Search Results - "Almeida, L. C."
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Social-pair judgment bias testing in slow-growing broiler chickens raised in low- or high-complexity environments
Published in Scientific reports (09-06-2023)“…Impacts of environmental complexity on affective states in slow-growing broiler chickens ( Gallus gallus domesticus ) are unknown. Chickens’ performance in…”
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IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy
Published in Annals of the rheumatic diseases (01-09-2010)“…Interleukin 33 (IL-33) is a new member of the IL-1 family of cytokines which signals via its receptor, ST2 (IL-33R), and has an important role in Th2 and mast…”
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Chronic toxicity and environmental risk assessment of antivirals in Ceriodaphnia dubia and Raphidocelis subcapitata
Published in Water science and technology (01-10-2021)“…Antiviral drugs are a class of medications used for treating viral infections. Due to their widespread use, especially in cases of pandemics and limited human…”
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Presence of anti-Müllerian hormone (AMH) during follicular development in the porcine ovary
Published in PloS one (31-07-2018)“…Anti-Müllerian hormone (AMH) is expressed by granulosa cells of developing follicles and plays an inhibiting role in the cyclic process of follicular…”
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The interaction of dengue virus capsid protein with negatively charged interfaces drives the in vitro assembly of nucleocapsid-like particles
Published in PloS one (01-03-2022)“…Dengue virus (DENV) causes a major arthropod-borne viral disease, with 2.5 billion people living in risk areas. DENV consists in a 50 nm-diameter enveloped…”
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On the caveats of a multiplex test for SARS-CoV-2 to detect seroconversion after infection or vaccination
Published in Scientific reports (20-06-2022)“…The Covid-19 pandemic, caused by SARS-CoV-2, has resulted in over 6 million reported deaths worldwide being one of the biggest challenges the world faces…”
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Cerebral venous sinus thrombosis as a consequence of shunt hyperdrainage: a proposal of the pathophysiological mechanism and case report
Published in Child's nervous system (2022)“…Background and aim Shunt dysfunction is a common event, especially in children who have this intervention performed early in life. The consequences of chronic…”
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Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate
Published in Scientific reports (22-06-2022)“…Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The…”
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The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif
Published in Biochemical journal (15-06-2012)“…Dengue is the major arthropod-borne human viral disease, for which no vaccine or specific treatment is available. We used NMR, zeta potential measurements and…”
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An Investigation into the Physical Mechanisms of Leak Noise Propagation in Buried Plastic Water Pipes: A Wave Dynamic Stiffness Approach
Published in Acoustics (Basel, Switzerland) (01-02-2024)“…In buried plastic water pipes, the predominantly fluid-borne wave is of particular interest, as it plays a key role in the propagation of leak noise…”
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From combinatorial peptide selection to drug prototype (I): Targeting the vascular endothelial growth factor receptor pathway
Published in Proceedings of the National Academy of Sciences - PNAS (16-03-2010)“…Inhibition of blood vessel formation is a viable therapeutic approach in angiogenesis-dependent diseases. We previously used a combinatorial screening on…”
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Coping with suboptimal water temperature: modifications in blood parameters, body composition, and postingestive-driven diet selection in Nile tilapia fed two vegetable oil blends
Published in Animal (Cambridge, England) (01-02-2021)“…The world tilapia production faces seasonal variations. However, very few nutritional studies have addressed suboptimal temperature. We evaluated the effect of…”
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Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis
Published in The Journal of immunology (1950) (15-05-2012)“…Intracellular pattern recognition receptors such as the nucleotide-binding oligomerization domain (NOD)-like receptors family members are key for innate immune…”
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A Cross-Reactive Human Single-Chain Antibody for Detection of Major Fish Allergens, Parvalbumins, and Identification of a Major IgE-Binding Epitope
Published in PloS one (18-11-2015)“…Fish allergy is associated with moderate to severe IgE-mediated reactions to the calcium binding parvalbumins present in fish muscle. Allergy to multiple fish…”
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Identification of regions involved in substrate binding and dimer stabilization within the central domains of yeast Hsp40 Sis1
Published in PloS one (05-12-2012)“…Protein folding, refolding and degradation are essential for cellular life and are regulated by protein homeostatic processes such those that involve the…”
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Dissection of the Water Cavity of Yeast Thioredoxin 1: The Effect of a Hydrophobic Residue in the Cavity
Published in Biochemistry (Easton) (21-04-2015)“…The water cavity of yeast thioredoxin 1 (yTrx1) is an ancestral, conserved structural element that is poorly understood. We recently demonstrated that the…”
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NMR assignment of free 1H, 15N and 13C-Grb2-SH2 domain
Published in Biomolecular NMR assignments (01-10-2019)“…Growth factor receptor-bound protein 2 (Grb2) is an adaptor protein composed of three domains, an N-terminal SH3 (nSH3), SH2 and a C-terminal SH3 (cSH3)…”
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A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11
Published in PloS one (20-10-2008)“…Interleukin-11 (IL-11) is a pleiotropic cytokine approved by the FDA against chemotherapy-induced thrombocytopenia. From a combinatorial selection in a cancer…”
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Structure-Function Relationship of the Disintegrin Family: Sequence Signature and Integrin Interaction
Published in Frontiers in molecular biosciences (03-12-2021)“…Disintegrins are small cysteine-rich proteins found in a variety of snake venom. These proteins selectively modulate integrin function, heterodimeric receptors…”
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