Search Results - "Allinson, Kieren S.J"

[11C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy by Passamonti, Luca, Rodríguez, Patricia Vázquez, Hong, Young T, Allinson, Kieren S.J, Bevan-Jones, W Richard, Williamson, David, Jones, P Simon, Arnold, Robert, Borchert, Robin J, Surendranathan, Ajenthan, Mak, Elijah, Su, Li, Fryer, Tim D, Aigbirhio, Franklin I, OʼBrien, John T, Rowe, James B

“…OBJECTIVEWe tested whether in vivo neuroinflammation relates to the distinctive distributions of pathology in Alzheimer disease (AD) and progressive…”
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Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome by Jabbari, Edwin, Holland, Negin, Chelban, Viorica, Jones, P Simon, Lamb, Ruth, Rawlinson, Charlotte, Guo, Tong, Costantini, Alyssa A, Tan, Manuela M X, Heslegrave, Amanda J, Roncaroli, Federico, Klein, Johannes C, Ansorge, Olaf, Allinson, Kieren S J, Jaunmuktane, Zane, Holton, Janice L, Revesz, Tamas, Warner, Thomas T, Lees, Andrew J, Zetterberg, Henrik, Russell, Lucy L, Bocchetta, Martina, Rohrer, Jonathan D, Williams, Nigel M, Grosset, Donald G, Burn, David J, Pavese, Nicola, Gerhard, Alexander, Kobylecki, Christopher, Leigh, P Nigel, Church, Alistair, Hu, Michele T M, Woodside, John, Houlden, Henry, Rowe, James B, Morris, Huw R

“…Atypical parkinsonian syndromes (APS), including progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA), may be…”
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Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study by Jabbari, Edwin, Koga, Shunsuke, Valentino, Rebecca R, Reynolds, Regina H, Ferrari, Raffaele, Tan, Manuela M X, Rowe, James B, Dalgard, Clifton L, Scholz, Sonja W, Dickson, Dennis W, Warner, Thomas T, Revesz, Tamas, Höglinger, Günter U, Ross, Owen A, Ryten, Mina, Hardy, John, Shoai, Maryam, Morris, Huw R, Mok, Kin Y., Murphy, David P., Al-Sarraj, Safa, Troakes, Claire, Gentleman, Steve M., Allinson, Kieren S.J., Jaunmuktane, Zane, Holton, Janice L., Lees, Andrew J., Morris, Christopher M., Compta, Yaroslau, Gelpi, Ellen, van Swieten, John C., Rajput, Alex, Ferguson, Leslie, Cookson, Mark R., Gibbs, J. Raphael, Blauwendraat, Cornelis, Ding, Jinhui, Chia, Ruth, Traynor, Bryan J., Pantelyat, Alexander, Viollet, Coralie, Pletnikova, Olga, Troncoso, Juan C., Rosenthal, Liana S., Boxer, Adam L., Respondek, Gesine, Arzberger, Thomas, Roeber, Sigrun, Giese, Armin, Burn, David J., Pavese, Nicola, Gerhard, Alexander, Kobylecki, Christopher, Leigh, P. Nigel, Church, Alistair, T.M. Hu, Michele

“…The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants of survival in…”
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[18F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia by Bevan-Jones, W R, Cope, Thomas E, Jones, P Simon, Passamonti, Luca, Hong, Young T, Fryer, Tim D, Arnold, Robert, Allinson, Kieren S J, Coles, Jonathan P, Aigbirhio, Franklin I, Patterson, Karalyn, O’Brien, John T, Rowe, James B

“…IntroductionSemantic dementia, including the semantic variant of primary progressive aphasia (svPPA), is strongly associated with TAR-DNA binding protein 43…”
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Neuropathological findings in two patients with fatal COVID‐19 by Jensen, M. P., Le Quesne, J., Officer‐Jones, L., Teodòsio, A., Thaventhiran, J., Ficken, C., Goddard, M., Smith, C., Menon, D., Allinson, K. S. J.

“…Case 1 demonstrated multi‐territorial cerebral vascular injury with associated cerebral thrombotic microangiopathy; case 2 demonstrated a brainstem…”
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Venous-plexus-associated lymphoid hubs support meningeal humoral immunity by Fitzpatrick, Zachary, Ghabdan Zanluqui, Nagela, Rosenblum, Jared S., Tuong, Zewen Kelvin, Lee, Colin Y. C., Chandrashekhar, Vikram, Negro-Demontel, Maria Luciana, Stewart, Andrew P., Posner, David A., Buckley, Monica, Allinson, Kieren S. J., Mastorakos, Panagiotis, Chittiboina, Prashant, Maric, Dragan, Donahue, Danielle, Helmy, Adel, Tajsic, Tamara, Ferdinand, John R., Portet, Anais, Peñalver, Ana, Gillman, Eleanor, Zhuang, Zhengping, Clatworthy, Menna R., McGavern, Dorian B.

“…There is increasing interest in how immune cells in the meninges—the membranes that surround the brain and spinal cord—contribute to homeostasis and disease in…”
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Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome by Vaughan, David P, Fumi, Riona, Theilmann Jensen, Marte, Hodgson, Megan, Georgiades, Tatiana, Wu, Lesley, Lux, Danielle, Obrocki, Ruth, Lamoureux, Jennifer, Ansorge, Olaf, Allinson, Kieren S J, Warner, Thomas T, Jaunmuktane, Zane, Misbahuddin, Anjum, Leigh, P Nigel, Ghosh, Boyd C P, Bhatia, Kailash P, Church, Alistair, Kobylecki, Christopher, Hu, Michele T M, Rowe, James B, Blauwendraat, Cornelis, Morris, Huw R, Jabbari, Edwin

“…Seed amplification assay (SAA) testing has been developed as a biomarker for the diagnosis of α-synuclein-related neurodegenerative disorders. The objective of…”
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Progression of atypical parkinsonian syndromes: PROSPECT-M-UK study implications for clinical trials by Street, Duncan, Jabbari, Edwin, Costantini, Alyssa, Jones, P Simon, Holland, Negin, Rittman, Timothy, Jensen, Marte T, Chelban, Viorica, Goh, Yen Y, Guo, Tong, Heslegrave, Amanda J, Roncaroli, Federico, Klein, Johannes C, Ansorge, Olaf, Allinson, Kieren S J, Jaunmuktane, Zane, Revesz, Tamas, Warner, Thomas T, Lees, Andrew J, Zetterberg, Henrik, Russell, Lucy L, Bocchetta, Martina, Rohrer, Jonathan D, Burn, David J, Pavese, Nicola, Gerhard, Alexander, Kobylecki, Christopher, Leigh, P Nigel, Church, Alistair, Hu, Michele T M, Houlden, Henry, Morris, Huw, Rowe, James B

“…Abstract The advent of clinical trials of disease-modifying agents for neurodegenerative disease highlights the need for evidence-based end point selection…”
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Evidence of impaired macroautophagy in human degenerative cervical myelopathy by Smith, Sam S., Young, Adam M. H., Davies, Benjamin M., Takahashi, Hitoshi, Allinson, Kieren S. J., Kotter, Mark R. N.

“…Degenerative cervical myelopathy (DCM) is a common progressive disease of the spinal cord which can cause tetraplegia. Despite its prevalence, few studies have…”
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In Vivo 18 F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy by Malpetti, Maura, Kaalund, Sanne S, Tsvetanov, Kamen A, Rittman, Timothy, Briggs, Mayen, Allinson, Kieren S J, Passamonti, Luca, Holland, Negin, Jones, P Simon, Fryer, Tim D, Hong, Young T, Kouli, Antonina, Bevan-Jones, W Richard, Mak, Elijah, Savulich, George, Spillantini, Maria Grazia, Aigbirhio, Franklin I, Williams-Gray, Caroline H, O'Brien, John T, Rowe, James B

“…Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuroglial tau pathology. A new staging system for PSP pathology…”
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In Vivo 18F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy by Malpetti, Maura, Kaalund, Sanne S, Tsvetanov, Kamen A, Rittman, Timothy, Briggs, Mayen, Allinson, Kieren SJ, Passamonti, Luca, Holland, Negin, Jones, P Simon, Fryer, Tim D, Hong, Young T, Kouli, Antonina, Bevan-Jones, W Richard, Mak, Elijah, Savulich, George, Spillantini, Maria Grazia, Aigbirhio, Franklin I, Williams-Gray, Caroline H, O'Brien, John T, Rowe, James B

“…Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuroglial tau pathology. A new staging system for PSP pathology…”
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A case report of metastatic renal cell carcinoma causing corticobasal syndrome by Jensen, Melanie P, Rowe, James B, Allinson, Kieren S J

“…We present a case report of a patient with a history of renal cell carcinoma in which corticobasal syndrome had been diagnosed ante-mortem. However,…”
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Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates by Ling, Helen, Gelpi, Ellen, Davey, Karen, Jaunmuktane, Zane, Mok, Kin Y., Jabbari, Edwin, Simone, Roberto, R’Bibo, Lea, Brandner, Sebastian, Ellis, Matthew J., Attems, Johannes, Mann, David, Halliday, Glenda M., Al-Sarraj, S., Hedreen, J., Ironside, James W., Kovacs, Gabor G., Kovari, E., Love, S., Vonsattel, Jean Paul G., Allinson, Kieren S. J., Hansen, Daniela, Bradshaw, Teisha, Setó-Salvia, Núria, Wray, Selina, de Silva, Rohan, Morris, Huw R., Warner, Thomas T., Hardy, John, Holton, Janice L., Revesz, Tamas

“…Corticobasal degeneration typically progresses gradually over 5–7 years from onset till death. Fulminant corticobasal degeneration cases with a rapidly…”
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Clinicopathological co-occurrence of Fahr's disease and dementia with Lewy bodies by Jensen, Melanie P, Spasic-Boskovic, Olivera, Rowe, James B, Galton, Clare, Allinson, Kieren S J

“…We present the clinicopathological findings of a case of combined Fahr's disease (FD) and dementia with Lewy bodies (DLB), associated with a novel pathogenic…”
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Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity by Kaalund, Sanne Simone, Passamonti, Luca, Allinson, Kieren S J, Murley, Alexander G, Robbins, Trevor W, Spillantini, Maria Grazia, Rowe, James B

“…The locus coeruleus is the major source of noradrenaline to the brain and contributes to a wide range of physiological and cognitive functions including…”
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Intracranial gossypiboma 9 years after intracranial pressure bolt insertion: illustrative case by Loh, Ryan T. S., Matys, Tomasz, Allinson, Kieren S. J., Santarius, Thomas

“…BACKGROUND Resorbable hemostatic agents left behind postoperatively occasionally result in granulomatous space-occupying lesions known as “gossypibomas.” The…”
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Rosette-forming glioneuronal tumor with dissemination throughout the ventricular system: a case report by Allinson, Kieren S J, O'Donovan, Dominic G, Jena, Rajesh, Cross, Justin J, Santarius, Thomas S

“…A 33-year-old female was found to have a rosette-forming glioneuronal tumor (RGNT) occurring within the fourth ventricle with multifocal extension to the third…”
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A 73 Year-Old Man with a Mass at the Foramen Magnum by Allinson, Kieren S J, Kolias, Angelos G, Philippou, Yiannis, Bulters, Diederik O, Fisher, Cyril, Perry, Arie, Dean, Andrew F

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The genome of the sparganosis tapeworm Spirometra erinaceieuropaei isolated from the biopsy of a migrating brain lesion by Bennett, Hayley M, Mok, Hoi Ping, Gkrania-Klotsas, Effrossyni, Tsai, Isheng J, Stanley, Eleanor J, Antoun, Nagui M, Coghlan, Avril, Harsha, Bhavana, Traini, Alessandra, Ribeiro, Diogo M, Steinbiss, Sascha, Lucas, Sebastian B, Allinson, Kieren S J, Price, Stephen J, Santarius, Thomas S, Carmichael, Andrew J, Chiodini, Peter L, Holroyd, Nancy, Dean, Andrew F, Berriman, Matthew

“…Sparganosis is an infection with a larval Diphyllobothriidea tapeworm. From a rare cerebral case presented at a clinic in the UK, DNA was recovered from a…”
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