Search Results - "Allport, R."

Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle by Kelly, Kimberly A, Allport, Jennifer R, Tsourkas, Andrew, Shinde-Patil, Vivek R, Josephson, Lee, Weissleder, Ralph

“…Endothelial vascular adhesion molecule-1 (VCAM-1) is a critical component of the leukocyte–endothelial adhesion cascade, and its strict temporal and spatial…”
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Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction by JIQIU CHEN, TUNG, Ching-Hsuan, ALLPORT, Jennifer R, SI CHEN, WEISSLEDER, Ralph, HUANG, Paul L

“…We used a molecular probe activated by protease cleavage to image expression of matrix metalloproteinases (MMPs) in the heart after myocardial infarction. We…”
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Using participatory epidemiological techniques to estimate the relative incidence and impact on livelihoods of livestock diseases amongst nomadic pastoralists in Turkana South District, Kenya by Bett, B., Jost, C., Allport, R., Mariner, J.

“…A participatory epidemiological (PE) study was carried out with Turkana pastoralists in Turkana South District, Kenya, to determine the relative incidence of…”
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Noninvasive In Vivo Imaging of Monocyte Trafficking to Atherosclerotic Lesions by KIRCHER, Moritz F, GRIMM, Jan, SWIRSKI, Filip K, LIBBY, Peter, GERSZTEN, Robert E, ALLPORT, Jennifer R, WEISSLEDER, Ralph

“…Monocytes play a key role in atherogenesis, but their participation has been discerned largely via ex vivo analyses of atherosclerotic lesions. We sought to…”
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In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magnetooptical Probe by Tsourkas, Andrew, Shinde-Patil, Vivek R, Kelly, Kimberly A, Patel, Pratik, Wolley, Allison, Allport, Jennifer R, Weissleder, Ralph

“…It has been suggested that vascular cell adhesion molecule-1 (VCAM-1) could serve as an early marker for inflammation of the endothelium. The ability to…”
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In vivo imaging of gene and cell therapies by Allport, Jennifer R, Weissleder, Ralph

“…Molecular imaging can be broadly defined as the in vivo characterization and measurement of biological processes at the cellular and molecular level. In…”
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Monocytes Induce Reversible Focal Changes in Vascular Endothelial Cadherin Complex during Transendothelial Migration under Flow by Allport, Jennifer R., Muller, William A., Luscinskas, Francis W.

“…The vascular endothelial cell cadherin complex (VE-cadherin, α-, β-, and γ-catenin, and p120/p100) localizes to adherens junctions surrounding vascular…”
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SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration by Kelly, Kimberly A., Allport, Jennifer R., Yu, Amy M., Sinh, Sumita, Sage, E. Helene, Gerszten, Robert E., Weissleder, Ralph

“…VCAM‐1 is a cell surface molecule, which has been shown to mediate leukocyte adhesion to the endothelium and subsequent transmigration. Although VCAM‐1…”
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Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro by Allport, Jennifer R., Lim, Yaw‐Chyn, Shipley, J. Michael, Senior, Robert M., Shapiro, Steven D., Matsuyoshi, Norihisa, Vestweber, Dietmar, Luscinskas, Francis W.

“…Recent evidence has suggested a role for neutrophil proteases during certain inflammatory responses. We demonstrated previously that neutrophil proteases can…”
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Integrin-Mediated Neutrophil Adhesion and Retinal Leukostasis in Diabetes by Barouch, Fina Canas, Miyamoto, Kazuaki, Allport, Jennifer R, Fujita, Kenji, Bursell, Sven-Erik, Aiello, Lloyd Paul, Luscinskas, Francis William, Adamis, Anthony P

“…A critical early event in the pathogenesis of diabetic retinopathy is leukocyte adhesion to the diabetic retinal vasculature. The process is mediated, in part,…”
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The use of community-based animal health workers to strengthen disease surveillance systems in Tanzania by Allport, R, Mosha, R, Bahari, M, Swai, E, Catley, A

“…An 18 month trial was conducted in three districts of Arusha region, northern Tanzania, to assess the use of community-based animal health workers (CAHWs) in…”
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Murine Lewis Lung Carcinoma-Derived Endothelium Expresses Markers of Endothelial Activation and Requires Tumor-Specific Extracellular Matrix In Vitro by Allport, Jennifer R., Weissleder, Ralph

“…The purpose of the study was to identify characteristics specific to tumor-derived endothelium that may be important in tumor biology, or for the development…”
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Endothelial-dependent mechanisms regulate leukocyte transmigration: a process involving the proteasome and disruption of the vascular endothelial-cadherin complex at endothelial cell-to-cell junctions by Allport, J R, Ding, H, Collins, T, Gerritsen, M E, Luscinskas, F W

“…Although several adhesion molecules expressed on leukocytes (beta1 and beta2 integrins, platelet endothelial cell adhesion molecule 1 [PECAM-1], and CD47) and…”
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Bone Marrow-Derived lin−c-kit+Sca-1+ Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma by Shinde Patil, Vivek R., Friedrich, Erik B., Wolley, Allison E., Gerszten, Robert E., Allport, Jennifer R., Weissleder, Ralph

“…The development of tumor vasculature is thought to occur through two complementary processes: sprouting angiogenesis from preexisting blood vessels of the…”
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In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors by KIRCHER, Moritz F, ALLPORT, Jennifer R, GRAVES, Edward E, LOVE, Victoria, JOSEPHSON, Lee, LICHTMAN, Andrew H, WEISSLEDER, Ralph

“…Magnetic resonance imaging (MRI) allows noninvasive and three-dimensional visualization of whole organisms over time, and, therefore, would be ideally suited…”
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CD11b/CD18-coated microspheres attach to E-selectin under flow by Crutchfield, Karen L., Patil, Vivek R. Shinde, Campbell, Craig J., Parkos, Charles A., Allport, Jennifer R., Goetz, Douglas J.

“…Neutrophils can attach to E‐selectin under flow. Proposed ligands for E‐selectin carry SLex‐type glycans. The leukocyte β2 integrins are glycosylated with…”
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L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro by Allport, JR, Ding, HT, Ager, A, Steeber, DA, Tedder, TF, Luscinskas, FW

“…Current models of the multistep adhesion cascade for leukocyte-endothelial interactions predict loss of L-selectin from the leukocyte surface before…”
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Heterogeneity of Endothelial Cells from Different Organ Sites in T-Cell Subset Recruitment by Lim, Yaw-Chyn, Garcia-Cardena, Guillermo, Allport, Jennifer R., Zervoglos, Mandy, Connolly, Andrew J., Gimbrone, Michael A., Luscinskas, Francis W.

“…Chemokines and adhesion molecules play a critical role in the recruitment of leukocytes into specific organ sites. Little is known, however, regarding the…”
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Reduction by inhibitors of mono(ADP‐ribosyl)transferase of chemotaxis in human neutrophil leucocytes by inhibition of the assembly of filamentous actin by Allport, Jennifer R., Donnelly, Louise E., Hayes, Brian P., Murray, Stephen, Rendell, Nigel B., Ray, Keith P., MacDermot, John

“…1 Chemotaxis of human neutrophils is mediated by numerous agents [e.g. N‐formyl‐methionyl‐leucyl‐phenylalanine (FMLP) and platelet activating factor (PAF)]…”
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Murine neuronal progenitor cells are preferentially recruited to tumor vasculature via a4-integrin and SDF-1a dependent mechanisms by Allport, Jennifer R., Patil, Vivek R. Shinde, Weissleder, Ralph

“…Recent studies have described neuronal progenitor cell recruitment to tumors in vivo, however, the mechanisms mediating this recruitment are not yet…”
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