Search Results - "Allsopp, C. E. M"

Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria by Ruwende, C, Khoo, S. C, Snow, R. W, Yates, S. N. R, Kwiatkowski, D, Gupta, S, Warn, P, Allsopp, C. E. M, Gilbert, S. C, Peschu, N, Newbold, C. I, Greenwood, B. M, Marsh, K, Hill, A. V. S

“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common enzymopathy of humans, affects over 400 million people. The geographical correlation of…”
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Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria by Aidoo, M, Lalvani, A, Allsopp, C E, Plebanski, M, Meisner, S J, Krausa, P, Browning, M, Morris-Jones, S, Gotch, F, Fidock, D A

“…Several cellular and humoral mechanisms probably play a role in natural immunity to Plasmodium falciparum malaria, but the development of an effective vaccine…”
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Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria by McGuire, William, Hill, Adrian V. S, Allsopp, Catherine E. M, Greenwood, Brian M, Kwiatkowski, Dominic

“…Tumour-necrosis factor-alpha (TNF-alpha) is believed to have an important role in the pathogenesis of severe infectious disease and fatal cerebral malaria is…”
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Severe Malarial Anemia and Cerebral Malaria Are Associated with Different Tumor Necrosis Factor Promoter Alleles by McGuire, William, Knight, Julian C., Hill, Adrian V. S., Allsopp, Catherine E. M., Greenwood, Brian M., Kwiatkowski, Dominic

“…Experimental evidence implicates tumor necrosis factor (TNF) in the pathogenesis of malarial anemia, but there are few data relating to this hypothesis. This…”
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Association between an MHC Class II Allele and Clearance of Hepatitis B Virus in the Gambia by Thursz, Mark R, Kwiatkowski, Dominic, Allsopp, Catherine E.M, Greenwood, Brian M, Thomas, Howard C, Hill, Adrian V.S

“…Infection with the hepatitis B virus (HBV) may result in a number of conditions ranging from asymptomatic persistent carriage to fulminant hepatitis with liver…”
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A protein particle vaccine containing multiple malaria epitopes by Gilbert, Sarah C, Plebanski, Magdalena, Harris, Stephen J, Allsopp, Catherine E.M, Thomas, Rebecca, Layton, Guy T, Hill, Adrian V.S

“…Ty virus-like particles consist of a single protein species that can be produced in yeast. Recombinant Ty-VLPs carrying a string of up to 15 defined cytotoxic…”
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Molecular analysis of the association of HLA-B53 and resistance to severe malaria by Hill, Adrian V. S, Elvin, John, Willis, Anthony C, Aidoo, Michael, Allsopp, Catherine E. M, Gotch, Frances M, Ming Gao, X, Takiguchis, Masafumi, Greenwood, Brian M, Townsend, Alain R. M, McMichael, Andrew J, Whittle, Hilton C

“…The protective association between the human leukocyte antigen HLA-B53 and severe malaria was investigated by sequencing of peptides eluted from this molecule…”
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A flow cytometric method to assess antigen-specific proliferative responses of different subpopulations of fresh and cryopreserved human peripheral blood mononuclear cells by Allsopp, Catherine E.M, Nicholls, Stephen J, Langhorne, Jean

“…We have used PKH26 dye, which is incorporated stably into the membrane of cells, to determine, using flow cytometry, lymphocyte proliferative responses to the…”
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HLA class I typing by PCR: HLA-B27 and an African B27 subtype by Hill, A V, Allsopp, C E, Kwiatkowski, D, Anstey, N M, Greenwood, B M, McMichael, A J

“…We describe a rapid method of HLA class I typing using the polymerase chain reaction and oligonucleotide hybridisation that eliminates the requirements for…”
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Interethnic genetic differentiation in Africa : HLA class I antigens in the Gambia by ALLSOPP, C. E. M, HARDING, R. M, TAYLOR, C, BUNCE, M, KWIATKOWSKI, D, ANSTEY, N, BREWSTER, D, MCMICHAEL, A. J, GREENWOOD, B. M, HILL, A. V. S

“…A total of 752 individuals from The Gambia, west Africa who are representative of the major ethnic groups in the capital, Banjul, were serologically typed for…”
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Extensive Genetic Diversity in the HLA Class II Region of Africans, with a Focally Predominant Allele, DRB11304 by Adrian V. S. Hill, Catherine E. M. Allsopp, Kwiatkowski, Dominic, Taylor, Terrie E., Simon N. R. Yates, Anstey, Nicholas M., Wirima, Jack J., Brewster, David R., McMichael, Andrew J., Molyneux, Malcom E., Greenwood, Brian M.

“…Molecular HLA class II typing of >1700 individuals from The Gambia in West Africa and Malawi in South-Central Africa revealed a striking diversity of HLA…”
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Cytotoxic T cells in HIV2 seropositive Gambians : identification of a virus-specific MHC-restricted epitope by GOTCH, F, MCADAM, N, ALLSOPP, C. E. M, GALLIMORE, A, ELVIN, J, KIENY, M.-P, HILL, A. V. S, MCMICHAEL, A. J, WHITTLE, H. C

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Common West African HLA antigens are associated with protection from severe malaria by HILL, A. V. S, ALLSOPP, C. E. M, KWIATKOWSKI, D, ANSTEY, N. M, TWUMASI, P, ROWE, P. A, BENNETT, S, BREWSTER, D, MCMICHAEL, A. J, GREENWOOD, B. M

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A prospective study of the influence of alpha thalassaemia on morbidity from malaria and immune responses to defined Plasmodium falciparum antigens in Gambian children by Allen, S J, Rowe, P, Allsopp, C E, Riley, E M, Jakobsen, P H, Hill, A V, Greenwood, B M

“…The protective effect of alpha thalassaemia (-alpha/alpha alpha) against morbidity from falciparum malaria was assessed in a prospective study of rural Gambian…”
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Sequence analysis of HLA-Bw53, a common West African allele, suggests an origin by gene conversion of HLA-B35 by Allsopp, C E, Hill, A V, Kwiatkowski, D, Hughes, A, Bunce, M, Taylor, C J, Pazmany, L, Brewster, D, McMichael, A J, Greenwood, B M

“…In the West African population of the Gambia the class I antigen HLA-Bw53 is found at high frequency. We used the polymerase chain reaction to amplify cDNA…”
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The HLA-A,B,C genotype of the class I negative cell line Daudi reveals novel HLA-A and -B alleles by Browning, M J, Madrigal, J A, Krausa, P, Kowalski, H, Allsopp, C E, Little, A M, Turner, S, Adams, E J, Arnett, K L, Bodmer, W F

“…Daudi, a lymphoblastoid B cell line derived from an African Burkitt lymphoma does not express HLA-A,B,C antigens at the cell surface. Although HLA-A,B,C heavy…”
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