Search Results - "Almulla, Fahd"

Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus by Al Khaldi, Rasha, Mojiminiyi, Olusegun, AlMulla, Fahd, Abdella, Nabila

“…Previous Studies have mapped putative loci that may probably regulate leukocyte telomere length (LTL). The strongest associations with LTL were reported for…”
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Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea by Al-Terki, Abdulmohsen, Abu-Farha, Mohamed, AlKhairi, Irina, Cherian, Preethi T, Sriraman, Devarajan, Shyamsundar, Ambika, Ali, Shamsha, Almulla, Fahd, Tuomilehto, Jaakko, Abubaker, Jehad A

“…Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is…”
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475-P: Peroxisome Proliferator-Activated Receptor Delta (PPARδ)-A Key Modulator in the Pathogenesis of Diabetes Mellitus and Mycobacterium Tuberculosis Comorbidity by Alsaeed, Halemah, Almulla, Fahd, Ahmad, Rasheed, Alrashed, Fatema

“…The interplay between lipid metabolism and immune response in macrophages plays a pivotal role in various infectious diseases, notably tuberculosis (TB)…”
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41-LB: Regular Physical Activity Plays a Crucial Role in Improving the Anti-inflammatory Status of Healthy Individuals by Modulating TLR2 Expression by BAHMAN, FATEMAH, ALSAEED, HALEMAH, ALBELOUSHI, SHAIMA, ALMULLA, FAHD, AHMAD, RASHEED, ALRASHED, FATEMA

“…Toll-like receptors (TLRs) are dominant components of the innate immune system and have been targeted for therapeutic drug development for several inflammatory…”
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2001-LB: Small RNA-seq Identifies Distinct miRNAs Involved in Familial and Sporadic Type 1 Diabetes Cases from Kuwait by Nizam, Rasheeba, Malik, Md Zubbair, Jacob, Sindhu, Koistinen, Heikki A, Tuomilehto, Jaakko, Alkandari, Hessa, Almulla, Fahd, Thangavel, Alphonse T

“…Clinical diagnosis of Type 1 Diabetes (T1D) has been hallmarked by the presence of serum biomarkers such as circulating autoantibodies and c-peptide; however,…”
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1143-P: Early Aged Mice Stay Metabolically Stable with High-Fat Diet by Bahman, Fatemah, Kochumon, Shihab P, Alrashed, Fatema, Abukhalaf, Nermeen A, Thomas, Reeby S, Almulla, Fahd, Ahmad, Rasheed

“…The relationship between obesity, aging, and the risk of metabolic diseases is a crucial area of study. This research focuses on understanding how aging…”
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1480-P: Mitochondrial Haplogroup H Is Protective against Type 2 Diabetes in Arabs from Gulf Region by DASHTI, MOHAMMED H., ALI, NASER, ALSALEH, HUSSAIN, NIZAM, RASHEEBA, ALMULLA, FAHD, THANGAVEL, ALPHONSE T.

“…Background: Mitochondrial dysfunction is implicated in the pathogenesis of type 2 diabetes (T2D) via impaired glucose-stimulated insulin secretion in…”
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1112-P: Soluble Suppression of Tumorigenicity 2 Is Directly Correlated with Body Fat, Metabolic Dysfunction, and Inflammation in Children and Adolescents by HASAN, AMAL, KOCHUMON, SHIHAB P., ALBASIRI, IMAN D., ALMULLA, FAHD, AHMAD, RASHEED

“…Purpose: Childhood obesity is a major risk factor for chronic diseases such as type 2 diabetes (T2D) and cardiovascular disease. Elevated soluble suppression…”
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1586-P: Association between PCSK7 Levels and NAFLD Severity in KADEM Study by Qaddoumi, Mohammad, Abubaker, Jehad, Al-Khairi, Irina, Cherian, Preethi T, Sriraman, Devarajan, Thangavel, Alphonse T, Channanath, Arshad M, Abdul-Ghani, Muhammad, Almulla, Fahd, Abu-Farha, Mohamed

“…Introduction: The increased obesity rates worldwide are associated with increased rates of Non-alcoholic fatty liver disease (NAFLD). Proprotein Convertase…”
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1486-P: Role of HLA Class I Gene Alleles and Haplotypes in Type 1 Diabetes in Kuwaiti Children by Dashti, Mohammed H, Malik, MD Zubbair, Nizam, Rasheeba, Jacob, Sindhu, Alkandari, Hessa, Alozairi, Ebaa S, Thangavel, Alphonse T, Almulla, Fahd

“…Introduction & Objective: HLA class I genes have a role in influencing immune response and self-tolerance as they bind and present antigens to T cells. Allelic…”
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173-LB: Circulating Calprotectin Is Increased in Children with T1D and Obesity—Implications for T1D Progression and Outcome by HASAN, AMAL, KOCHUMON, SHIHAB P., ALBASIRI, IMAN D., ALBELOUSHI, SHAIMA, ALOZAIRI, EBAA S., ALMULLA, FAHD

“…Purpose: Circulating calprotectin is elevated in inflammatory disorders and is a biomarker of severity in inflammatory rheumatic and bowel diseases…”
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1674-P: Stearate Potentiates MIP-1a Production with TNF-a via TLR4/TBK1/IKKe /IRF3 Signal Axis: Significance for Insulin Resistance by AHMAD, RASHEED, KOCHUMON, SHIHAB P., AREFANIAN, HOSSEIN, ALMULLA, FAHD

“…Increased levels of plasma free fatty acids (FAs) are an important contributor to chronic inflammation, insulin resistance and other obesity-related…”
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1600-P: Sunflower Oil HFD Feeding in Mice Leads to Gut Dysbiosis, Mild Steatohepatitis, and Impaired Glycemic Control by Sindhu, Sardar Tak, Bahman, Fatemah, Malik, Mohammad Zubbair, Arefanian, Hossein, Alrashed, Fatema, Nizam, Rasheeba, Kochumon, Shihab P, Thomas, Reeby S, Albeloushi, Shaima, Hasan, Amal, Abu-Farha, Mohamed, Madhoun, Ashraf Al, Thangavel, Alphonse T, Almulla, Fahd, Ahmad, Rasheed

“…Introduction & Objective: High-fat diets (HFDs) influence gut microbiota and promote obesity & metabolic dysregulation. Dietary sucrose is a co-player in…”
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1501-P: Four Loci, Four Fates-Differential Regulation of IRF5 Promoter in Prodiabetogenic Stress by Al Madhoun, Ashraf, Arefanian, Hossein, Kochumon, Shihab P, Akhter, Nadeem, Wilson, Ajit, Albeloushi, Shaima, Alrashed, Fatema, Bahman, Fatemah, Al-Mansour, Nourah, Alzaid, Fawaz, Almulla, Fahd, Ahmad, Rasheed, Sindhu, Sardar T

“…Introduction: Interferon regulatory factor (IRF)-5 is a transcription factor sitting at the crossroads of diverse cell processes. Emerging evidence supports…”
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162-OR: Sustained TNF-a Transcription Triggered in Obesity through H3K9/K18 Acetylation Is Associated with Metabolic Impairments by Ahmad, Rasheed, Bahman, Fatemah, Kochumon, Shihab P, Jacob, Texy K, Alrashed, Fatema, Wilson, Ajit, Arefanian, Hossein, Thomas, Reeby S, Akhter, Nadeem, Al-Mansour, Nourah, Albeloushi, Shaima, Al Madhoun, Ashraf, Sindhu, Sardar Tak, Alzaid, Fawaz, Almulla, Fahd

“…Obesity-induced metabolic inflammation contributes to the development of various metabolic disorders and can be induced by the consumption of high-fat diets…”
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1278-P: The Tale of Caveolin 1 rs1997623 Variant in Obesity and Metabolic Syndrome by MADHOUN, ASHRAF AL, HADDAD, DANIA, KOCHUMON, SHIHAB P., NIZAM, RASHEEBA, JACOB, SINDHU, SINDHU, SARDAR T., AHMAD, RASHEED, ALMULLA, FAHD

“…We Have previously established that caveolin-1 (CAV1) rs1997623 C/A variant is associated with metabolic syndrome in obese children (PMID: 30622557) and adults…”
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478-P: GALNT2 Variant Associates with Increased ANGPTL3 Circulation Level and Obesity by THANGAVEL, ALPHONSE T., ABU-FARHA, MOHAMED, HEBBAR, PRASHANTHA, QADDOUMI, MOHAMMAD G., ALMULLA, FAHD, ABUBAKER, JEHAD

“…Background: Polypeptide N-Acetylgalactosaminyltransferase 2 (GALNT2) gene has been associated with serum lipid levels, insulin resistance, and adipogenesis…”
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54-LB: Distinct Mechanisms Are Responsible for the Increase in Endogenous Glucose Production and Ketone Formation following Empagliflozin in T2DM Patients by ABDELGANI, SIHAM, ADAMS, JOHN M., DANIELE, GIUSEPPE, ALMULLA, FAHD, DEFRONZO, RALPH A., ABDUL-GHANI, MUHAMMAD, ABU-FARHA, MOHAMED, DEL PRATO, STEFANO

“…Aim: To examine the mechanisms responsible for the increase in glucose and ketone production caused by SGLT2 inhibition with empagliflozin in T2DM patients…”
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75-OR: IL-6R (Trans Signaling) Is a Major Modulator of Reverse Cholesterol Transport in Lipid-Laden Macrophages by ALRASHED, FATEMA, ALZAQQAH, FATEMAH, MADHOUN, ASHRAF AL, ALQABANDI, RAWAN, SINDHU, SARDAR T., ALMULLA, FAHD, AHMAD, RASHEED

“…The onset of obesity is vastly associated with low levels of high-density lipoprotein cholesterol (HDL-C) , which predisposes to cardiovascular diseases…”
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1288-P: Increased Adipose Tissue Expression of IL-23 and Its Association with Inflammation in Individuals with High LDL Cholesterol by AHMAD, RASHEED, KOCHUMON, SHIHAB P., HASAN, AMAL, SINDHU, SARDAR T., AREFANIAN, HOSSEIN, ALRASHED, FATEMA, ALMULLA, FAHD

“…Obesity induced chronic low-grade inflammation is a central risk factor for the development of metabolic syndrome. It has been well documented that high LDL-c…”
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