Search Results - "Almquist, Susan J."

Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes by Jain, Jugnu, Almquist, Susan J., Ford, Pamella J., Shlyakhter, Dina, Wang, Yongping, Nimmesgern, Elmar, Germann, Ursula A.

“…The enzyme inosine monophosphate dehydrogenase (IMPDH) catalyzes the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Inhibition of IMPDH…”
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Characterization of pharmacological efficacy of VX-148, a new, potent immunosuppressive inosine 5'-monophosphate dehydrogenase inhibitor by Jain, Jugnu, Almquist, Susan J, Heiser, Angela D, Shlyakhter, Dina, Leon, Eduardo, Memmott, Christine, Moody, Cameron Stuver, Nimmesgern, Elmar, Decker, Caroline

“…Inosine 5'-monophosphate dehydrogenase (IMPDH) enzyme catalyzes the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Proliferation of…”
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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease by PERNI, Robert B, ALMQUIST, Susan J, HEISER, Angela, KALKERI, Gururaj, KOLACZKOWSKI, Elaine, KAI LIN, LUONG, Yu-Ping, GOVINDA RAO, B, TAYLOR, William P, THOMSON, John A, TUNG, Roger D, YUNYI WEI, BYRN, Randal A, KWONG, Ann D, CHAO LIN, CHANDORKAR, Gurudatt, CHATURVEDI, Pravin R, COURTNEY, Lawrence F, DECKER, Caroline J, DINEHART, Kirk, GATES, Cynthia A, HARBESON, Scott L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent by Jain, J, Almquist, S J, Shlyakhter, D, Harding, M W

“…Inosine monophosphate dehydrogenase (IMPDH) is an essential rate-limiting enzyme in the purine metabolic pathway, catalyzing the de novo synthesis of guanine…”
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Antibodies Against Membrane Interleukin 1α Activate Accessory Cells to Stimulate Proliferation of T Lymphocytes by Eugui, Elsie M., Almquist, Susan J.

“…Some monoclonal antibodies (mAbs) against interleukin (IL) 1α have been found to activate antigen-presenting cells (APC, human peripheral blood monocytes and B…”
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