Search Results - "Allwood, J. William"
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Iron and zinc bioavailability in common bean (Phaseolus vulgaris) is dependent on chemical composition and cooking method
Published in Food chemistry (01-09-2022)“…•Fe/Zn bioavailability in common bean is dependent on genotype and cooking method.•Genotypes used in this study exhibited little variation in phytic acid…”
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AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome
Published in The journal of clinical endocrinology and metabolism (01-09-2017)“…Abstract Context Polycystic ovary syndrome (PCOS) is a prevalent metabolic disorder occurring in up to 10% of women of reproductive age. PCOS is associated…”
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Fingerprinting food: current technologies for the detection of food adulteration and contamination
Published in Chemical Society reviews (01-01-2012)“…Major food adulteration and contamination events seem to occur with some regularity, such as the widely publicised adulteration of milk products with melamine…”
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Extraction, Enrichment, and LC-MSn-Based Characterization of Phlorotannins and Related Phenolics from the Brown Seaweed, Ascophyllum nodosum
Published in Marine drugs (27-08-2020)“…Phenolic components from the edible brown seaweed, Ascophyllum nodosum, have been associated with considerable antioxidant activity but also bioactivities…”
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pH plays a role in the mode of action of trimethoprim on Escherichia coli
Published in PloS one (13-07-2018)“…Metabolomics-based approaches were applied to understand interactions of trimethoprim with Escherichia coli K-12 at sub-minimum inhibitory concentrations…”
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Metabolic fingerprinting as a diagnostic tool
Published in Pharmacogenomics (01-09-2007)“…Within the framework of systems biology, functional analyses at all 'omic levels have seen an intense level of activity during the first decade of the…”
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Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract
Published in PloS one (22-02-2021)“…In this work, a new magnetic ligand fishing probe for discovery of DPP-IV inhibitory ligands was developed and it was tested as a proof of concept on the fruit…”
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8
Light Regulation of Chlorophyll and Glycoalkaloid Biosynthesis During Tuber Greening of Potato S. tuberosum
Published in Frontiers in plant science (30-06-2020)“…Potato, , is one of the most important global crops, but has high levels of waste due to tuber greening under light, which is associated with the accumulation…”
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Metabolic acclimation to hypoxia revealed by metabolite gradients in melon fruit
Published in Journal of plant physiology (15-02-2010)“…A metabolomics approach using 1H NMR and GC–MS profiling of primary metabolites and quantification of adenine nucleotides with luciferin bioluminescence was…”
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Ex vivo fecal fermentation of human ileal fluid collected after raspberry consumption modifies (poly)phenolics and modulates genoprotective effects in colonic epithelial cells
Published in Redox biology (01-04-2021)“…Diets rich in fruit and vegetables are associated with a decreased incidence of colorectal cancer (CRC) due, in part, to the bioactive (poly)phenolic…”
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Assessing the Intestinal Permeability and Anti-Inflammatory Potential of Sesquiterpene Lactones from Chicory
Published in Nutrients (19-11-2020)“…L. has recently gained major attention due to large quantities of health-promoting compounds in its roots, such as inulin and sesquiterpene lactones (SLs)…”
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Metabolomics in melon: A new opportunity for aroma analysis
Published in Phytochemistry (Oxford) (01-03-2014)“…Melon fruit value is highly influenced by aroma. A simple and robust method of trapping volatile organic compounds combined with detection via thermal…”
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Profiling of spatial metabolite distributions in wheat leaves under normal and nitrate limiting conditions
Published in Phytochemistry (Oxford) (01-07-2015)“…•Nitrogen and carbon assimilation interaction is essential in leaf metabolism.•Along the developing wheat leaf there is a switch from hetero- to…”
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14
Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy
Published in Molecular bioSystems (01-02-2015)“…Energy depletion has been highlighted as an important contributor to the pathology of hypertrophic cardiomyopathy (HCM), a common inherited cardiac disease…”
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Metabolomic approaches reveal that cell wall modifications play a major role in ethylene‐mediated resistance against Botrytis cinerea
Published in The Plant journal : for cell and molecular biology (01-09-2011)“…Summary In Arabidopsis, resistance to the necrotrophic fungus Botrytis cinerea is conferred by ethylene via poorly understood mechanisms. Metabolomic…”
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Selective induction and subcellular distribution of ACONITASE 3 reveal the importance of cytosolic citrate metabolism during lipid mobilization in Arabidopsis
Published in Biochemical journal (15-10-2014)“…Arabidopsis thaliana has three genes that encode distinct aconitases (ACO), but little is known about the function of each isoenzyme during plant development…”
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Dual metabolomics: A novel approach to understanding plant–pathogen interactions
Published in Phytochemistry (Oxford) (01-04-2010)“…A co-culture method is proposed for the dual metabolomic profiling of both Arabidopsis and bacterial pathogens which will facilitate the modelling of the…”
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18
Central Metabolism Is Tuned to the Availability of Oxygen in Developing Melon Fruit
Published in Frontiers in plant science (15-05-2019)“…Respiration of bulky plant organs such as fleshy fruits depends on oxygen (O ) availability and often decreases with O concentration to avoid anoxia, but the…”
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Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory non‐polar metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea
Published in The Plant journal : for cell and molecular biology (01-05-2006)“…Summary Metabolomic approaches were used to elucidate some key metabolite changes occurring during interactions of Magnaporthe grisea– the cause of rice blast…”
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A Transcript and Metabolite Atlas of Blackcurrant Fruit Development Highlights Hormonal Regulation and Reveals the Role of Key Transcription Factors
Published in Frontiers in plant science (24-08-2018)“…Blackcurrant fruit collected at six stages of development were assessed for changes in gene expression using custom whole transcriptome microarrays and for…”
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