Search Results - "Almeida, I."
-
1
Long non-coding RNAs and cancer: a new frontier of translational research?
Published in Oncogene (25-10-2012)“…Tiling array and novel sequencing technologies have made available the transcription profile of the entire human genome. However, the extent of transcription…”
Get full text
Journal Article -
2
Lipids: biomarkers of healthy aging
Published in Biogerontology (Dordrecht) (01-06-2021)“…Life expectancy, and longevity have been increasing in recent years. However, this is, in most cases, accompanied by age-related diseases. Thus, it became…”
Get full text
Journal Article -
3
Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview
Published in Journal of inherited metabolic disease (01-02-2006)“…Summary Hyperhomocysteinaemia has been regarded as a new modifiable risk factor for atherosclerosis and vascular disease. Homocysteine is a branch‐point…”
Get full text
Journal Article -
4
Social-pair judgment bias testing in slow-growing broiler chickens raised in low- or high-complexity environments
Published in Scientific reports (09-06-2023)“…Impacts of environmental complexity on affective states in slow-growing broiler chickens ( Gallus gallus domesticus ) are unknown. Chickens’ performance in…”
Get full text
Journal Article -
5
Environmental determinants of radiolarian assemblages in the western Pacific since the last deglaciation
Published in Paleoceanography (01-08-2017)“…Radiolarians are a very diverse microzooplanktonic group, often distributed in regionally restricted assemblages and responding to specific environmental…”
Get full text
Journal Article -
6
Hydrographic control on carbon isotope fractionation in coccolithophores in the North Atlantic during the Mid-Pleistocene
Published in Quaternary science reviews (01-06-2023)“…The carbon isotopic fractionation during photosynthesis (Ɛp) from sedimentary alkenone biomarkers produced by coccolithophores is a widely used proxy for…”
Get full text
Journal Article -
7
Quantitative reconstruction of primary productivity in low latitudes during the last glacial maximum and the mid-to-late Holocene from a global Florisphaera profunda calibration dataset
Published in Quaternary science reviews (01-02-2019)“…Ocean net primary productivity (Npp) is a key component of the marine carbon cycle. Multi-model Npp projections based on a few decades of satellite data show…”
Get full text
Journal Article -
8
Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review
Published in Journal of inherited metabolic disease (01-04-2008)“…Summary Valproic acid (VPA; 2- n -propylpentanoic acid) is widely used as a major drug in the treatment of epilepsy and in the control of several types of…”
Get full text
Journal Article Conference Proceeding -
9
Bacterial cellulose membranes as drug delivery systems: An in vivo skin compatibility study
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2014)“…Bacterial cellulose (BC) is a highly pure form of cellulose, produced in the form of a swollen membrane by several bacteria that demonstrated to be able to…”
Get full text
Journal Article -
10
Impact of suborbital climate changes in the North Atlantic on ice sheet dynamics at the Mid-Pleistocene Transition
Published in Paleoceanography (01-09-2012)“…Early and Mid‐Pleistocene climate, ocean hydrography and ice sheet dynamics have been reconstructed using a high‐resolution data set (planktonic and…”
Get full text
Journal Article -
11
Tropically-driven climate shifts in southwestern Europe during MIS 19, a low eccentricity interglacial
Published in Earth and planetary science letters (01-08-2016)“…The relative roles of high- versus low-latitude forcing of millennial-scale climate variability are still not well understood. Here we present…”
Get full text
Journal Article -
12
Recent temperature trends in the South Central Andes reconstructed from sedimentary chrysophyte stomatocysts in Laguna Escondida (1742ma.s.l., 38°28S, Chile)
Published in Global and planetary change (01-02-2016)“…In this study we present a quantitative, high resolution reconstruction of past austral winter length in the Chilean Andes at 38°S from AD 1920 to 2009. For…”
Get full text
Journal Article -
13
Chrysophyte cyst-inferred variability of warm season lake water chemistry and climate in northern Poland: training set and downcore reconstruction
Published in Journal of paleolimnology (01-01-2015)“…Chrysophyte cyst assemblages from sediment trap and surface sediment samples of 50 lakes in northern Poland were related to environmental variables using…”
Get full text
Journal Article -
14
Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2012)“…Background & Aims MicroRNAs (miRNAs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse…”
Get full text
Journal Article -
15
Photostabilization strategies of photosensitive drugs
Published in International journal of pharmaceutics (25-04-2018)“…[Display omitted] Several active compounds are sensitive to light, especially to the ultraviolet radiation (UV-R) leading to their degradation or modification,…”
Get full text
Journal Article -
16
Dynamic flux of microvesicles modulate parasite–host cell interaction of Trypanosoma cruzi in eukaryotic cells
Published in Cellular microbiology (01-04-2017)“…Extracellular vesicles released from pathogens may alter host cell functions. We previously demonstrated the involvement of host cell‐derived microvesicles…”
Get full text
Journal Article -
17
Dendritic Cell-derived Extracellular Vesicles mediate Mesenchymal Stem/Stromal Cell recruitment
Published in Scientific reports (10-05-2017)“…Orchestration of bone repair processes requires crosstalk between different cell populations, including immune cells and mesenchymal stem/stromal cells (MSC)…”
Get full text
Journal Article -
18
Oxygen control in bioreactor drives high yield production of functional hiPSC-like hepatocytes for advanced liver disease modelling
Published in Scientific reports (19-10-2024)“…Hepatocytes-like cells (HLC) derived from human induced pluripotent stem cells show great promise for cell-based liver therapies and disease modelling…”
Get full text
Journal Article -
19
A chrysophyte-based quantitative reconstruction of winter severity from varved lake sediments in NE Poland during the past millennium and its relationship to natural climate variability
Published in Quaternary science reviews (15-08-2015)“…Chrysophyte cysts are recognized as powerful proxies of cold-season temperatures. In this paper we use the relationship between chrysophyte assemblages and the…”
Get full text
Journal Article -
20
How Inflammation Impinges on NAFLD: A Role for Kupffer Cells
Published in BioMed research international (01-01-2015)“…Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently…”
Get full text
Journal Article