Search Results - "Almawash, Saud"
-
1
Solid lipid nanoparticles, an effective carrier for classical antifungal drugs
Published in Saudi pharmaceutical journal (01-07-2023)“…Solid-lipid nanoparticles (SLNs) are an innovative group of nanosystems used to deliver medicine to their respective targets with better efficiency and…”
Get full text
Journal Article -
2
Self-ratiometric fluorescence approach based on plant extract-assisted synthesized silver nanoparticles for the determination of vanillin
Published in Mikrochimica acta (1966) (01-01-2024)“…The current study designed and applied a novel self-ratiometric fluorescent nanosensor composed of green-synthesized silver nanoparticles (Ag-NPs) to determine…”
Get full text
Journal Article -
3
Current and Future Prospective of Injectable Hydrogels-Design Challenges and Limitations
Published in Pharmaceuticals (Basel, Switzerland) (18-03-2022)“…Injectable hydrogels (IHs) are smart biomaterials and are the most widely investigated and versatile technologies, which can be either implanted or inserted…”
Get full text
Journal Article -
4
Coadministration of Polymeric Conjugates of Docetaxel and Cyclopamine Synergistically Inhibits Orthotopic Pancreatic Cancer Growth and Metastasis
Published in Pharmaceutical research (01-01-2018)“…Purpose The aim of this study was to determine whether co-administration of hedgehog (Hh) pathway inhibitor cyclopamine (CYP) and microtubule stabilizer…”
Get full text
Journal Article -
5
Polymerized β-Cyclodextrin-Based Injectable Hydrogel for Sustained Release of 5-Fluorouracil/Methotrexate Mixture in Breast Cancer Management: In Vitro and In Vivo Analytical Validations
Published in Pharmaceutics (08-04-2022)“…An inclusion complexation, between polymerized β-cyclodextrin and cholesterol end-capping branched polyethylene glycol, was utilized for constructing a…”
Get full text
Journal Article -
6
Bioavailability and Antidiabetic Activity of Gliclazide-Loaded Cubosomal Nanoparticles
Published in Pharmaceuticals (Basel, Switzerland) (09-08-2021)“…In this study, gliclazide-loaded cubosomal particles were prepared for improving the oral bioavailability and antidiabetic activity of gliclazide. Four…”
Get full text
Journal Article -
7
Mechanistic insights into the role of plant polyphenols and their nano-formulations in the management of depression
Published in Frontiers in pharmacology (07-11-2022)“…Depression is a condition characterized by low mood and an aversion to activity, that causes behavioral problems, poor quality of life and limits daily life…”
Get full text
Journal Article -
8
Ischemic Stroke and Autophagy: The Roles of Long Non-Coding RNAs
Published in Current neuropharmacology (2024)“…Ischemic stroke is a significant cause of morbidity and mortality worldwide. Autophagy, a process of intracellular degradation, has been shown to play a…”
Get full text
Journal Article -
9
Antioxidant, LC-MS Analysis, and Cholinesterase Inhibitory Potentials of Phoenix dactylifera Cultivar Khudari: An In Vitro Enzyme Kinetics and In Silico Study
Published in Biomolecules (Basel, Switzerland) (30-09-2023)“…We evaluated the therapeutic potentials of Khudari fruit pulp, a functional food and cultivar of Phoenix dactylifera, against neurological disorders. Our…”
Get full text
Journal Article -
10
Dual Delivery of Fluticasone Propionate and Levocetirizine Dihydrochloride for the Management of Atopic Dermatitis Using a Microemulsion-Based Topical Gel
Published in ACS omega (08-03-2022)“…The current study investigates the potential for topical delivery of a fluticasone propionate (FP) and levocetirizine dihydrochloride (CTZ)-loaded…”
Get full text
Journal Article -
11
Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation
Published in Frontiers in pharmacology (07-02-2023)“…The purpose of this study was to assess the parameters of doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then…”
Get full text
Journal Article -
12
Injectable Hydrogels Based on Cyclodextrin/Cholesterol Inclusion Complexation and Loaded with 5-Fluorouracil/Methotrexate for Breast Cancer Treatment
Published in Gels (01-04-2023)“…Breast cancer is the second most common cancer in women worldwide. Long-term treatment with conventional chemotherapy may result in severe systemic side…”
Get full text
Journal Article -
13
Preparation, Characterization, and Evaluation of Physcion Nanoparticles for Enhanced Oral Bioavailability: An Attempt to Improve Its Antioxidant and Anticancer Potential
Published in ACS omega (19-09-2023)“…This study aims to enhance the dissolution rate of a poorly water-soluble drug physcion by producing its nanoparticles (NPs) using an antisolvent precipitation…”
Get full text
Journal Article -
14
Fabrication and Evaluation of W/O Emulsion Loaded with Linum usitatissimum Seeds Extract for Anti-Leishmaniasis Efficacy
Published in Antibiotics (Basel) (23-03-2022)“…Leishmaniasis, remains a serious health problem in many developing countries with thousands of new cases recorded annually. Novel therapies are required as…”
Get full text
Journal Article -
15
EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer
Published in Molecular pharmaceutics (05-09-2017)“…Gemcitabine (GEM), a first-line chemotherapy for pancreatic cancer undergoes rapid metabolism and develops chemoresistance after repeated administration. We…”
Get full text
Journal Article -
16
Nanomedicine as a potential novel therapeutic approach against the dengue virus
Published in Nanomedicine (London, England) (01-09-2023)“…Dengue is an arbovirus infection which is transmitted by mosquitoes. Its prompt detection and effective treatment is a global health challenge. Various…”
Get full text
Journal Article -
17
Topical non-aqueous nanoemulsion of Alpinia galanga extract for effective treatment in psoriasis: In vitro and in vivo evaluation
Published in International journal of pharmaceutics (25-08-2022)“…[Display omitted] Non-aqueous nanoemulsion (NANE) of Alpinia galanga extract (AGE) was prepared using Palmester 3595 (MCT oil) as oil phase, Cremophor RH…”
Get full text
Journal Article -
18
The use of micelles to deliver potential hedgehog pathway inhibitor for the treatment of liver fibrosis
Published in Theranostics (01-01-2019)“…Hedgehog (Hh) pathway plays an essential role in liver fibrosis by promoting the proliferation of hepatic stellate cells (HSCs) by enhancing their metabolism…”
Get full text
Journal Article -
19
Accelerated Wound Healing Potential of Nisin in Streptozotocin Induced Diabetes Mellitus in Wistar Rats
Published in International journal of peptide research and therapeutics (22-08-2022)“…About twenty percent of diabetic patients develop diabetic wounds and diabetic foot gradually resulting in severe infections and lower limb complications…”
Get full text
Journal Article -
20
Chitosan-based nanoconjugate for safe and effective delivery of docetaxel to cancer cells: An explorative study
Published in Journal of drug delivery science and technology (01-08-2021)“…The objective of the study was to develop novel chitosan-based nanoconjugate intended for intravenous drug delivery to enhance the therapeutic efficacy of the…”
Get full text
Journal Article