Search Results - "Almeida, Ayla das Chagas"
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Functionalized 1,2,3-triazolium salts as potential agents against visceral leishmaniasis
Published in Parasitology research (1987) (01-05-2022)“…Visceral leishmaniasis (VL) is the most severe clinical form of leishmaniasis, being fatal if untreated. In search of a more effective treatment for VL, one of…”
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Imidazo[1,2‑a]pyrimidine as a New Antileishmanial Pharmacophore against Leishmania amazonensis Promastigotes and Amastigotes
Published in ACS omega (31-10-2023)“…Leishmania poses a substantial threat to the human population all over the globe because of its visceral and cutaneous spread engendered by all 20 species…”
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In Vitro Schistosomicidal Activity of the Alkaloid-Rich Fraction from Ruta graveolens L. (Rutaceae) and Its Characterization by UPLC-QTOF-MS
Published in Evidence-based complementary and alternative medicine (2019)“…Schistosomiasis is a neglected tropical disease that affects million people worldwide, mostly in developing countries. Ruta graveolens (Rutaceae) is a plant…”
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Prenylated flavonoid-enriched fraction from Maclura tinctoria shows biological activity against Staphylococcus aureus and protects Galleria mellonella larvae from bacterial infection
Published in BMC complementary and alternative medicine (29-07-2019)“…The Atlantic Forest biome extends along the entire Brazilian coast and is home to approximately 20,000 plant species, many of which are endemic; it is…”
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In vitro Assessment of Camphor Hydrazone Derivatives as an Agent Against Leishmania amazonensis
Published in Acta parasitologica (01-03-2020)“…Purpose Due to serious problems with the treatment of leishmaniasis all around the world, here is an urgent need in the search for new drugs that are more…”
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Novel functionalized 1,2,3-triazole derivatives exhibit antileishmanial activity, increase in total and mitochondrial-ROS and depolarization of mitochondrial membrane potential of Leishmania amazonensis
Published in Chemico-biological interactions (05-01-2020)“…1,2,3-triazolium salts are poorly understood regarding their antileishmanial activity. Hence, as an effort to identify novel chemical scaffolds as…”
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Aminoquinoline compounds: Effect of 7-chloro-4-quinolinylhydrazone derivatives against Leishmania amazonensis
Published in Experimental parasitology (01-12-2016)“…In this study, we have investigated the antileishmanial activity of ten 7-chloro-4-quinolinylhydrazone derivatives. Among the compounds tested, compounds 2a…”
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In Vitro Schistosomicidal Activity of the Alkaloid-Rich Fraction from Ruta graveolens L
Published in Evidence-based complementary and alternative medicine (30-11-2019)Get full text
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Antibacterial screening of plants from the Brazilian Atlantic Forest led to the identification of active compounds in Miconia latecrenata (DC.) Naudin
Published in Natural product research (04-08-2020)“…Antibiotic resistance is a serious global threat to public health. This has promoted the research for new drug targets, and the use of other approaches, such…”
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Antibacterial screening of plants from the Brazilian Atlantic Forest led to the identification of active compounds in Miconia latecrenata (DC.) Naudin
Published in Natural Product Research (17-12-2021)“…Antibiotic resistance is a serious global threat to public health. This has promoted the research for new drug targets, and the use of other approaches, such…”
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