Search Results - "Almeida, Anne C. G"

Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile by Baro, Barbara, Deroost, Katrien, Raiol, Tainá, Brito, Marcelo, Almeida, Anne C G, de Menezes-Neto, Armando, Figueiredo, Erick F G, Alencar, Aline, Leitão, Rodrigo, Val, Fernando, Monteiro, Wuelton, Oliveira, Anna, Armengol, Maria Del Pilar, Fernández-Becerra, Carmen, Lacerda, Marcus V, Del Portillo, Hernando A

“…The presence of P. vivax in the bone marrow was first noticed in the late 19th century [2], and examinations of sternal bone marrow aspirates were performed as…”
Get full text

CYP2D6 activity and the risk of recurrence of Plasmodium vivax malaria in the Brazilian Amazon: a prospective cohort study by Brasil, Larissa W, Rodrigues-Soares, Fernanda, Santoro, Ana B, Almeida, Anne C G, Kühn, Andrea, Ramasawmy, Rajendranath, Lacerda, Marcus V G, Monteiro, Wuelton M, Suarez-Kurtz, Guilherme

“…CYP2D6 pathway mediates the activation of primaquine into active metabolite(s) in hepatocytes. CYP2D6 is highly polymorphic, encoding CYP2D6 isoforms with…”
Get full text

Chemistry and Pharmacology of Bergenin or Its Derivatives: A Promising Molecule by Salimo, Zeca M, Yakubu, Michael N, da Silva, Emanuelle L, de Almeida, Anne C G, Chaves, Yury O, Costa, Emmanoel V, da Silva, Felipe M A, Tavares, Josean F, Monteiro, Wuelton M, de Melo, Gisely C, Koolen, Hector H F

“…Bergenin is a glycosidic derivative of trihydroxybenzoic acid that was discovered in 1880 by Garreau and Machelart from the rhizomes of the medicinal plant…”
Get full text

High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon by Almeida, Anne C G, Kuehn, Andrea, Castro, Arthur J M, Vitor-Silva, Sheila, Figueiredo, Erick F G, Brasil, Larissa W, Brito, Marcelo A M, Sampaio, Vanderson S, Bassat, Quique, Felger, Ingrid, Tadei, Wanderli P, Monteiro, Wuelton M, Mueller, Ivo, Lacerda, Marcus V G

“…Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts…”
Get full text

G6PD deficiency in Latin America: systematic review on prevalence and variants by Monteiro, Wuelton M, Val, Fernando F. A, Siqueira, André M, Franca, Gabriel P, Sampaio, Vanderson S, Melo, Gisely C, Almeida, Anne C. G, Brito, Marcelo A. M, Peixoto, Henry M, Fuller, Douglas, Bassat, Quique, Romero, Gustavo A. S, Oliveira, Maria Regina F, Larcerda, Marcus Vinícius G

“…Plasmodium vivax radical cure requires the use of primaquine (PQ), a drug that induces haemolysis in glucose-6-phosphate dehydrogenase deficient (G6PDd)…”
Get full text

Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections by Brito, Marcelo A M, Baro, Bàrbara, Raiol, Tainá C, Ayllon-Hermida, Alberto, Safe, Izabella P, Deroost, Katrien, Figueiredo, Erick F G, Costa, Allyson G, Armengol, Maria del P, Sumoy, Lauro, Almeida, Anne C G, Hounkpe, Bidossessi W, De Paula, Erich V, Fernandez-Becerra, Cármen, Monteiro, Wuelton M, del Portillo, Hernando A, Lacerda, Marcus V G

“…Abstract Background The presence of Plasmodium vivax malaria parasites in the human bone marrow (BM) is still controversial. However, recent data from a…”
Get full text

Host metabolomic responses in recurrent P. vivax malaria by Yakubu, Michael N., Mwangi, Victor I., Netto, Rebeca L. A., Alecrim, Maria G. C., Alves, Jessica R. S., Almeida, Anne C. G., Santos, Gabriel F., Lima, Gesiane S., Machado, Lucas S., Koolen, Hector H. F., Guimarães, Tiago P., Chaves, Andrea R., Vaz, Boniek G., Monteiro, Wuelton M., Costa, Fabio T. M., Lacerda, Marcus V. G., Gardinassi, Luiz G., de Melo, Gisely C.

“…Malaria is the leading parasitic disease worldwide, with P. vivax being a major challenge for its control. Several studies have indicated metabolomics as a…”
Get full text

Influence of CYP2C8 , CYP3A4 , and CYP3A5 Host Genotypes on Early Recurrence of Plasmodium vivax by Almeida, Anne C G, Puça, Maria C B, Figueiredo, Erick F G, Barbosa, Laila R, Salazar, Yanka E A R, Silva, Emanuelle L, Brito, Marcelo A M, Siqueira, André M, Vieira, José L F, Lacerda, Marcus V G, Monteiro, Wuelton M, Melo, Gisely C

“…Cytochrome P450 (CYP) enzymes are involved in the biotransformation of chloroquine (CQ), but the role of the different profiles of metabolism of this drug in…”
Get full text

Association of CYP2C19, CYP2D6 and CYP3A4 Genetic Variants on Primaquine Hemolysis in G6PD-Deficient Patients by Macêdo, Marielle M, Almeida, Anne C G, Silva, Gabrielly S, Oliveira, Amanda C, Mwangi, Victor I, Shuan, Ana C, Barbosa, Laila R A, Rodrigues-Soares, Fernanda, Melo, Gisely C

“…In the Amazon, the treatment for is chloroquine plus primaquine. However, this regimen is limited due to the risk of acute hemolytic anemia in…”
Get full text

TOLLIP gene variant is associated with Plasmodium vivax malaria in the Brazilian Amazon by Brasil, Larissa W, Barbosa, Laila R A, de Araujo, Felipe J, da Costa, Allyson G, da Silva, Luan D O, Pinheiro, Suzana K, de Almeida, Anne C G, Kuhn, Andrea, Vitor-Silva, Sheila, de Melo, Gisely C, Monteiro, Wuelton M, de Lacerda, Marcus V G, Ramasawmy, Rajendranath

“…Toll-interacting protein is a negative regulator in the TLR signaling cascade, particularly by impeding the TLR2 and, TLR4 pathway. Recently, TOLLIP was shown…”
Get full text

An Ultra-Sensitive Technique: Using Pv -mtCOX1 qPCR to Detect Early Recurrences of Plasmodium vivax in Patients in the Brazilian Amazon by Barbosa, Laila R A, da Silva, Emanuelle L, de Almeida, Anne C G, Salazar, Yanka E A R, Siqueira, André M, Alecrim, Maria das Graças Costa, Vieira, José Luiz Fernandes, Bassat, Quique, de Lacerda, Marcus V G, Monteiro, Wuelton M, Melo, Gisely C

“…Early recurrence of is a challenge for malaria control in the field, particularly because this species is associated with lower parasitemia, which hinders…”
Get full text

Pharmacokinetics of chloroquine in patients with malaria by P. vivax from the Western Brazilian Amazon basin by Melo, Marly M., Costa, Monica R.F., Filho, Franklin S.Santana, Brito-Sousa, José Diego, Almeida, Anne C.G., Monteiro, Wuelton M., Melo, Gisely C., Vieira, José Luiz Fernandes, Alecrim, Maria das Graças Costa

“…The western Amazon basin is an important endemic area for malaria by P. vivax. In recent years, several reports showed the treatment failure with chloroquine,…”
Get full text

Systems biology of disease tolerance to malaria by Toméi, Maria Cm, Silva, Nágila I, Almeida, Anne Cg, Gardinassi, Luiz G

Get full text

Association of ICYP2C19, CYP2D6/I and ICYP3A4/I Genetic Variants on Primaquine Hemolysis in G6PD-Deficient Patients by Macêdo, Marielle M, Almeida, Anne C. G, Silva, Gabrielly S, Oliveira, Amanda C, Mwangi, Victor I, Shuan, Ana C, Barbosa, Laila R. A, Rodrigues-Soares, Fernanda, Melo, Gisely C

“…In the Amazon, the treatment for Plasmodium vivax is chloroquine plus primaquine. However, this regimen is limited due to the risk of acute hemolytic anemia in…”
Get full text

Influence of CYP2D6, CYP3A4 and CYP2C19 Genotypes on Recurrence of Plasmodium vivax by Cardoso, Jaiana L. M., Salazar, Yanka E. A. R., Almeida, Anne C. G., Barbosa, Laila R. A., Silva, Emanuelle L., Rodrigues, Maria Gabriela Almeida, Rodrigues-Soares, Fernanda, Sampaio, Vanderson S., Siqueira, André M., Lacerda, Marcus V. G., Monteiro, Wuelton M., Melo, Gisely C.

Get full text