Prevalence of undiagnosed COPD in male patients with coronary artery disease: a cross-sectional study in Jordan

Prevalence of undiagnosed COPD in male patients with coronary artery disease: a cross-sectional study in Jordan

COPD and coronary artery disease (CAD) are common chronic diseases with shared risk factors. COPD continues to be largely underdiagnosed and undertreated. We aimed to describe the prevalence and predictors of undiagnosed COPD in Jordanian men with CAD. In a cross-sectional study conducted at a refer...

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Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease Vol. 13; pp. 2759 - 2766
Main Authors: Khassawneh, Basheer Y, Samrah, Shaher M, Jarrah, Mohamad I, Ibdah, Rasheed K, Ibnian, Ali M, Almistarehi, Abdelhameed W, Zghayer, Aseel A, Abuqudairi, Saddam I, Khader, Yousef S
Format: Journal Article
Language:English
Published: New Zealand Dove Medical Press Limited 01-01-2018
Dove Medical Press Ltd
Dove
Dove Medical Press
Subjects:
Age
Aged
airflow limitation
Angiography
Asthma
Body mass index
Bronchitis
Cardiac patients
Cardiovascular disease
Catheterization
Chronic diseases
Chronic obstructive pulmonary disease
Cigarettes
COPD
Coronary Artery Disease - diagnosis
Coronary Artery Disease - epidemiology
coronary catheterization
Coronary heart disease
Coronary vessels
Cross-Sectional Studies
Developing countries
Diagnostic imaging
Dyspnea
Forced Expiratory Volume
Humans
Jordan - epidemiology
LDCs
Lung diseases
Male
Medical imaging
Medical research
Medicine, Experimental
Middle Aged
Morbidity
Mortality
Original Research
Patients
Percutaneous Coronary Intervention
Prevalence
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary Disease, Chronic Obstructive - physiopathology
Regression analysis
Respiratory symptoms
Risk Factors
Smokers - statistics & numerical data
Smoking
Spirometry
Vein & artery diseases
Jordan
Middle East
United States > US
airflow limitation
cardiovascular disease
coronary catheterization
spirometry
COPD
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Description
Summary:COPD and coronary artery disease (CAD) are common chronic diseases with shared risk factors. COPD continues to be largely underdiagnosed and undertreated. We aimed to describe the prevalence and predictors of undiagnosed COPD in Jordanian men with CAD. In a cross-sectional study conducted at a referral center in Jordan, male patients who underwent coronary angiography for suspected CAD and reported $10 pack-year of cigarette smoking were recruited. Pre- and post-bronchodilator spirometry was undertaken for all participants, and COPD was defined as post-bronchodilator FEV /FVC <70%. The finding of ≥50% coronary luminal narrowing confirmed the presence of CAD. Spirometry was undertaken for 376 men with mean age of 56.02±10.55 years, and 72.6% were active cigarettes smokers with a mean pack-year of 55.89±34.25. A CAD diagnosis was confirmed in 300 (79.8%) men. Spirometric criteria for COPD were met in 76 (15.7%) patients, of whom 91.5% were not previously diagnosed. COPD-related symptoms were common: chronic cough (44.4%), dyspnea (66.2%), and wheezes (27.9%). COPD was more common in patients with (18.0%) compared to patients without (6.6%) CAD ( =0.014). Multivariate logistic regression showed that the risk of COPD was higher in patients with CAD (OR 3.16, 95% CI, 1.10-9.09, =0.033) and in those with chronic bronchitis (OR 13.07, 95% CI, 6.69-25.52, <0.001). There was a high prevalence of COPD among male patients with CAD and most were underdiagnosed despite having respiratory symptoms. Male smokers with CAD and respiratory symptoms should be evaluated for airflow limitation and the presence of COPD.
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ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S172679