Search Results - "Allende, Jorge E"
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Protein kinase CK2 as an ectokinase: The role of the regulatory CK2β subunit
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-2008)“…Protein kinase CK2 (also known as casein kinase 2) is present in the cytoplasm, nuclei, and several other organelles. In addition, this enzyme has been found…”
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The First Armadillo Repeat Is Involved in the Recognition and Regulation of β-Catenin Phosphorylation by Protein Kinase CK1
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2006)“…Multiple phosphorylation of β-catenin by glycogen synthase kinase 3 (GSK3) in the Wnt pathway is primed by CK1 through phosphorylation of Ser-45, which lacks a…”
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A Noncanonical Sequence Phosphorylated by Casein Kinase 1 in β-Catenin May Play a Role in Casein Kinase 1 Targeting of Important Signaling Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2003)“…Protein kinase casein kinase 1 (CK1) phosphorylates Ser-45 of β-catenin, "priming" the subsequent phosphorylation by glycogen synthase-3 of residues 41, 37,…”
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Uncoupling Substrate and Activation Functions of Rotavirus NSP5: Phosphorylation of Ser-67 by Casein Kinase 1 Is Essential for Hyperphosphorylation
Published in Proceedings of the National Academy of Sciences - PNAS (16-11-2004)“…Rotavirus NSP5 is a nonstructural protein that localizes in viroplasms of virus-infected cells. NSP5 interacts with NSP2 and undergoes a complex…”
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Protein Kinase Casein Kinase 2 Holoenzyme Produced Ectopically in Human Cells Can Be Exported to the External Side of the Cellular Membrane
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2005)“…Ectokinases can phosphorylate extracellular proteins and external domains of membrane proteins influencing cell adhesion, movement, and cellular interactions…”
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Academies active in education
Published in Science (American Association for the Advancement of Science) (29-08-2008)Get full text
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Dual effect of lysine-rich polypeptides on the activity of protein kinase CK2
Published in Journal of cellular biochemistry (15-05-2003)“…Protein kinase CK2 (casein kinase II) is normally a heterotetramer composed of catalytic (α, α′) and regulatory subunits (β). CK2 is able to phosphorylate a…”
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p53 codon 72 polymorphism and risk of cervical cancer
Published in Biological research (2003)“…Storey et al. (1998) implicated the proline/argine polymorphism of the codon 72 of the tumor-suppressor gene p53 in the development of cervical cancer (CC)…”
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Impaired hyperphosphorylation of rotavirus NSP5 in cells depleted of casein kinase 1α is associated with the formation of viroplasms with altered morphology and a moderate decrease in virus replication
Published in Journal of general virology (01-10-2007)“…The rotavirus (RV) non-structural protein 5, NSP5, is encoded by the smallest of the 11 genomic segments and localizes in ‘viroplasms’, cytoplasmic inclusion…”
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Chemical Dissection of the APC Repeat 3 Multistep Phosphorylation by the Concerted Action of Protein Kinases CK1 and GSK3
Published in Biochemistry (Easton) (23-10-2007)“…A crucial event in machinery controlled by Wnt signaling is the association of β-catenin with the adenomatous polyposis coli (APC) protein, which is essential…”
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CK2α/CK1α chimeras are sensitive to regulation by the CK2β subunit
Published in Molecular and cellular biochemistry (2008)“…The effect of CK2β on the activity of CK2α and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve…”
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Generation of protein kinase Ck1α mutants which discriminate between canonical and non-canonical substrates
Published in Biochemical journal (15-10-2005)“…Protein kinase CK1 denotes a family of pleiotropic serine/threonine protein kinases implicated in a variety of cellular functions. Typically, CK1 acts as a…”
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Activity of recombinant .alpha. and .beta. subunits of casein kinase II from Xenopus laevis
Published in Biochemistry (Easton) (01-07-1993)“…Casein kinase II (CKII) is a ubiquitous protein kinase, found predominantly in cell nuclei, which has two subunits in a tetrameric alpha 2 beta 2 or alpha…”
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Minimal CK2 activity required for yeast growth
Published in Molecular and cellular biochemistry (01-06-2005)“…Protein kinase CK2 is essential for the growth of Saccharomyces cerevisiae. Yeast cells that lack the functional genes coding for both the catalytic subunits…”
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Role of the carboxyl terminus on the catalytic activity of protein kinase CK2α subunit
Published in FEBS letters (06-11-2002)“…Protein kinase CK2 (also known as casein kinase 2) has catalytic (α, α′) and regulatory (β) subunits. The role of carboxyl amino acids in positions from 324 to…”
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Human papillomavirus-16 E7 protein inhibits the DNA interaction of the TATA binding transcription factor
Published in Journal of cellular biochemistry (2002)“…Previous studies have shown that the HPV‐16 E7 protein interacts with TBP. This interaction was found to take place through residues in the carboxy terminal…”
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Six decades of scientific pan-Americanism - an interview with Jorge E. Allende
Published in The International journal of developmental biology (2021)“…Jorge E. Allende is a biochemist trained in the United States of America who has been a professor at the University of Chile since 1961. He has served in many…”
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Phosphorylation of yeast TBP by protein kinase CK2 reduces its specific binding to DNA
Published in FEBS letters (29-01-1999)“…Protein kinase CK2 is a ubiquitous Ser/Thr kinase which phosphorylates a large number of proteins including several transcription factors. Recombinant Xenopus…”
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Structural Features Underlying the Multisite Phosphorylation of the A Domain of the NF-AT4 Transcription Factor by Protein Kinase CK1
Published in Biochemistry (Easton) (15-01-2002)“…The phosphorylation and dephosphorylation of the NF-AT family of transcription factors play a key role in the activation of T lymphocytes and in the control of…”
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