Search Results - "Alm, JJ"
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Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?
Published in Stem cells (Dayton, Ohio) (01-09-2014)“…We have recently reported that therapeutic mesenchymal stromal cells (MSCs) have low engraftment and trigger the instant blood mediated inflammatory reaction…”
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Mucosal IgA protects against BQ.1 and BQ.1.1 infection
Published in The Lancet infectious diseases (01-08-2023)“…While SARS-CoV-2 vaccines and previous infections still safeguard against severe and fatal COVID-19, protection against infection has waned substantially after…”
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Mucosal and Serum Antibodies 3 Weeks after Symptomatic BA.2.86 Infection
Published in The New England journal of medicine (26-10-2023)“…Infection with the BA.2.86 subvariant in a vaccinated and previously infected person yielded a strong induction of mucosal IgA binding to the wild-type and…”
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Biomarkers in WNT1 and PLS3 Osteoporosis: Altered Concentrations of DKK1 and FGF23
Published in Journal of bone and mineral research (01-05-2020)“…ABSTRACT Recent advancements in genetic research have uncovered new forms of monogenic osteoporosis, expanding our understanding of the molecular pathways…”
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Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes bone length, regulates cortical and trabecular bone mass, and maintains growth plate architecture and width in a sex- and site-specific manner in mice
Published in Bone (New York, N.Y.) (01-11-2024)“…Tartrate-resistant acid phosphatase (TRAP) serum levels reflect osteoclast number, bone remodeling activity, and fracture risk. Deletion or loss of function of…”
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New Insights Into Monogenic Causes of Osteoporosis
Published in Frontiers in endocrinology (Lausanne) (2019)“…Osteoporosis, characterized by deteriorated bone microarchitecture and low bone mineral density, is a chronic skeletal disease with high worldwide prevalence…”
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Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers
Published in Nature communications (2023)“…Vaccination offers protection against severe COVID-19 caused by SARS-CoV-2 omicron but is less effective against infection. Characteristics such as serum…”
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Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans
Published in EMBO molecular medicine (2024)“…Psoriatic arthritis mutilans (PAM) is the rarest and most severe form of psoriatic arthritis, characterized by erosions of the small joints and osteolysis…”
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Novel RPL13 Variants and Variable Clinical Expressivity in a Human Ribosomopathy With Spondyloepimetaphyseal Dysplasia
Published in Journal of bone and mineral research (01-02-2021)“…ABSTRACT Spondyloepimetaphyseal dysplasias (SEMDs) are a heterogeneous group of disorders with variable growth failure and skeletal impairments affecting the…”
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Do ABO blood group antigens hamper the therapeutic efficacy of mesenchymal stromal cells?
Published in PloS one (13-01-2014)“…Investigation into predictors for treatment outcome is essential to improve the clinical efficacy of therapeutic multipotent mesenchymal stromal cells (MSCs)…”
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Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis
Published in eLife (08-11-2021)“…Reliable, robust, large-scale molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for monitoring the ongoing…”
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Novel fibronectin mutations and expansion of the phenotype in spondylometaphyseal dysplasia with “corner fractures”
Published in Bone (New York, N.Y.) (01-04-2019)“…Heterozygous pathogenic variants in the FN1 gene, encoding fibronectin (FN), have recently been shown to be associated with a skeletal disorder in some…”
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Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination
Published in Stem cells translational medicine (01-10-2017)“…Vascular changes, including blood brain barrier destabilization, are common pathological features in multiple sclerosis (MS) lesions. Blood vessels within…”
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Prevalence of SARS-CoV-2 infections among Swedish healthcare workers on duty in December 2023
Published in The Lancet regional health. Europe (01-03-2024)Get full text
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Point prevalence of SARS-CoV-2 infection among healthcare workers in March and June 2023 in Sweden
Published in The Lancet regional health. Europe (01-10-2023)Get full text
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Type 1 Diabetes Mellitus Donor Mesenchymal Stromal Cells Exhibit Comparable Potency to Healthy Controls In Vitro
Published in Stem cells translational medicine (01-11-2016)“…The authors used gene array in combination with functional in vitro assays to study mesenchymal stromal cells (MSCs) from donors with type 1 diabetes (T1D) and…”
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Low PLS3 Expression Impairs Osteoblast Differentiation of Pediatric MSCs in vitro
Published in JOURNAL OF BONE AND MINERAL RESEARCH (2019)Get full text
Conference Proceeding -
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Transient 100 nM dexamethasone treatment reduces inter- and intraindividual variations in osteoblastic differentiation of bone marrow-derived human mesenchymal stem cells
Published in Tissue engineering. Part C, Methods (01-09-2012)“…The development of in vitro culturing techniques for osteoblastic differentiation of human mesenchymal stem cells (hMSC) is important for cell biology research…”
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Immunohistochemical characterization of mesenchymal perivascular stem/stromal cells in multiple sclerosis and healthy brain tissue
Published in MULTIPLE SCLEROSIS JOURNAL (2016)Get full text
Conference Proceeding