Search Results - "Allen Chan, K.C."

Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer by Chan, K.C. Allen, Woo, John K.S, King, Ann, Zee, Benny C.Y, Lam, W.K. Jacky, Chan, Stephen L, Chu, Sam W.I, Mak, Constance, Tse, Irene O.L, Leung, Samantha Y.M, Chan, Gloria, Hui, Edwin P, Ma, Brigette B.Y, Chiu, Rossa W.K, Leung, Sing-Fai, van Hasselt, Andrew C, Chan, Anthony T.C, Lo, Y.M. Dennis

“…Circulating Epstein–Barr virus DNA was measured in 20,174 asymptomatic participants in Hong Kong; 34 of 309 with positive results had nasopharyngeal cancer…”
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Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742) by Ma, Brigette B Y, Lim, Wan-Teck, Goh, Boon-Cher, Hui, Edwin P, Lo, Kwok-Wai, Pettinger, Adam, Foster, Nathan R, Riess, Jonathan W, Agulnik, Mark, Chang, Alex Y C, Chopra, Akhil, Kish, Julie A, Chung, Christine H, Adkins, Douglas R, Cullen, Kevin J, Gitlitz, Barbara J, Lim, Dean W, To, Ka-Fai, Chan, K C Allen, Lo, Y M Dennis, King, Ann D, Erlichman, Charles, Yin, Jun, Costello, Brian A, Chan, Anthony T C

“…Purpose This multinational study evaluated the antitumor activity of nivolumab in nasopharyngeal carcinoma (NPC). Tumor and plasma-based biomarkers were…”
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Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin by Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Cell-free DNA (cfDNA) in human plasma is a class of biomarkers with many current and potential future diagnostic applications. Recent studies have shown that…”
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Analysis of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Cancer After Chemoradiation to Identify High-Risk Patients for Adjuvant Chemotherapy: A Randomized Controlled Trial by Chan, Anthony T C, Hui, Edwin P, Ngan, Roger K C, Tung, Stewart Y, Cheng, Ashley C K, Ng, Wai T, Lee, Victor H F, Ma, Brigette B Y, Cheng, Hoi C, Wong, Frank C S, Loong, Herbert H F, Tong, Macy, Poon, Darren M C, Ahuja, Anil T, King, Ann D, Wang, Ki, Mo, Frankie, Zee, Benny C Y, Chan, K C Allen, Lo, Y M Dennis

“…Purpose The contribution of adjuvant chemotherapy after chemoradiation therapy (CRT) in nasopharyngeal cancer (NPC) remains controversial. Plasma Epstein-Barr…”
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Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients by Kim, Kelly Y., Le, Quynh-Thu, Yom, Sue S., Ng, Raymond H.W., Chan, K.C. Allen, Bratman, Scott V., Welch, John J., Divi, Rao L., Petryshyn, Raymond A., Conley, Barbara A.

“…Epstein-Barr virus (EBV) DNA analysis has been shown to be useful for early detection, prognostication, and monitoring of treatment response of nasopharyngeal…”
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Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non - Small Cell Lung Cancer Patients by YUNG, Tony K. F, CHAN, K. C. Allen, MOK, Tony S. K, TONG, Joanna, TO, Ka-Fai, LO, Y. M. Dennis

“…We aim to develop a digital PCR-based method for the quantitative detection of the two common epidermal growth factor receptor (EGFR) mutations (in-frame…”
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Personalized therapy for hepatocellular carcinoma: Where are we now? by Chan, Stephen L, Wong, Alissa M, Lee, Kirsty, Wong, Nathalie, Chan, Allen K.C

“…Highlights • A number of clinical trials which adopted strategy of ‘All-comer’ accrual failed to identify novel targeted treatment for treatment of…”
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Cell-free DNA in maternal plasma and serum: A comparison of quantity, quality and tissue origin using genomic and epigenomic approaches by Wong, Felix C.K., Sun, Kun, Jiang, Peiyong, Cheng, Yvonne K.Y., Chan, K.C. Allen, Leung, Tak Y., Chiu, Rossa W.K., Lo, Yuk Ming Dennis

“…The objectives of this study were to compare the concentrations, size profiles and major tissue contributors of cell-free DNA (cfDNA) in plasma and in serum…”
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Plasma Epstein-Barr Viral Deoxyribonucleic Acid Quantitation Complements Tumor-Node-Metastasis Staging Prognostication in Nasopharyngeal Carcinoma by Leung, Sing-fai, Zee, Benny, Ma, Brigette B, Hui, Edwin P, Mo, Frankie, Lai, Maria, Chan, K C Allen, Chan, Lisa Y S, Kwan, Wing-hong, Lo, Y M Dennis, Chan, Anthony T C

“…To evaluate the effect of combining circulating Epstein-Barr viral (EBV) DNA load data with TNM staging data in pretherapy prognostication of nasopharyngeal…”
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Systematic evaluation of circulating inflammatory markers for hepatocellular carcinoma by Chan, Stephen L., Chan, Anthony W.H., Chan, Allen K.C., Jian, Peiyong, Mo, Frankie, Chan, Charles M.L., Mok, Kevin, Liu, Calvin, Chong, Charing C.N., Chan, Anthony T.C., Mok, Tony, Yeo, Winnie

“…Backgrounds & Aims A number of circulating inflammatory factors are implicated in the pathogenesis and prognostication of hepatocellular carcinoma (HCC). We…”
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Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients by Lee, Nelson, Allen Chan, K.C., Hui, David S., Ng, Enders K.O., Wu, Alan, Chiu, Rossa W.K., Wong, Vincent W.S., Chan, Paul K.S., Wong, K.T., Wong, Eric, Cockram, C.S., Tam, John S., Sung, Joseph J.Y., Lo, Y.M. Dennis

“…The effect of corticosteroid treatment on the viral load of Severe Acute Respiratory Syndrome (SARS) patients is unknown. To compare the plasma SARS-CoV RNA…”
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Effects of nucleases on cell-free extrachromosomal circular DNA by Sin, Sarah Tk, Deng, Jiaen, Ji, Lu, Yukawa, Masashi, Chan, Rebecca Wy, Volpi, Stefano, Vaglio, Augusto, Fenaroli, Paride, Bocca, Paola, Cheng, Suk Hang, Wong, Danny Kl, Lui, Kathy O, Jiang, Peiyong, Chan, K C Allen, Chiu, Rossa Wk, Lo, Y M Dennis

“…Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear DNA has recently gained increasing research interest, with possible…”
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Pre-examination factors affecting molecular diagnostic test results and interpretation: A case-based approach by Payne, Deborah A., Baluchova, Katarina, Peoc'h, Katell H., van Schaik, Ron H.N., Chan, K.C. Allen, Maekawa, Masato, Mamotte, Cyril, Russomando, Graciela, Rousseau, François, Ahmad-Nejad, Parviz

“…Multiple organizations produce guidance documents that provide opportunities to harmonize quality practices for diagnostic testing. The International…”
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Persistent Aberrations in Circulating DNA Integrity after Radiotherapy Are Associated with Poor Prognosis in Nasopharyngeal Carcinoma Patients by CHAN, K. C. Allen, LEUNG, Sing-Fai, YEUNG, Sze-Wan, CHAN, Anthony T. C, LO, Y. M. Dennis

“…Purpose: Aberrations of circulating nucleic acid integrity have been observed in cancer patients. However, the clinical significance of such changes has not…”
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Quantitative Analysis of the Transrenal Excretion of Circulating EBV DNA in Nasopharyngeal Carcinoma Patients by CHAN, K. C. Allen, LEUNG, Sing F, YEUNG, Sze W, CHAN, Anthony T. C, LO, Y. M. Dennis

“…Purpose: The existence of transrenal clearance of circulating cell-free DNA is controversial. In this study, we used NPC as a model to investigate if…”
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Serologic Antienzyme Rate of Epstein-Barr Virus DNase-Specific Neutralizing Antibody Segregates TNM Classification in Nasopharyngeal Carcinoma by JIE XU, WAN, Xiang-Bo, ZENG, Yi-Xin, LIU, Quentin, HANG, Xue-Fei, CHAN, K. C. Allen, HONG, Ming-Huang, WANG, Li-Hui, LONG, Zi-Jie, QING LIU, MIN YAN, LO, Y. M. Dennis

“…We investigate the value of pretreatment serologic antienzyme rate (AER) of Epstein-Barr virus (EBV) DNase-specific neutralizing antibody complementing TNM…”
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Correlations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma by Li, Leung, Chan, Stephen L, Mo, Frankie, Hui, Edwin P, Koh, Jane, Chan, Allen K C, Tang, Nelson L S, Lee, Kit F, Lai, Paul B S, Yu, Simon C H, Yeo, Winnie

“…Health-related quality of life (HRQoL) is a significant prognostic factor for overall survival in hepatocellular carcinoma (HCC) patients, and this is…”
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Circulating EBV DNA as a tumor marker for nasopharyngeal carcinoma by Allen Chan, K.C, Dennis Lo, Y.M

“…The demonstration of Epstein–Barr virus (EBV) DNA in the plasma/serum of patients suffering from nasopharyngeal carcinoma (NPC) has provided us with a new tool…”
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Plasma Epstein-Barr virus DNA as a biomarker for nasopharyngeal carcinoma by Chan, K C Allen

“…Nasopharyngeal carcinoma （NPC） is common in southern China and Southeast Asia. Epstein-Barr virus （EBV） infection is an important etiology for NPC, and EBV…”
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Reduced Plasma RNA Integrity in Nasopharyngeal Carcinoma Patients by WONG, Blenda C. K, CHAN, K. C. Allen, CHAN, Anthony T. C, LEUNG, Sing-Fai, CHAN, Lisa Y. S, CHOW, Katherine C. K, LO, Y. M. Dennis

“…Purpose: Recent research has shown the feasibility of detecting cell-free RNA markers in human subjects. As elevated RNase activity has previously been…”
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