the drug solubility.•Validation…”
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