Search Results - "Alleti, Ramesh"
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Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors
Published in Bioorganic & medicinal chemistry (01-09-2013)“…Probes for use in time-resolved fluorescence competitive binding assays at melanocortin receptors based on the parental ligands MSH(4), MSH(7), and NDP-α-MSH…”
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Journal Article -
2
Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors
Published in Bioorganic & medicinal chemistry letters (15-04-2010)“…A labeled variant of MSH(4), a tetrapeptide that binds to the human melanocortin 4 receptor (hMC4R) with low μM affinity, was prepared by solid-phase synthesis…”
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Journal Article -
3
gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride
Published in Chemical communications (Cambridge, England) (07-02-2005)“…2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent…”
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Journal Article -
4
Imidazolium-based polymer supported gadolinium triflate as a heterogeneous recyclable Lewis acid catalyst for Michael additions
Published in Tetrahedron letters (19-05-2008)“…A heterogeneous Lewis acid catalytic system has been developed by incorporating gadolinium triflate on to poly[styrene-…”
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Journal Article -
5
Gadolinium triflate: an efficient and convenient catalyst for acetylation of alcohols and amines
Published in Journal of molecular catalysis. A, Chemical (01-02-2005)“…Gadolinium triflate (Gd(OTf) 3) was found to be a simple and efficient catalyst for the acetylation of alcohols and amines. Acetylation reactions using acetic…”
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Journal Article -
6
A Solanesol-Derived Scaffold for Multimerization of Bioactive Peptides
Published in Journal of organic chemistry (03-09-2010)“…A flexible molecular scaffold bearing varying numbers of terminal alkyne groups was synthesized in five steps from solanesol. R(CO)-MSH(4)-NH2 ligands, which…”
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Journal Article -
7
A sucrose-derived scaffold for multimerization of bioactive peptides
Published in Bioorganic & medicinal chemistry (01-11-2011)“…A spherical molecular scaffold bearing eight terminal alkyne groups was synthesized in one step from sucrose. One or more copies of a tetrapeptide azide,…”
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Journal Article -
8
Demonstration of a sucrose-derived contrast agent for magnetic resonance imaging of the GI tract
Published in Bioorganic & medicinal chemistry letters (01-04-2013)“…A scaffold bearing eight terminal alkyne groups was synthesized from sucrose, and copies of an azide-terminated Gd–DOTA complex were attached via…”
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Journal Article -
9
Synthesis and Characterization of a Eu-DTPA-PEGO-MSH(4) Derivative for Evaluation of Binding of Multivalent Molecules to Melanocortin Receptors1
Published in Bioorganic & medicinal chemistry letters (04-03-2010)“…A labeled variant of MSH(4), a tetrapeptide that binds to the human melanocortin 4 receptor (hMC4R) with low µM affinity, was prepared by solid phase synthesis…”
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Journal Article -
10
Design, Synthesis, and Testing of a Molecular Truck for Colonic Delivery of 5‑Aminosalicylic Acid
Published in ACS medicinal chemistry letters (13-09-2012)“…A molecular scaffold bearing eight terminal alkyne groups was synthesized from sucrose. Eight copies of an azide-terminated, azo-linked precursor to…”
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Journal Article -
11
Lewis acid catalysis in organic synthesis
Published 01-01-2007“…Gadolinium triflate (Gd(OTf)3) was found to be a simple and efficient catalyst for the acetylation of alcohols and amines in both conventional organic solvents…”
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Dissertation -
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Lewis acid catalysis in organic synthesis
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Dissertation