Search Results - "Alloza, I"

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    ANKRD55 and DHCR7 are novel multiple sclerosis risk loci by Alloza, I, Otaegui, D, de Lapuente, A Lopez, Antigüedad, A, Varadé, J, Núñez, C, Arroyo, R, Urcelay, E, Fernandez, O, Leyva, L, Fedetz, M, Izquierdo, G, Lucas, M, Oliver-Martos, B, Alcina, A, Saiz, A, Blanco, Y, Comabella, M, Montalban, X, Olascoaga, J, Matesanz, F, Vandenbroeck, K

    Published in Genes and immunity (01-04-2012)
    “…Multiple sclerosis (MS) shares some risk genes with other disorders hallmarked by an autoimmune pathogenesis, most notably IL2RA and CLEC16A . We analyzed 10…”
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    Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection by Vandenbroeck, K, Alloza, I, Swaminathan, B, Antigüedad, A, Otaegui, D, Olascoaga, J, Barcina, M G, de las Heras, V, Bartolomé, M, Fernández-Arquero, M, Arroyo, R, Alvarez-Lafuente, R, Cénit, M C, Urcelay, E

    Published in Genes and immunity (01-01-2011)
    “…In recent reports, IRF5 polymorphisms showed significant association with multiple sclerosis (MS) susceptibility in three studied populations and Irf5…”
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    Analysis of the IL28RA locus as genetic risk factor for multiple sclerosis by Lopez de Lapuente, A, Alloza, I, Goertsches, R, Zettl, U.K, Urcelay, E, Arroyo, R, Comabella, M, Montalban, X, Antigüedad, A, Vandenbroeck, K

    Published in Journal of neuroimmunology (01-04-2012)
    “…Abstract Recently, we reported an association between a SNP in IL28RA and MS. Here, we performed a fine-mapping of the IL28RA locus by genotyping 10…”
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    Replication of top markers of a genome-wide association study in multiple sclerosis in Spain by Cavanillas, M L, Fernández, O, Comabella, M, Alcina, A, Fedetz, M, Izquierdo, G, Lucas, M, Cénit, M C, Arroyo, R, Vandenbroeck, K, Alloza, I, García-Barcina, M, Antigüedad, A, Leyva, L, Gómez, C L, Olascoaga, J, Otaegui, D, Blanco, Y, Saiz, A, Montalbán, X, Matesanz, F, Urcelay, E

    Published in Genes and immunity (01-03-2011)
    “…Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with presumed autoimmune origin, triggered by genetic and environmental…”
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    The CTLA4 +49 A/GG-CT60G haplotype is associated with susceptibility to multiple sclerosis in Flanders by Suppiah, V, Alloza, I, Heggarty, S, Goris, A, Dubois, B, Carton, H, Vandenbroeck, K

    Published in Journal of neuroimmunology (01-07-2005)
    “…Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system white matter characterized by inflammation, demyelination and axonal…”
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    Journal Article
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    A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis by Vandenbroeck, K, Alvarez, J, Swaminathan, B, Alloza, I, Matesanz, F, Urcelay, E, Comabella, M, Alcina, A, Fedetz, M, Ortiz, M A, Izquierdo, G, Fernandez, O, Rodriguez-Ezpeleta, N, Matute, C, Caillier, S, Arroyo, R, Montalban, X, Oksenberg, J R, Antigüedad, A, Aransay, A

    Published in Genes and immunity (01-01-2012)
    “…Cytokine and cytokine receptor genes, including IL2RA , IL7R and IL12A , are known risk factors for multiple sclerosis (MS). Excitotoxic oligodendroglial death…”
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    The metallopeptide antibiotic bacitracin inhibits interleukin-12 αβ and β2 secretion by Alloza, I., Vandenbroeck, K.

    Published in Journal of pharmacy and pharmacology (01-02-2005)
    “…The metalloantibiotic bacitracin is a known inhibitor of protein disulfide isomerase (PDI). The disulfide‐linked interleukin‐12 (IL‐12) αβ‐heterodimer and…”
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    Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges by Vandenbroeck, Koen, Alloza, Iraide, Gadina, Massimo, Matthys, Patrick

    Published in Journal of pharmacy and pharmacology (01-02-2004)
    “…ABSTRACT Interleukin‐12 (IL‐12) and the more recently discovered IL‐23 and IL‐27 constitute a unique family of structurally related, heterodimeric cytokines…”
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    Polymorphisms in the interleukin-4 and IL-4 receptor genes and multiple sclerosis: a study in Spanish-Basque, Northern Irish and Belgian populations by Suppiah, V., Goris, A., Alloza, I., Heggarty, S., Dubois, B., Carton, H., Antigüedad, A., Mendibe, M., McDonnell, G., Droogan, A., Hawkins, S., Graham, C., Vandenbroeck, K.

    Published in International journal of immunogenetics (01-12-2005)
    “…Summary Cytokine gene polymorphisms are known to influence susceptibility and disease course of many autoimmune diseases. Multiple sclerosis (MS) is a chronic…”
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    IL7RA polymorphisms and chronic inflammatory arthropathies by O'Doherty, C., Alloza, I., Rooney, M., Vandenbroeck, K.

    Published in Tissue antigens (01-11-2009)
    “…The C allele of a single nucleotide polymorphism (SNP), rs6897932, located in the interleukin‐7 receptor alpha chain (IL7RA) was recently found to be…”
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    Atlas VPM: two decades informing on unwarranted variations in health care in Spain by Angulo-Pueyo, Ester, Comendeiro-Maaløe, Micaela, Estupiñán-Romero, Francisco, Martínez-Lizaga, Natalia, Ridao-López, Manuel, González-Galindo, Javier, Launa-Garcés, Ramón, Seral-Rodríguez, Miriam, Bernal-Delgado, Enrique

    Published in Research in Health Services & Regions (20-07-2022)
    “…Since the early 2000's, the Atlas of Variations in Medical Practice in the Spanish National Health System (namely, Atlas VPM) has been analysing and informing…”
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    The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion by Alloza, I, Vandenbroeck, K

    Published in Journal of pharmacy and pharmacology (01-02-2005)
    “…The metalloantibiotic bacitracin is a known inhibitor of protein disulfide isomerase (PDI). The disulfide-linked interleukin-12 (IL-12) alphabeta-heterodimer…”
    Get full text
    Journal Article
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    Polymorphisms in the interferon‐γ/interleukin‐26 gene region contribute to sex bias in susceptibility to rheumatoid arthritis by Vandenbroeck, K., Cunningham, S., Goris, A., Alloza, I., Heggarty, S., Graham, C., Bell, A., Rooney, M.

    Published in Arthritis and rheumatism (01-10-2003)
    “…Objective To determine whether polymorphisms in the interferon‐γ (IFNγ)/interleukin‐26 (IL‐26; formerly, AK155) gene cluster contribute to sex‐based…”
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    IFNG polymorphisms are associated with gender differences in susceptibility to multiple sclerosis by Kantarci, O H, Goris, A, Hebrink, D D, Heggarty, S, Cunningham, S, Alloza, I, Atkinson, E J, de Andrade, M, McMurray, C T, Graham, C A, Hawkins, S A, Billiau, A, Dubois, B, Weinshenker, B G, Vandenbroeck, K

    Published in Genes and immunity (01-03-2005)
    “…Interferon-gamma (IFNgamma) treatment is deleterious in multiple sclerosis (MS). MS occurs twice as frequently in women as in men. IFNgamma expression varies…”
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    The CTLA4 + 49 A/G G– CT60 G haplotype is associated with susceptibility to multiple sclerosis in Flanders by Suppiah, V., Alloza, I., Heggarty, S., Goris, A., Dubois, B., Carton, H., Vandenbroeck, K.

    Published in Journal of neuroimmunology (2005)
    “…Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system white matter characterized by inflammation, demyelination and axonal…”
    Get full text
    Journal Article
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    The Conserved Helix C Region in the Superfamily of Interferon-γ/Interleukin-10-related Cytokines Corresponds to a High-affinity Binding Site for the HSP70 Chaperone DnaK by Vandenbroeck, Koen, Alloza, Iraide, Brehmer, Dirk, Billiau, Alfons, Proost, Paul, McFerran, Neil, Rüdiger, Stefan, Walker, Brian

    Published in The Journal of biological chemistry (12-07-2002)
    “…HSP70 chaperones mediate protein folding by ATP-dependent interaction with short linear peptide segments that are exposed on unfolded proteins. The mode of…”
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