Search Results - "Allu, Prasanna K R"
-
1
PCR-based segregation of one hybrid variety of Labeo rohita and Catla catla from their wild-types
Published in Aquaculture international (01-04-2014)“…High consumer preference together with its polyculture potential has undoubtedly driven Rohu (Labeo rohita) and Catla (Catla catla) to top the list of the most…”
Get full text
Journal Article -
2
Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders
Published in Diabetes (New York, N.Y.) (01-03-2022)“…Pancreastatin (PST), a chromogranin A-derived potent physiological dysglycemic peptide, regulates glucose/insulin homeostasis. We have identified a…”
Get full text
Journal Article -
3
Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo
Published in Scientific reports (01-02-2018)“…The type 2 diabetic phenotype results from mixed effects of insulin deficiency and insulin resistance, but the relative contributions of these two distinct…”
Get full text
Journal Article -
4
A common genetic variant of the chromogranin A-derived peptide catestatin is associated with atherogenesis and hypertension in a Japanese population
Published in ENDOCRINE JOURNAL (01-09-2015)“…[Abstract] Chromogranin A (CHGA) is a major protein in the secretory granules of chromaffin cells. CHGA also gives rise to cardiovascular/metabolism regulatory…”
Get full text
Journal Article -
5
Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor
Published in Journal of cell science (01-05-2012)“…Catestatin (CST), a chromogranin-A-derived peptide, is a potent endogenous inhibitor of the neuronal nicotinic acetylcholine receptor (nAChR). It exerts an…”
Get full text
Journal Article -
6
A common genetic variant of the chromogranin A-derived peptide catestatin is associated with atherogenesis and hypertension in a Japanese population
Published in Endocrine Journal (2015)“…Chromogranin A (CHGA) is a major protein in the secretory granules of chromaffin cells. CHGA also gives rise to cardiovascular/metabolism regulatory peptides,…”
Get full text
Journal Article -
7
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function
Published in Circulation research (04-12-2020)“…RATIONALE:Cardiac pacemaker cells (PCs) in the sinoatrial node (SAN) have a distinct gene expression program that allows them to fire automatically and…”
Get full text
Journal Article -
8
Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19
Published in Medical hypotheses (01-11-2020)“…To address urgent need for strategies to limit mortality from coronavirus disease 2019 (COVID-19), this review describes experimental, clinical and…”
Get full text
Journal Article -
9
Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold
Published in The Journal of biological chemistry (01-01-2021)“…Nonshivering thermogenesis is essential for mammals to maintain body temperature. According to the canonical view, temperature is sensed by cutaneous…”
Get full text
Journal Article -
10
Catestatin Gly364Ser Variant Alters Systemic Blood Pressure and the Risk for Hypertension in Human Populations via Endothelial Nitric Oxide Pathway
Published in Hypertension (Dallas, Tex. 1979) (01-08-2016)“…Catestatin (CST), an endogenous antihypertensive/antiadrenergic peptide, is a novel regulator of cardiovascular physiology. Here, we report case–control…”
Get full text
Journal Article -
11
A haplotype variant of the human chromogranin A gene (CHGA) promoter increases CHGA expression and the risk for cardiometabolic disorders
Published in The Journal of biological chemistry (25-08-2017)“…The acidic glycoprotein chromogranin A (CHGA) is co-stored/co-secreted with catecholamines and crucial for secretory vesicle biogenesis in…”
Get full text
Journal Article -
12
FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation
Published in Molecular metabolism (Germany) (01-12-2023)“…Insulin acts on the liver via changes in gene expression to maintain glucose and lipid homeostasis. This study aimed to the Forkhead box protein K1 (FOXK1)…”
Get full text
Journal Article -
13
Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation
Published in The Journal of biological chemistry (14-02-2014)“…Pancreastatin (PST), a chromogranin A-derived peptide, is a potent physiological inhibitor of glucose-induced insulin secretion. PST also triggers…”
Get full text
Journal Article -
14
Functional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: allele-specific effects on metabolic traits
Published in The Journal of biological chemistry (21-12-2012)“…Catestatin (CST), a chromogranin A (CHGA)-derived peptide, is a potent inhibitor of catecholamine release from adrenal chromaffin cells and postganglionic…”
Get full text
Journal Article -
15
CATESTATIN GLY364SER VARIANT ALTERS SYSTEMIC BLOOD PRESSURE AND THE RISK FOR HYPERTENSION IN HUMAN POPULATIONS VIA ENDOTHELIAL NO PATHWAY
Published in Hypertension (Dallas, Tex. 1979) (20-06-2016)“…Catestatin (CST), an endogenous anti-hypertensive/anti-adrenergic peptide, is a novel regulator of cardiovascular physiology. Here, we report case-control…”
Get full text
Journal Article -
16
Molecular interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor
Published in Journal of cell science (01-06-2012)Get full text
Journal Article -
17
Molecular mechanism of interactions of the physiological anti-hypertensive peptide catestatin with the neuronal nicotinic acetylcholine receptor
Published in Journal of cell science (01-01-2012)“…Catestatin (CST), a chromogranin A-derived peptide, is a potent endogenous inhibitor of the neuronal nicotinic acetylcholine receptor (nAChR). It exerts…”
Get full text
Journal Article -
18
Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors 13 C-lactate and 13 C-pyruvate in kidney and liver
Published in Magnetic resonance in medicine (01-04-2017)“…The purpose of this study was to characterize tissue-specific alterations in metabolism of hyperpolarized (HP) gluconeogenic precursors C-lactate and…”
Get full text
Journal Article -
19
Detecting Metabolism of Gluconeogenic Precursors Lactate and Pyruvate in Kidney & Liver with Hyperpolarized 13 C MRI
Published in The FASEB journal (01-04-2016)“…Abstract only Objective The objective of this study was to apply new methods in hyperpolarized (HP) 13C magnetic resonance imaging (MRI) to characterize…”
Get full text
Journal Article -
20
Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors super(13)C-lactate and super(13)C-pyruvate in kidney and liver
Published in Magnetic resonance in medicine (01-04-2017)“…Purpose The purpose of this study was to characterize tissue-specific alterations in metabolism of hyperpolarized (HP) gluconeogenic precursors…”
Get full text
Journal Article