Search Results - "Alleyne, Cargill H"
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Post-Injury Administration of Tert-butylhydroquinone Attenuates Acute Neurological Injury After Intracerebral Hemorrhage in Mice
Published in Journal of molecular neuroscience (01-04-2016)“…Intracerebral hemorrhage (ICH) is a severe form of stroke with substantial public health impact. Notably, there is no effective treatment for ICH. Given the…”
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2
Resveratrol Attenuates Neurodegeneration and Improves Neurological Outcomes after Intracerebral Hemorrhage in Mice
Published in Frontiers in cellular neuroscience (08-08-2017)“…Intracerebral hemorrhage (ICH) is a devastating type of stroke with a substantial public health impact. Currently, there is no effective treatment for ICH. The…”
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3
Augmented expression of TSPO after intracerebral hemorrhage: a role in inflammation?
Published in Journal of neuroinflammation (17-06-2016)“…Intracerebral hemorrhage (ICH) is a potentially fatal stroke subtype accounting for 10-15 % of all strokes. Despite neurosurgical intervention and supportive…”
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4
TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebral hemorrhage in mice
Published in Neuroscience letters (10-05-2013)“…•R-7050, a novel TNFR antagonist, reduces neurovascular injury after ICH.•Pharmacological inhibition of TNFR improves outcomes after ICH.•TNFR may represent a…”
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5
Astrocyte-specific expression of survivin after intracerebral hemorrhage in mice: a possible role in reactive gliosis?
Published in Journal of neurotrauma (10-12-2012)“…Intracerebral hemorrhage (ICH), the most common form of hemorrhagic stroke, accounts for up to 15% of all strokes. Despite maximal surgical intervention and…”
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Letter: Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms
Published in Neurosurgery (01-09-2017)Get full text
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7
Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation
Published in The Journal of experimental medicine (01-10-2018)“…Spontaneous intracerebral hemorrhage (ICH) produces the highest acute mortality and worst outcomes of all stroke subtypes. Hematoma volume is an independent…”
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Cerebral vascular malformations in hereditary hemorrhagic telangiectasia
Published in Journal of neurosurgery (01-01-2014)“…Hereditary hemorrhagic telangiectasia (HHT) is a hereditary disorder characterized by mucocutaneous telangiectasias, frequent nosebleeds, and visceral…”
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Necrostatin-1 Reduces Neurovascular Injury after Intracerebral Hemorrhage
Published in International Journal of Cell Biology (2014)“…Intracerebral hemorrhage (ICH) is the most common form of hemorrhagic stroke, accounting for 15% of all strokes. ICH has the highest acute mortality and the…”
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10
Cephalad Migration of Intradural Bullet from Thoracic Spine to Cervical Spine
Published in World neurosurgery (01-11-2018)“…There are few reported instances of intraspinal migration of a bullet fragment. The majority of these migrations occur caudally, typically below the level of…”
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11
Curcumin attenuates vascular inflammation and cerebral vasospasm after subarachnoid hemorrhage in mice
Published in Antioxidants & redox signaling (01-01-2009)“…Cerebral vasospasm is a major cause of death and disability after subarachnoid hemorrhage (SAH); however, clinical therapies to limit the development of…”
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12
Sellar/Suprasellar Ganglioglioma: Clinical Image
Published in World neurosurgery (01-12-2019)“…This report presents a rare presentation of a ganglioglioma in the sellar/suprasellar region. On the basis of the patient's presentation and imaging…”
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13
Age-Dependent Lethality in Novel Transgenic Mouse Models of Central Nervous System Arteriovenous Malformations
Published in Stroke (1970) (01-05-2012)“…The lack of an appropriate animal model has been a limitation in studying hemorrhage from arteriovenous malformations (AVMs) in the central nervous system…”
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14
The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Confers Acute Neuroprotection After Intracerebral Hemorrhage in Mice
Published in Translational stroke research (01-04-2016)“…Spontaneous intracerebral hemorrhage (ICH) is a stroke subtype with no effective treatment. Though ICH is known to induce severe neurological damage, the…”
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15
Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes
Published in Free radical biology & medicine (15-10-2008)“…Intracerebral hemorrhage (ICH) is a devastating neurological injury associated with significant mortality. Astrocytic inflammation may contribute to the…”
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16
Critical Appraisal of Randomized Controlled Trials on Unruptured Brain Arteriovenous Malformations
Published in World neurosurgery (01-10-2022)“…Brain arteriovenous malformations management remains controversial despite the numerous, available treatment options. Randomized controlled trials (RCTs)…”
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Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells
Published in BMC cancer (13-03-2015)“…Malignant glioma is one of the most devastating tumors in adults with poor patient prognosis. Notably, glioma often exhibits resistance to conventional…”
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Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells
Published in Glia (15-11-2010)“…Intracerebral hemorrhage (ICH) induces neurovascular injury via poorly defined mechanisms. The aim of this study was to determine whether gliovascular…”
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[ 125 I]IodoDPA-713 Binding to 18 kDa Translocator Protein (TSPO) in a Mouse Model of Intracerebral Hemorrhage: Implications for Neuroimaging
Published in Frontiers in neuroscience (22-02-2018)“…Intracerebral hemorrhage (ICH) is a fatal stroke subtype with significant public health impact. Although neuroinflammation is a leading cause of neurological…”
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20
Nail-gun head trauma: A comprehensive review of the literature
Published in The journal of trauma and acute care surgery (01-10-2012)Get full text
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