Search Results - "Allison, Thomas F."
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1
Identification of neural oscillations and epileptiform changes in human brain organoids
Published in Nature neuroscience (01-10-2021)“…Brain organoids represent a powerful tool for studying human neurological diseases, particularly those that affect brain growth and structure. However, many…”
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2
Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells
Published in Stem cell reports (08-11-2016)“…Genetic changes in human pluripotent stem cells (hPSCs) gained during culture can confound experimental results and potentially jeopardize the outcome of…”
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3
Synthetically modified mRNA for efficient and fast human iPS cell generation and direct transdifferentiation to myoblasts
Published in Biochemical and biophysical research communications (06-05-2016)“…Synthetic mRNA transfection enables efficient and controlled gene expression in human cells, without genome integrations. Further, modifications to the mRNA…”
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4
Defining Transcriptional Signatures of Human Hair Follicle Cell States
Published in Journal of investigative dermatology (01-04-2020)“…The epidermis and its appendage, the hair follicle, represent an elegant developmental system in which cells are replenished with regularity because of…”
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5
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
Published in Nature communications (15-05-2018)“…The International Stem Cell Initiative compared several commonly used approaches to assess human pluripotent stem cells (PSC). PluriTest predicts pluripotency…”
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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells
Published in Stem cell reports (05-06-2018)“…Human embryonic stem cells (hESCs) display substantial heterogeneity in gene expression, implying the existence of discrete substates within the stem cell…”
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7
The reprogramming method matters
Published in Nature biomedical engineering (01-10-2017)“…The genetic, epigenetic and transcriptomic profiles of human induced pluripotent stem cells are shaped by the reprogramming route…”
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Publisher Correction: Stem cells: The reprogramming method matters
Published in Nature biomedical engineering (2018)“…In the version of this News and Views article originally published, an erroneous hyphen was included in the term ‘human-induced pluripotent stem cells’; it…”
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Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells
Published in Scientific reports (14-07-2015)“…Maternal exposure during pregnancy to toxins can occasionally lead to miscarriage and malformation. It is currently thought that toxins pass through the…”
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Delineating the mechanisms behind fate decisions of human embryonic stem cells
Published 01-01-2015“…Human embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos. Once explanted and cultured in vitro under appropriate…”
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Dissertation